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Topic: Who watched Stand Up to Cancer?....

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Joined: Jun 2007
Posts: 130
  • Posted on: Sep 5, 2008 09:22 pm, edited Sep 5, 2008 09:23 PM by Carolina59
Carolina59 wrote:

I was putting my daughter to bed and missed this, but my dh said there was a Her2+, Stage IV bc survivor who was treated only with Herceptin? Tykerb?--he doesn't remember what it was. Did anyone see this? I want to know more.  

Dx 5/31/07: left, DCIS; right, DCIS (10cm) & IDC (multifocal >2cm); Stage I, grade 3, 0/12 nodes, ER+/PR+/HER2+; bilateral mast. 6/26/07; chemo, no rads; ooph 2/29/08

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TammyLou
Joined: Dec 2006
Posts: 392
Sep 5, 2008 09:37 pm TammyLou wrote:

I think they said she had a cancer in her breast that was so big that it was busting through the skin AND lung mets.

2.5 years NED.

I think that she currently takes Herceptin only.  I can't imagine that sort of response to Herceptin only AND protocol indicates chemotherapy for visceral (lung) mets.

Tammy Lou

TammyLou
Joined: Dec 2006
Posts: 392
Sep 5, 2008 09:39 pm TammyLou wrote:

P.S.  One of the young survivors (www.youngsurvival.org)

Marin514 cleaned up her liver with taxotere and herceptin.  (NED)

6-8 months later she popped a coupla' hot lymph nodes...but her liver is clean as a whistle.

(No kidding!)

Tammy Lou

Dejaboo
Joined: Mar 2008
Posts: 1136
Sep 5, 2008 09:41 pm Dejaboo wrote:

I saw that to & thought - what is this?  They said she never had Chemo.

I forget exactly how they worded her treatment....I dont think they said she was taking herceptin...I thought they worded it different...I cant remember Foot in mouth

Pam

Dx 3/7/2008,DCIS, IDC-1.2mm, Stage I, Grade 1, 0/1 nodes, ER+/PR-, HER2+, Lump/SNB-4/1/08, Bilat 5/22/08
wishiwere
MI
Joined: Dec 2007
Posts: 3066
Sep 5, 2008 09:42 pm wishiwere wrote:

It's supposed to be rerun on sunday morning at 11:00 am, I believe they said.  You can go to wzzm13.com to get some info from it. 

wishiwere
Dx 9/21/2007, ILC, 1cm, Stage Ib, Grade 2, 0/4 nodes, ER+/PR+, HER2-
suemed8749
Phoenix, AZ
Joined: Jan 2008
Posts: 498
Sep 5, 2008 11:24 pm suemed8749 wrote:

I was surprised too when they said she never had chemo. I know she was treated with Herceptin - Am I right in thinking she was in a clinical trial? She was answering phones on the stage and looked gorgeous.


Dx 1/15/2008, IDC, 2cm, Stage IIa, Grade 3, 0/3 nodes, ER-/PR-, HER2+
lexi4
Joined: Nov 2005
Posts: 2051
Sep 6, 2008 12:48 am, edited Sep 6, 2008 12:49 AM by lexi4 lexi4 wrote:

Yes,I think they said that she has weekly herceptin txs. She looked great! ANd healthy!


Dx 8/22/2005, IBC, 3cm, Stage IIIb, Grade 3, 5/6 nodes, ER-/PR-, HER2+
rohmdesign
Joined: Sep 2008
Posts: 1
Sep 6, 2008 02:47 am rohmdesign wrote:

She was treated at a medical facility in CA. They did not mention herceptin, only that she did not have chemo, but was treated with a medication that is developed in the lab and only distroyed the cancer cells while her healthy cells were not harmed. Sounds like herceptin to me, but they did not say that is what is was. Let me know if anyone finds out her name and any other details!

Daffodil
Joined: Apr 2008
Posts: 486
Sep 6, 2008 03:23 am, edited Oct 13, 2008 07:04 AM by Daffodil Daffodil wrote:
This Post was deleted by Daffodil.
Joni0702
Joined: Nov 2007
Posts: 128
Sep 6, 2008 09:06 am Joni0702 wrote:

She definitely did not have chemo.  They did not say she had Herceptin - I think they may have said gene therapy that attacked only the cancer cells.  She was definitely HER2+.  My immedicate response was "wow, Herceptin without chemo - why wouldn't they give that to me?".  However, they did not say Herceptin.  I would love to know as well. 

Carolina59
Joined: Jun 2007
Posts: 130
Sep 6, 2008 10:00 am Carolina59 wrote: Thanks, everyone. Yes, my dh said they definitely did NOT mention Herceptin--he would've remembered it since I was on it for one year. I guess I'm glad I got the chemo, too, (TCH) so I feel I've attacked the cancer with everything possible. But I'm very interested in the new txs that target the Her2+. 

Thanks for the info that they are going to rebroadcast. I'll try to watch it. 
Dx 5/31/07: left, DCIS; right, DCIS (10cm) & IDC (multifocal >2cm); Stage I, grade 3, 0/12 nodes, ER+/PR+/HER2+; bilateral mast. 6/26/07; chemo, herceptin, no rads; ooph 2/29/08
EGAL
RI
Joined: Apr 2007
Posts: 123
Sep 6, 2008 12:49 pm EGAL wrote:

I saw that also and thought "I'm Stage 3 and I had 8 rounds of chemo, bilateral masectomy, radiation and Herceptin.  They did not mention the word Herceptin but that is what it must have been.  I told my DH I as going to ask my Ocon in two weeks when I have an appt. if that is really possible.  I would like to have been "cured" without the treatments that I had to endure.

EGAL
Dx 10/19/2006, IDC, 6cm+, Stage IIIc, Grade 3, 15/17 nodes, ER-/PR-, HER2+
kimbly
MI
Joined: Feb 2008
Posts: 255
Sep 6, 2008 12:52 pm kimbly wrote:

I could have sworn they did mention Herceptin but perhaps with them talking about her being her2+ I just assumed.  Sure sounds like it to me.  I also was amazed that she had no chemo with a tumor that large.  I have chemo and herceptin (currently still on herceptin every 3wks) and it is so wonderful to hear a story like that. 


Dx 11/21/2007, IDC, 1cm, Stage I, 0/3 nodes, ER+/PR+, HER2+
Brenda_R
IL
Joined: Dec 2006
Posts: 295
Sep 6, 2008 01:55 pm Brenda_R wrote:

It looks like you can watch it on the web here-

http://www.nbc.com/Movies_Specials_More/Stand_Up_To_Cancer/video/episodes/ 

Positive Internal mammary node, 3.7cm bi-lobed tumor
Dx 12/12/2006, IDC, 3cm, Stage IIIa, Grade 3, 1/17 nodes, ER-/PR-, HER2+
tomatojuice…
New york
Joined: Mar 2008
Posts: 255
Sep 6, 2008 02:29 pm tomatojuice wrote:

I saw it too. Did not hear them mention herceptin, only something about being treated with some kind of antibodies?THey said her tumor was so large, it burst right out of the breast tissue. She looked great, healthy, beautiful and strong.And she was NED.She didn't have chemo or rads.


Dx 2/26/2008, IDC, 2cm, Stage IIb, Grade 3, 3/18 nodes, ER-/PR-, HER2+
Maryiz
Joined: Dec 2007
Posts: 484
Sep 6, 2008 02:42 pm Maryiz wrote:

Carolina 59, Just to let you know, they are doing vaccine trials that target HER2 and say they are very promising.  Johns Hopkins is one place that is doing this trial.  Lets hope it can stop it in its tracks. Maryiz

Joni0702
Joined: Nov 2007
Posts: 128
Sep 6, 2008 05:53 pm, edited Sep 6, 2008 06:06 PM by Joni0702 Joni0702 wrote:

I am not aware that they are doing the HER2 vaccine trial at Hopkins.  On the east coast, I thought it was only Wake Forest in NC - except for Walter Reed in MD - but you have to be in the arm services.  I just checked their website and they are testing a general breast cancer vaccine.  Please let me know if they are indeed doing the HER2 vaccine clinical trial.  

Joan

Mary-Lou
Virginia Tech Country, Va
Joined: Nov 2005
Posts: 2059
Sep 6, 2008 06:12 pm Mary-Lou wrote: I just watched it, I had to tape it cause I was out of town. . The Her2 gal did have Herceptin but no chemo.. That was what popped out to me and I said something to my husband at the very moment it was mentioned.
I'm 52 , and a Gram of 3 :)
Dx 9/20/2005, IDC, 6cm+, Stage IIIb, Grade 3, 4/4 nodes, ER+/PR+, HER2-
chemosabi
Joined: Jul 2005
Posts: 7780
Sep 6, 2008 06:28 pm, edited Sep 6, 2008 06:29 PM by chemosabi chemosabi wrote: I thought it odd also, that her only treatment was Herceptin without chemo.   
Fear grows in darkness, if you think theres a bogeyman around - turn on the light
Carolina59
Joined: Jun 2007
Posts: 130
Sep 6, 2008 06:40 pm Carolina59 wrote: Does this mean I could've saved my breasts? No bilateral mastectomy, no chemo. I'm amazed. Does anyone know where she was treated?

Thanks for the link, by the way, I will watch it later tonight I hope.
Dx 5/31/07: left, DCIS; right, DCIS (10cm) & IDC (multifocal >2cm); Stage I, grade 3, 0/12 nodes, ER+/PR+/HER2+; bilateral mast. 6/26/07; chemo, herceptin, no rads; ooph 2/29/08
Mary-Lou
Virginia Tech Country, Va
Joined: Nov 2005
Posts: 2059
Sep 6, 2008 06:41 pm Mary-Lou wrote:

Update: I know when I watched it it had the word Herceptin on the screen.

But I just went back and listened to the report and it didn't say she had Herceptin. She was treated with a Lab Created Antibody at UCLA's  Johnson Comprehensive center through a trial study.

She was 1 of 2 of the worst  cases ever seen and had been given 2 months to live, that was two years ago.

Her name was Stephanie Grimes.

I'm 52 , and a Gram of 3 :)
Dx 9/20/2005, IDC, 6cm+, Stage IIIb, Grade 3, 4/4 nodes, ER+/PR+, HER2-
HensonChi
Joined: May 2008
Posts: 170
Sep 6, 2008 07:23 pm HensonChi wrote:

A news report about her that says she did use herceptin.

Unique cancer treatment saves woman

Friday, May 09, 2008   By Denise Dador

LOS ANGELES (KABC) -- A local woman had a breast cancer so aggressive, she could see it on her skin. She didn't have much hope until doctors offered her a unique treatment.

Fitness instructor Stephanie Grimes is the picture of strength and balance.

Click in the Eyewitness News Story Window above to watch the accompanying video.

She rarely gets sick, but in 2006 something she thought was an unusual mosquito bite on her chest ended up being an extremely aggressive form of breast cancer. Doctors told her that it was a severe case.

Story continues below Advertisement

"They told me that it was one of the most severe cases of breast cancer that they had seen," explains Grimes.

The cancer had literally eaten through her chest wall and eventually caused a large open wound.

"At that point I had been given about two months to live," said Grimes.

The disease had spread to her lymph nodes. At this point, standard treatment wouldn't help.

"Chemotherapy for metastatic breast cancer is not curative," said Oncologist John Glaspy, MD.

Dr. Glaspy at UCLA's Jonsson Comprehensive Cancer Center suggested the an experimental drug therapy combination of Herceptin and Avastin.

"The thing that made her cancer really aggressive also gave us a target," explains Dr. Glaspy.

The drugs target proteins that feed the cancer. Within the first few weeks, Stephanie saw her lumps start to disappear.

"They had shrunk tremendously. Externally I could see changes occurring right away," said Grimes.

And except for a little fatigue, she hardly felt any side effects. Two years after she was told she had two months to live, Stephanie's prognosis is very hopeful.

Stephanie's tumor before herceptin and avastin was a substantial size, but after her treatment it shrunk significantly.

"Things are going very well and they may go well indefinitely," said Dr. Glaspy.

"I am truly blessed with the outcome of the treatment that I am on," said Grimes.

The clinical trial is one of many happening at UCLA's Jonsson Comprehensive Cancer Center. And some of the proceeds from the Revlon Run Walk funds their research.


Dx 2/22/2008, ILC, 1cm, Stage IIa, Grade 2, 1/14 nodes, ER+/PR-, HER2+
Little-G
OR
Joined: Oct 2007
Posts: 500
Sep 6, 2008 10:16 pm Little-G wrote:

Right on for posting the link to watch it!!  Thanks for that!

g


Dx 2005, ILC, 1cm, Stage Ib, Grade 3, 0/3 nodes, ER+/PR+, HER2-
Mary-Lou
Virginia Tech Country, Va
Joined: Nov 2005
Posts: 2059
Sep 7, 2008 02:33 pm Mary-Lou wrote:

Thanks for that post, I thought I saw that.

I'm 52 , and a Gram of 3 :)
Dx 9/20/2005, IDC, 6cm+, Stage IIIb, Grade 3, 4/4 nodes, ER+/PR+, HER2-
jan125
Joined: Aug 2006
Posts: 275
Sep 7, 2008 07:26 pm jan125 wrote:

Wow!!!!!!!!!!!!!

I usually post on the mets board, but I am her2+ with mets to bone and liver. NED at present (almost 2 years now!)

I am on herceptin one time every 3 weeks. They can give a shorter infusion 1 time every week, but I like the convience of every 3.

According to my onc. there is a good possibility that herecptin only will become the new standard of care (meaning no chemo) for early her2+ bc.

That's one great drug!!!

Jan

Joni0702
Joined: Nov 2007
Posts: 128
Sep 7, 2008 07:53 pm Joni0702 wrote:

jan125 - do you know of any trials for Herceptin as stand-alone treatment?  

DEAK95
Joined: Apr 2006
Posts: 139
Sep 7, 2008 08:51 pm, edited Sep 7, 2008 08:52 PM by DEAK95 DEAK95 wrote:

Most doctors will say that Herceptin is your chemotherapy (chemical therapy) but it is actually  a mono-clonal antibody treatment for the Her2-neu+ protein in patients with + tumors since it attacks only these cells to stop them from replicating and spreading. I guarantee you she is also on some anti-estrogen drugs like arimidex or aromasin, etc... even if she has had a hysterectomy since the adrenal glands still produce estrogens, even after menopause. The Stand up for Cancer show was a nice surprise to see on TV. I've also been on Herceptin Weekly for 2.5 yrs and my Bone Mets have shrunk to stable.  Pat

DianaT
Joined: Jul 2008
Posts: 121
Sep 7, 2008 09:09 pm DianaT wrote:

Here are some links with a bit of info for the vaccine:

http://www.springerlink.com/content/tj451863035u3132/

http://cat.inist.fr/?aModele=afficheN&cpsidt=20145290

http://jco.ascopubs.org/cgi/content/abstract/23/30/7536

If you google E75 Her2+, you should be able to find additional information.  I am not sure if only people in the armed services can get into the trial, but I know the armed services are spearheading the trials.

Looks very promising to me and I am ready to get the vaccine!

Diana
Dx 1/7/2008, DCIS, 2cm, Stage IIIc, Grade 3, 16/27 nodes, ER-/PR-, HER2+
ango74
Fort Worth, TX
Joined: Jul 2008
Posts: 34
Sep 8, 2008 01:24 pm ango74 wrote:

I just had my first onco appt. after my surgery today.  I signed up to do a study that adds Avastin with the Herceptin but I will also be getting my regular chemo too.  I wonder if this is the same as the E75 trail, I will have to ask.  Sounds promising though.

Dx 7/18/08 3cm IDC, grade 3, er-/pr-, HER2+++
HensonChi
Joined: May 2008
Posts: 170
Sep 8, 2008 03:01 pm HensonChi wrote:

I was in the trial with avastian, but once they found out I needed herceptin they said I couldn't be in the trial anymore, as it is not for people with the her/neu thing.


Dx 2/22/2008, ILC, 1cm, Stage IIa, Grade 2, 1/14 nodes, ER+/PR-, HER2+
cheryl58
OH
Joined: May 2006
Posts: 537
Sep 8, 2008 03:29 pm cheryl58 wrote:

Brenda,

Thank you so much for the link.  I missed the show because we had out-of-town company.  I just sat here and had a darn good cry for an hour but feel very hopeful and enpowered since watching this very uplifting and inspiring show.  Thanks again!

Cheryl

Bilateral mast/no recon; 4 rounds of AC, tamoxifen
Dx 5/15/2006, ILC, <1cm, Stage I, Grade 1, 0/4 nodes, ER+/PR+, HER2-

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