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Topic: Possible to be grade 1 and triple neg?

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Joined: Jul 2008
Posts: 115
  • Posted on: Aug 24, 2008 07:00 am
Lynette wrote:

I haven't had my hormone status results yet but I was wondering whether grade 1 IDC can be triple neg?


Dx 7/30/2008, IDC, 1cm, Grade 1, 1/2 nodes
Posts 1 - 10 (10 total)
galnok
Joined: Dec 2006
Posts: 401
Aug 24, 2008 12:55 pm, edited Aug 24, 2008 12:57 PM by galnok galnok wrote:
This Post was deleted by galnok.
AnnNYC
Joined: Aug 2007
Posts: 2132
Aug 24, 2008 01:14 pm AnnNYC wrote:

Lynette, I had to look for an answer to this.  My initial thought was that this was a very good question, and theoretically it's possible, but perhaps unlikely.


I found a report of a study of 145 triple-negative breast cancers at NYU Cancer Institute: 11 were Grade 1, 23 were Grade 2, and 111 were Grade 3.

Here's a link: http://www.sciencedaily.com/releases/2008/04/080411150927.htm


Dx 3/9/2007, IDC, <1cm, Stage I, Grade 2, 0/5 nodes, ER+/PR+, HER2-
AnnNYC
Joined: Aug 2007
Posts: 2132
Aug 24, 2008 01:19 pm, edited Aug 24, 2008 01:21 PM by AnnNYC AnnNYC wrote:

But Lynette, one thing to remember is that only 15% of breast cancers are triple negative. So, if only 7.5% of triple negative cancers are grade 1 (according to the NYU study), then I think there's probably only about a 1% chance that your grade 1 IDC will come back as triple negative.


Dx 3/9/2007, IDC, <1cm, Stage I, Grade 2, 0/5 nodes, ER+/PR+, HER2-
Shirlann
Joined: Feb 2002
Posts: 6756
Aug 24, 2008 07:11 pm Shirlann wrote:

I was grade one, Triple Negative, but it was stage 4.  (most of the trinegs are stage 4) Tiny cancer, but a triple neg.  I am fine almost 10 years later.  But we will see.

Gentle hugs, Shirlann 
chumfry
Rochester, MN
Joined: Sep 2005
Posts: 520
Aug 25, 2008 12:01 pm chumfry wrote:

Shirlann, you were Stage IV?? Isn't that mets?

I was under the impression that most triple-negs were Grade 3 because they tend to grow so fast.

--CindyMN
arby
Joined: Nov 2007
Posts: 38
Aug 28, 2008 08:35 pm arby wrote:

I was trip-neg and stage 1  supposedly DCIS but they found invasive component the size of a pea when the lumpectomy was done.  I did 35 RAD treatments, that's all.
smithlme
East Bay, CA
Joined: Dec 2007
Posts: 509
Aug 28, 2008 08:44 pm smithlme wrote:

I was a stage 2 grade 3 triple negative the first time around. Fast growing and aggressive but not a stage 4...

Linda

Dx 3/31/08, DCIS, ER+/PR- BRCA2+ "In the book of life, the answers aren't in the back." Charlie Brown
Dx 3/28/2007, IDC, 2cm, Stage II, Grade 3, 0/9 nodes, ER-/PR-, HER2-
Malady
Joined: Sep 2007
Posts: 19
Aug 29, 2008 04:56 pm, edited Aug 29, 2008 04:58 PM by Malady Malady wrote:

I was Stage 1, Grade 1 and  triple negative.   I choose not to do chemo even though my Oncologist (who I did not like)  recommended that I have it


Dx 9/11/2007, IDC, 1cm, Stage I, Grade 1, 0/2 nodes, ER-/PR-, HER2-
bar62
New York, NY
Joined: Aug 2008
Posts: 92
Aug 31, 2008 10:44 am bar62 wrote:

I am triple negative grade 3. My Oncologist plugged me into her computer and told me that  my recurrence chances were high>40% without Chemo. She scared me silly so I will have chemo and rad because I had a Lumpectomy.


Dx 6/6/2008, IDC, 3cm, Stage IIa, Grade 3, 0/19 nodes, ER-/PR-, HER2-
Summer
Joined: Jun 2008
Posts: 1103
Sep 1, 2008 02:18 am Summer wrote:

Grade 3 Stage 1, chemo + radiation treatment 7 years ago.  Apparently the majority of these tumors are grade 3.  Research suggests that triple negative breast cancer responds well to chemotherapy, greatly reducing the risk of a recurrence.

Summer
Dx 10/12/2001, IDC, 1cm, Stage I, Grade 3, 0/8 nodes, ER-/PR-, HER2-

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