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Topic: Sleep Apnea Tied to Increased Cancer Risk

Forum: Clinical Trials, Research, News, and Study Results — Share your research articles, interpretations and experiences here. Let us know how these studies affect you and your decisions.

Posted on: Jun 29, 2012 08:46 AM

Ruby- wrote:

I'm currently being treated for sleep apnea diagnosed 6 months ago and trying to get used to the different masks that come with the CPAP machine.  When finally dx, I had the gut feeling that maybe, just maybe, correcting the apnea would go a very long way in preventing recurrence. Crossing fingers

"Two new studies have found that people with sleep apnea, a common disorder that causes snoring, fatigue and dangerous pauses in breathing at night, have a higher risk of cancer. The new research marks the first time that sleep apnea has been linked to cancer in humans. 

In one of the new studies, researchers in Spain followed thousands of patients at sleep clinics and found that those with the most severe forms of sleep apnea had a 65 percent greater risk of developing cancer of any kind.

The second study, of about 1,500 government workers in Wisconsin, showed that those with the most breathing abnormalities at night had five times the rate of dying from cancer as people without the sleep disorder. Both research teams only looked at cancer diagnoses and outcomes in general, without focusing on any specific type of cancer.

The researchers found that the more severe a person's breathing problems at night, the greater the likelihood of dying from cancer. People with moderate apnea were found to die of cancer at a rate double that of people without disordered breathing at night, while those in the severe category died at a rate 4.8 times that of those without the sleep disorder'"

well.blogs.nytimes.com/2012/05...

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 29, 2012 01:01 PM jenrio wrote:

Interesting study.  

Sleep apnea is correlated with obesity and melatonin, which in turn is correlated with diabetes and breast cancer.   It's hard to tease out which is cause which is effect.

more details in my blog killerboob.blogspot.com
Dx 8/29/2011, IDC, 2cm, Grade 3, 1/1 nodes, ER+/PR+, HER2-
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Jun 29, 2012 01:30 PM, edited Jun 29, 2012 01:33 PM by Ruby-

Hi Jen, it's the lack of oxygen (hypoxemia or oxygen depletion) in sleep apnea that appears to be the culprit. My sleep study concluded that I stop breathing 70 times per hour....

"Scientist speculate that depriving mice of oxygen may cause their bodies to develop more blood vessels to compensate, an effect that could act as a kind of fertilizer for cancer tissue and cause tumors to grow and spread more quickly"

Of course, no sleep = a lot of health problems and I'm sure melatonin plays a role in all of it. That's why I've started taking it before bed (when I think about it...often times forget, but religiously take my cal/mag/K2. Magnesium is a miracle worker as far as I can tell)

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 29, 2012 01:37 PM jenrio wrote:

I c.  interesting.   what is K2?

more details in my blog killerboob.blogspot.com
Dx 8/29/2011, IDC, 2cm, Grade 3, 1/1 nodes, ER+/PR+, HER2-
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Jun 29, 2012 06:11 PM, edited Jun 29, 2012 06:13 PM by Ruby-

K2 = menaquinone7, mine is extracted from natto bean. Vit K also fills the needs for coagulation, can be found in cheese, veges which I neglect as I'm a fruit person....  I learned on these boards that I had been taking calcium for years and years but barely absorbing it although I never never take it without magnesium (calcium also needs magnesium for absorption) and had a superb bone density scan.

"Dietary Intake of Menaquinone Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study"

jn.nutrition.org/content/134/1...

In clinical trial for bone loss and arteriosclerosis (huge family history)

clinicaltrials.gov/ct2/show/NC...

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 29, 2012 06:25 PM Ginger48 wrote:

Very interesting. I recently had a sleep study and was diagnosed with severe obstructive sleep apnea due to stopping breathing 45 times per hour. The mask is definitely taking some getting used to. I have no idea what came first...the apnea or the cancer. My snoring definitely increased after BMX and weight gain.

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jun 29, 2012 06:44 PM Ruby- wrote:

Hi Ginger ! glad to find a sister to commiserate with ! No kidding about the mask...hate to say it but when I went for my sleep study, the image of Hannibal Lekter came to mind, I became claustrophobic and had the worse nightmare Frown  Because I have very dry eyes, all the stupid masks I tried have made it worse.  So, finally today, I went to another lab with better techs and came away with the nasal pillow system.  I now know I can adjust humidity, will be using a nose spray before retiring and hopefully will be having sweet dreams tonight !  Hope you are doing better than I am....
“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 29, 2012 06:47 PM Ginger48 wrote:

I have dry eye syndrome too and it feels like it is getting worse. What is the nasal pillow system? I am currently wearing a mask that covers nose and mouth but I am noticing some air seeping out from the mouth area when I change head positions.

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jun 29, 2012 06:57 PM, edited Jun 29, 2012 06:59 PM by Ruby-

Ginger, we must be twins  Lol

brrrrr that mask that covers nose and mouth... I know, very rigid, not flexible at all, the leaks kept waking me up Frown

Did you buy the machine ?  If so, you should be able to exchange masks no problem until you find one that fits you perfectly. The 'nasal' mask I got is this one:

www.cpapmachinescanada.com/cpa...

I really hope this works, as it's my last resort !  It should fit much better cause it's made for us women  Innocent

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 29, 2012 07:02 PM Ginger48 wrote:

Maud- CPAP twins, ha! I could not get that link to open. My insurance covered the machine so I am the proud owner. I also have a nasal mask but have not used it as I tend to be a mouth breather sometimes. But maybe I will try it. I get about 3 or 4 hours of ok sleep but after that I just want to rip that mask off my face. The nights seem soooo long!

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jun 29, 2012 07:07 PM camillegal wrote:

Wow how interesting.  I always thought that happened to more men than women--but what do I know---I'm sorry u have another problem to deal with.

Dx 2007, Stage IV, HER2+
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Jun 29, 2012 07:11 PM, edited Jun 29, 2012 07:11 PM by Ruby-

Hello CPAP twin, lol ! shucks about the link, maybe try it again, I edited my post and fixed it.  You know... I had the same darn problem, I'm a mouth breather too ! First ever mask was a nasal one and I was waking up gaging and choquing, I swear.  That's why they tried all those other masks, but a real smart tech told me about the chin restraints, have you heard about that one ? really sexy stuff if I may say so myself....Kiss

www.cpapmachinescanada.com/cpa...

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 29, 2012 07:19 PM Ginger48 wrote:

Haha! I got one of the chin straps with the nasal mask at my sleep study. It looks ridiculous but I may give it a try tonight. I will try the link again.

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jun 29, 2012 08:05 PM Ruby- wrote:

Re wanting to rip off your mask, I'm so good at it that I do it without waking up Lol

The bright tech today adjusted something to do about expiration (breathing out) rate....? sorry, can't remember the medical term.  Tell your tech about it, I felt the same, like I just could not breathe, was suffocating and they adjusted this setting on my chip.  Have you raised your humidity setting, mine is up to 4.5 goes to 6 and you can adjust that yourself with the button on the machine.  It has helped somewhat

Let me know how your set up worked, see you in the mornin' CPAP twin Wink

Camillegal, I know, I told them I did not fit the profile ! 

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 29, 2012 09:26 PM Ginger48 wrote:

I will check out my levels tonight. I think it is at 8 but I have a button that starts it out more slowly and works up to full pressure.

Nighty-night!

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jun 30, 2012 11:39 AM Ginger48 wrote:

Maud- my level is 8 but starts out at 4. I did pretty well with nasal mask and chin strap last night so I will try it again tonight. Hope you slept well!

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jun 30, 2012 01:10 PM Ruby- wrote:

Hey Ginger, glad you did well !! no small feat little twin sister ;)  I took a break last night Embarassed gotta clean out the tube and water reservoir, all fresh to go with the same gear as you, hoping to do as well as you did !  Am seeing the respirologist next week with my last print out, a real embarrassment, I barely kept the mask on for an hour a night....he scheduled me for another sleep study in December, reallllly looking forward to that Cry
“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 30, 2012 02:00 PM Ginger48 wrote:

Hmmm...no one has mentioned a follow up appt or checking the data on my machine. May have to ask if they plan to do that. Definitely not looking forward to a sleep study with all those wires

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jun 30, 2012 09:37 PM Ruby- wrote:

Hi Ginger, getting ready for the gear soon Frown yes, you should enquire about follow-up, you mean nobody is reading your chip ?  I have to tell them to spare me...they want to follow up on a monthly basis, sometimes I have to go back within two weeks, takes a lot of tweaking before we can be made comfortable, you know...

Sweet dreams ;) 

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jun 30, 2012 09:44 PM Ginger48 wrote:

No one has even mentioned reading my chip. Sweet dreams!

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jul 1, 2012 07:33 AM Ruby- wrote:

Hi Ginger, did not do so well last night, I vaguely remember tearing the mask off - don't know how long I was able to tolerate it.  Looks like I've fallen into a pattern Frown  Hopefully, the respirologist will have some idea on how to tweak the machine so that I can do this....will keep trying.....  One tech told me that I had central apnea and because of this, it would take as long as 6 months to get used to the whole thing - it's been over 6 months now Cry  I so want this to work because I firmly believe that it will help us somehow in preventing a recurrence

Have a beautiful day ! 

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jul 1, 2012 07:52 AM Ginger48 wrote:

Sorry to hear that. I packed up my machine and lugged it to stay at my mom's ladt night. I did ok with nasal mask and chin strap but it leaves big grooves in my face when I wake up. Not sure if that is typical or I am wearing it too tight. I never take the mask off before 5 am. I just have disturbed sleep at this point but do not wake up feeling like I waged a war. Hope you get it figured out.

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jul 1, 2012 08:24 AM, edited Jul 1, 2012 08:26 AM by Ruby-

Really glad to hear you're doing well Ginger !  I'm being encouraged to persist and told that this could be life changing Tongue out

I had leaking so maybe mine is not tight enough, no grooves showing Lol  

Keep me posted on your follow-ups and readings Wink  

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jul 1, 2012 06:24 PM jenrio wrote:

I have had lots of sleep issues too.   Thanks Maud for sharing.   I'll try to fix the melatonin by less lighting at night and eating more cherries Laughing
more details in my blog killerboob.blogspot.com
Dx 8/29/2011, IDC, 2cm, Grade 3, 1/1 nodes, ER+/PR+, HER2-
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Jul 1, 2012 08:18 PM Ruby- wrote:

cherries, yummie, they're good for pain too.  Insomnia is HORRIBLE ! the doc told me my insomnia found in a sleep study 20 + years ago is a separate problem, WTH ???

Have you had a sleep study done Jen ?  Sleep issues need to be resolved especially with our BC 

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jul 1, 2012 08:20 PM Ruby- wrote:

Knock knock Ginger, I meant to ask you, what's your pressure at ?  Mine is set at 11 but the doc wants me at 15 Frown
“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jul 1, 2012 09:50 PM jenrio wrote:

I did the sleep study.   I think they didn't find anything.   But I do have bad sleep habit of getting up mid night to go online, etc...  probably messed up my melatonin.

Ambien works for me too.   But cherries are better. 

more details in my blog killerboob.blogspot.com
Dx 8/29/2011, IDC, 2cm, Grade 3, 1/1 nodes, ER+/PR+, HER2-
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Jul 1, 2012 10:22 PM Ginger48 wrote:

Hi maud, my pressure is at 8 but I push a button and it starts out at 4 and builds up gradually. I am getting ready for night 3 with nasal mask and chin strap.

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jul 2, 2012 07:29 AM Ruby- wrote:

Thanks Ginger, hope you had a restful sleep, ahhhhhh, that will be the day for me !!!

Wonder if my pressure is too high....again took the mask off last night.....hope the doc knows what he's doing Yell seeing him on Thursday - because right now, this whole thing is defeating the purpose....I usually pass out in a minute when I go to bed, now with the mask on, it takes me aaaaages to fall asleep

Jen, getting up in middle of the night to surf....now, that's a bad habit, maybe double up on the cherries,  Lol 

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-
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Jul 2, 2012 07:36 AM Ginger48 wrote:

Sorry you are not getting more relief. I won't let myself take the mask off till the sun is coming up. Just force myself to reposition and go back to sleep.

BRCA2+ Knowledge is power! lumpectomy 4/12/11, NSBMX 6/22/11, exchange to implants 10/27/11, ooph 12/7/11
Dx 4/5/2011, IDC, <1cm, Stage I, 0/1 nodes, ER+/PR+, HER2-
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Jul 2, 2012 07:57 AM Ruby- wrote:

Ginger, I need to force myself - the things is, I barely realize I'm taking it off.  It's become a bad habit like Jen here with surfing Tongue out

Will see how it goes tonight.  The new nasal mask is a real cadillac, Lol  At last, no problem there, it must be the pressure or something else....

“God will not look you over for medals, degrees or diplomas but for scars.” ― Elbert Hubbard -- How somebody treats me is their Karma, how I react is my Karma
Dx 2010, IDC, 2cm, Stage IIb, Grade 1, 3/5 nodes, ER+/PR+, HER2-

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