Topic: Tamoxifin verses Evista for LCIS
- Posted on: Aug 14, 2009 03:34 pm
Joined: Mar 2009
Posts: 21
Hello LCIS Sisters. I am 54, diagnosed with LCIS in April. Just had appointment with oncologist and he recommended Evista instead of Tamoxifin. I am postmenopause but it seems that almost always Tamoxifin is suggested first with a diagnosis of LCIS. Just wondering if any other post menopause LCIS ladies were given Evista first. I know I have read the studies that say Evista is as effective as Tamox in preventing invasive breast cancers, but is it as effective for those of us with just LCIS? I just want the drug that will give me the most benefit, my gyn seems more in favor of tamoxifin, even though originally she suggested Evista first. She does agree that Tamoxifin seems to be the drug most often given for LCIS. Any input is greatly appreciated!
Kris
Dx LCIS, , Stage 0, / nodes
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leaf Joined: Dec 2005 Posts: 5,944 |
Aug 14, 2009 04:31 pm
leaf wrote:
http://www.ncbi.nlm.nih.gov/pubmed/19213563 - this, as usual, clumps all the higher risk patients together - but in the abstract they don't talk much about the LCIS patients alone. Maybe the total article does. If you're going through hell, keep going-Winston Churchill
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Krisc Joined: Mar 2009 Posts: 21 |
Aug 14, 2009 05:53 pm
Krisc wrote:
Thanks Leaf, you always have so much good information. Sounds like it is as effective for invasive but not so much for developing a non invasive. I did call and leave a message with the oncologist to tell him I was torn, I am sure he will get back to me soon. Are you on any preventive drug? Dx LCIS, , Stage 0, / nodes |
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awb Joined: Aug 2005 Posts: 2,764 |
Aug 15, 2009 01:02 am
awb wrote:
Krisc----I took tamox for 5 years for prevention, and am now taking Evista for further preventative measures. When I became post menopausal (immediate surgical menopause), I asked my oncologist if I could switch to Evista and he said no, that he wanted me to finish up my full 5 years of tamox first, since it was tried and true. They are supposed to be equal in preventing the invasive bc's, but tamox is better at preventing non-invasive bc's than Evista. (Although it is invasive bc that I am most concerned about, I'm glad to know the tamox also helps prevent DCIS as well). The studies with Evista are up to 8 years, but my docs say I may be able to take it indefinitely. It's a bit of a trade off----tamox has more risk of serious SEs but is more beneficial overall; Evista has less risk of SEs, but also less benefit overall for prevention. Anne Anne "I don't know what the future holds, but I know who holds the future"
Dx 9/5/2003, LCIS, Stage 0, 0/0 nodes |
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leaf Joined: Dec 2005 Posts: 5,944 |
Aug 15, 2009 05:49 pm
leaf wrote:
I'm on tamoxifen. I started it 7-06, so I have 2 more years to go. I was just officially pronounced postmenopausal. If you're going through hell, keep going-Winston Churchill
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LadyC Joined: Aug 2009 Posts: 2 |
Aug 15, 2009 11:20 pm
LadyC wrote:
Hi Krisc, I have been taking Evista (Raloxifene) since mid-2005. Currently I am postmenopause and hmm age 63  . I had a breast reduction mid-2005, and that's how my plastic surgeon found out that I have LCIS in both breast (age 59). I called a friend of mine who is is a breast oncologist with a very large teaching hospital in NYC. She said that there are many serious side effects with Tamoxifin, and since I was borderline osteo, that she recommended Evista for me and to take for 5 years. She had also said that with LCIS it was as effective as Tomoxifin. I see her and my breast surgeon every 6 months. I also have a mammo every 6 months, and will begin getting a sono every 6 months too. I hope that this is helpful.Dx 3/5/2005, LCIS, , Stage 0 |
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Krisc Joined: Mar 2009 Posts: 21 |
Aug 16, 2009 09:43 am
Krisc wrote:
Thank you for your post Lady C. That does help me to feel better about the Evista. Do you not have MRIs? I know there is some questions with the oncologist and breast surgeon as to yearly MRIs or not. Dx LCIS, , Stage 0, / nodes |
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yvonnew Joined: Nov 2009 Posts: 1 |
Nov 5, 2009 10:14 am
yvonnew wrote:
Hi ladies. I was diagnosed with LCIS in Sept. After careful deliberation, research and discussion, I decided to go on the Evista med instead of Tamoxifen because I was told that the difference in the benefits of two drugs was very minimal (one was .21 more effective versus .15 according to the STAR report). A very slight difference as you can see. Evista boosts bone strength and has less SE than Tamoxifen. I started taking Evista 2 weeks ago and have to continue for 5 years. I am post menopausal at 48 years old. My current monitoring is an MRI every six months, with a Mammo every six months (ie I will have a Mammo in Jan, MRI in Mar, Mammo in June, MRI in Sept) for the first year. If all is unchanged by next Sept, the doc suggested alternating MRI with Mammo for the next couple of years (ie MRI in Sept, Mammo in March, MRI following Sept, Mammo follwing March). Hope this was helpful. Diagnosis: 9/21/2009, LCIS, Stage 0, 0/0 nodes |