Topic: Zometa Clinical Trial

Hi Lesleyann, 

I  seriously considered the Zometa trial after two med onco's recommended it to me.  Recent trials have shown it to help prevent recurrence and strenghthen bones.  My insurance approved me for off-label use twice a year, as per the Austrian trial, so I went with that, and my onco seemed  very pleased with that option too. 

There is a rare but very nasty side effect to the Zometa: osteonecrosis of the jaw.  I believe it is less prevalent if you get the oral form of the drug, but you should verify that.  If you do opt for the trial, be sure to visit your dentist beforehand and have any major work done if you can.

I have included some links to previous and ongoing discussions about the bisphosphonate trial and Zometa that have lots of info and links to studies. Can't seem to hyperlink on this site!

http://community.breastcancer.org/forum/67/topic/724607?page=7#idx_196

http://community.breastcancer.org/forum/6/topic/729712?page=7#idx_206

http://community.breastcancer.org/forum/78/topic/740234?page=1#idx_9

I think this trial is  very exciting.  My onco and others at his hospital believe Zometa and/or bisphosphonates will be standard of care in the future if results of current studies continue to be positive for helping prevent recurrence.

Best of luck!