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Dec 4, 2012 08:31AM cp418 wrote:
Metformin May Improve Survival Rate Of Patients With Ovarian Cancer.
CBS News (12/4) reports on a study published online in the journal Cancer finding that metformin, "a common diabetes medication...may be used in the prevention or treatment of ovarian cancer." Explaining the study, "Dr. Elizabeth Poynor, a gynecologist and cancer specialist" appeared on "CBS This Morning." She said that while the study found "that women who had ovarian cancer who took Metformin for diabetes actually had a 20 percent better survival rate from the disease than women who did not take Metformin," yet "it's not yet known why this is the case." Poynor pointed out that a number of studies have looked "at Metformin with different cancers, such as prostate cancer, pancreas cancer, colon and breast cancer. It may have widespread implications to many different types of malignancies."
HealthDay (12/4, Marcus) explains that metformin "is derived from French lilacs. It's typically prescribed to lower blood sugar levels in people with type 2 diabetes but has shown promise as a potential anticancer agent in recent prostate, colon, pancreas, brain and breast cancer studies, as well as in lab experiments with ovarian cancer cells." The study in question "evaluated the medical records of ovarian cancer patients who had received their cancer diagnosis between 1995 and 2010. Sixty-one patients were taking metformin at the time of their cancer diagnosis while 178 patients -- the control group -- weren't on the medication." It found that "67 percent of the women using metformin had not died within five years of their diagnosis, while only 47 percent of the control group had survived that long."
MedPage Today (12/4, Fiore) reports that the study's authors concluded, "Metformin is worthy of clinical trials in ovarian cancer."
WebMD (11/30, Boyles) reports, "The study is just one of dozens under way worldwide examining the drug -- which costs just pennies a pill -- as a treatment for breast, colon, prostate, pancreatic, and ovarian cancers."
Fox News (12/3, Grush) reports on its website, "As for why the diabetes drug is so protective against cancer, the researchers cannot say for sure – but there are a few theories." One is that it "seems to inhibit the energy supply to the cell," and "may be acting on the cancer stem cells."