Hey all, I'm back on the board after 7 years. Found out last Friday that I have mets to the liver. I'm wondering this time around what can be done differently in treatment in hopes for a better outcome. Original dx is DCIS, <2cm, ER/PR+, lumpectomy, 4 rounds of AC, radiation, tamoxifen, zoladex injections to suppress ovaries.
I'm disappointed that not much seems to have changed in standard protocol, surgery, chemo, radiation, hormonal treament. I'm searching for new ideas and developments in molecular pathways, biomarkers, more targeted therapies, etc. My questions pertain to a couple of areas:
1. Has anyone had tumor tissue from surgery sent off for targeted chemo or other treatment testing? If yes, what tests were performed (i.e. chemo, biological, etc.)? What has been your progress?
2. If you have or had mets, what different treatment options were explored or used other than chemo or hormonal treatments?
Thanks to everyone in advance for your answers and support.
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Gitane Joined: Feb 2008 Posts: 829 |
Oct 30, 2009 12:38 am
Gitane wrote:
I do not have mets. However, I want to share with you that chemosensitivity testing was done on my tumor to see which chemos would or would not work. I felt it was a very useful thing to do. My testing was done by Rational Therapeutics. A tumor sample must be sent to them directly after surgical removal. Rational Therapeutics, 750 East 29th Street , Long Beach, CA (1 562 989-6455), www.rationaltherapeutics.com Dx 8/18/05, Pleomorphic ILC, multifocal, multicentric, G2, 1/9 nodes positive, OncotypeDX 23, ER+ PR- Her2-
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KattyC Joined: Oct 2009 Posts: 13 |
Oct 30, 2009 09:06 am, edited Oct 30, 2009 03:49 PM
by KattyC
KattyC wrote:
Thanks Gitane, I knew there was something like this out there, just didn't know the company that provides the testing. Have you also heard of any other testing for molecular pathways/biomarkers from a biological or hormonal treatment perspective vs. a chemo perspective? Also if I might ask, how did your Onc. monitor your progress with your chemo treatment selection? I hear there is a 'CTC' simple blood test that measures the number of cancer cells ciculating in a given sample. This can be performed at the Onc.'s office during scheduled visits. Does anyone have any experience with this or any other non-traditional methods (i.e. not the usual scans, mammo, chest x-rays, etc.) . Thanks again, I meet with the surgeon this morning to discuss recommendation for resection in about an hour. I'll post with any new information I gain from the meeting. Diagnosis: 10/23/2009, 1cm, Stage IV, ER+/PR+ |
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Gitane Joined: Feb 2008 Posts: 829 |
Nov 1, 2009 05:20 pm, edited Nov 1, 2009 05:24 PM
by Gitane
Gitane wrote:
I don't know of any other special biomarkers or tests. Sorry. I wish I could help more. Was the surgeon helpful? My oncologist did pre/post treatment MRIs to monitor the tumor shrinkage. Since I had neoadjuvant chemo, he did the chemosensitivity testing on tumor taken from the post treatment mastectomy to see if my tumor would respond to any more treatment. It still was responding to AC, so I got 2 more rounds of that. He's doing 15-3 tumor markers to follow me now. Dx 8/18/05, Pleomorphic ILC, multifocal, multicentric, G2, 1/9 nodes positive, OncotypeDX 23, ER+ PR- Her2-
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