Topic: Ki-67 95%

Jul 23, 2009 10:42 PM fightinhrd123 wrote:

Mine was high too, chemo loves to kill fast mutiplying cells, I had chemo first and not one cancer cell left, and i had at least 2 pos nodes, probably four, so i dont look at my ki67 being high as a bad thing :) 

Jul 24, 2009 11:46 AM, edited Jul 24, 2009 11:49 AM by lookingforward4more

I just want to say that its a great sign that your nodes were negative. I had Grade 2 and 1 cancer with Ki-67 of 3% and 5% (two tumors in right breast) and also had two positive nodes. My point in telling you this is simply that even with excellent "pathology" my cancer spread to the nodes and yours did not which is a GREAT thing! Keep thinking positive thoughts and fight hard now. Chemo works much better on higher Ki-67 from what I have learned so the medicine is going to help your treatment! You can have a full recovery!

Jul 28, 2009 04:49 PM EllenWeav wrote:

we may be twins....my Ki-67 is 98%....same thing, when my oncologist said "this is the fastest growing tumor I've ever seen"..didn't help me much considering he is now retired and a world reknown breast cancer specialist.....I too had no node involvemnet. I was dx Jan of 08...my new oncologist wants to do preventitive chemo again in 2 yrs...I am doing it, because chemo does work great against the aggresive cells....I am clean and clear right now....triple negative as well..would love to compare notes with any others who are triple negative.

 Hope & Friendship to ALL

Aug 10, 2009 09:36 AM thenewme wrote:

Yikes! I just looked at my path report and mine shows Ki-67 = 100% - is that even possible?  I'm triple negative too,and my tumor grew super fast (now I know why!)

Aug 27, 2009 11:06 AM angelsabove wrote:

bump

Aug 27, 2009 12:37 PM weesa wrote:

My ki-67 was very high when I was diagnosed almost seven years ago. It was expressed as "two plus" on my path report. Yet my mitotic rate was only a "1". Never could understand if this is a contradiction. Onc never seemed concerned about ki-67, though. Just recently I had oncotypedx and it came back an 18. I am stage 3a grade 2, er, pr+ her-2 neg.  Had dd chemo, rads, mastx, AI's. Still Ned.

This brings me to another thought--since my joining here I have been struck by the number of members like myself, who don't understand their path report or who at least have some major questions about it. I have had stuff haunt me for years. I go to all the "Understanding your path report" type of websites and they are so general they don't give me any insight into mine. I would love to hear from anybody who really understands her path report and let me know how the heck you accomplished this. We seem to be a group of intelligent well informed women who are always on the prowl to learn more--yet this seems to be a common theme for us. Too bad--we shouldn't have to live with mysteries like this.Can't everything be reduced to lay terms? Would love to hear from you guys who share my frustration.

Aug 29, 2009 09:10 PM fairy49 wrote:

Weesa! isn't it so frustrating??!! It has taken me nearly a year to figure out my path report, to the point that I think I know it better than my onc! LOL!! I took every single thing on the path report and googled it until I found out what it meant, once I found out what it meant I continued to research to find out exactly what the score meant and so on, it was painful and scary, because I would get results, have no one to ask, and freak myself out! So now I know my path report inside out backwards, do I understand it totally, not yet, but am working on it! I stun my doctors with some on my questions, they give me this deer in the headlights look, I don't think they know that much about the total path report either, I think they have the certain things they look at, and thats that, so sad that we have to figure this all out ourselves!  The good thing is, that we can help others that come to this site looking for answers, hopefully....

L

ox

Aug 30, 2009 02:34 PM fairy49 wrote:

Weesa! you sound like me with the french thing LOL!! made sense to me! teehee!!

I have my path report in a file and its so worn out as I pull it out all the time! shish!! such a friggin pain in the ass to have to learn it all yourself, however, knowledge is power, so I am glad I have learned so much, but still so much to learn! I think I have the big stuff down, but I still pick it to pieces!

L

ox

Aug 30, 2009 04:04 PM hrf wrote:

What is Ki-67?

I have never heard of it and don't know what it means.

Sep 1, 2009 04:46 AM queenlurker wrote:

weeza, Agonized over my path report yesterday.  Seems like I can find something new everytime.

Found a pathology site which said that if a tumor was hormone neg to expect Ki-67 to be 50-90, good thing for me because mine was 87.

casey

Sep 20, 2009 05:41 PM MsBliss wrote:

My ki67 was 90% on biopsy, 70% on lumpectomy, also triple negative.  My doctor felt that my tumor was only 6 to 12 months old, which is probably why I had neg nodes too.  Did your report say anything about medullary features?