tracey2424

well here i am went for my chemo today been on Gemzar/cisplatin and onc says that as my Liver enzymes are too high and he has a gut feeling the chemos not working that i cannot go onto anymore chemo, my next one was going to be Navebline but he says i cant have it, or should i put it that i could have it but maybe go into liver failure.

after speaking to another patient she had been on the same regime as me and was taken off due to scans showing it had not worked but she had all the same symptoms as me high liver tests , swelling etc.

as you can imagine i came out feeling absolutley gobsmacked even more so as i feel very well in myself, so im going to go to the Royal Marsden in London for a second opinion i cannot give up yet i have two kids who i cant look in the face at the moment as my heart is breaking. 

I was on Herceptin only up until christmas and had been for 11 months and just because i waited for a clinical trial to start then to be told i couldnt enter due to being on Herceptin i have just deteriorated with the Liver Tests.

Tracey. 

I am on Cis[platin /Gemzar and having an absloute nightmare, i look about 5 month pregnant and all my ankles have swollen im exhausted, and cant imagine myself ever feelimng the same again, ive also had constipation so took a stoll softner and as soon as i stop taking them im constipated again.

im beginning to think this chemo does not agree with me and im guessing its the Gemzar rather than the Cisplatin, as i have Liver mets and its supposed to be hard on the liver.

Anyone else suffered with this ive read on another thread that you can suffer with a sore throat etc, believ me id rather have the sore throat.

Tracey. 

Hi Ladies

Do any of you ladies get a distended stomach after your chemo? its now been ten days since my chemo and i still feel and look about 4 month pregnant, chemo does cause me to get constipated so i have finally taken a stool softner which has eased a bit but my stomach and upper abdo has been rock hard for days.

Any Advise....

Tracey. 

Hi Ladies

Not been on the boards for a while had a real hard time latley, some may remember i turned yellow and my eyes turned an awful shade of green,so started Cisplatin/Gemzar had round 1 my chemo day is Tuesday and by Saturday was admitted to the hospital my Bil was at its highest was 238, i was discahrged on the Tuesday and asked to go back for my next 3 week cylce to see if my counts had come down, by the friday of the second week my colour was going down and beginning to feel better, when i went back for round 2 much to my oncs suprise my counts had turned a corner and come down to 168 so i had my second round of chemo last Tuesday.

By Saturday the same thing had happened counts rose and turned yellow i have been to see him today and he is saying to me that the only option left is Navebline/Cisplatin and he really isnt sounding very positive i feel sooo down tonight and have done for the past couple weeks.

im really thinking of going for a second opinion .

i suppose what i want to know is has anyone else had good results with Navebline/cisplatin.

i am Her 2 +++ and been on A/C,Taxotere, (Xelodia/ Herceptin which i had great results with for 10 month ) now Gemzar /Cisplatin.

love Tracey. 

Hi Luann

He got the results why iwas there it didnt start chemo until he had results, after seeing them he lowered the dose of Gemzar due to the effect on the liver and gave me the normal required dose of Cisplatin.

Tracey. 

Hi all

i posted last week due to my eyes being yellow and itchy skin, well i started my chemo Tuesday Gemzar /Cisplatin and there still as yellow am i being impatient as this is freaking me out i look awful, since having Liver mets for the last two yrs i have never had this, i know one of my enzymes was elevated and the onc reduced the dose of the Gemzar until hopefully my enzymes come back to the normal range.

i feel so paranoid .....

Has anyone else experienced this the onc never commented on them when i saw him Tuesday, im currently doing Gemzar/ cisplatin wk 1 and Gemzar alone wk 2 and wk 3 off.

Tracey. 

Hi All

Just got back from seeing my onc and my new regime will be Gemzar and Cisplatin, has anyone any experience on this?

i have to say when i hear the word Gemzar i immediatley thought of Denise our Gemzar queen its just the Cisplatin im not very knowledgeable on...

Im due to start this 25th March after 11 month on Herceptin only.

any advise on this cocktail would be great.

Love Tracey. x 

Hi Ladies

i would be intereSted to know how many ladies have taken Herceptin and it has failed after a short time, i have mets to the Liver that have progressed so onc has taken me off it and switched me to Gemzar, i am gutted as Tykerb is not yet licensed here in the UK. 

Love Tracey. 

well today i finally got my Trial info through, after my last scans in January my liver mets showed progression as I had been on Herceptin only for the past 10 month.

Had my last Herceptin on 3rd Feb and then had to be off all treatment for 5 wks to enter the trial.(which has been scary no treatment) The new drug in the phase 3 trial shows promise and has been used for a variety of cancer chemos with good responses, so its now being tryed for Breast.

Its called Eribulin and im due to start next tuesday this is an IV in the arm on Day 1 and Day 8 then two wks offand so on.

Apparently this drug is due for release early 2010.

Hoping this is as easy for me as the Xelodia was.

Love Tracey 2424 uk.xx 

Hi 

I was diagnosed in May 06 with mets to the Liver, I had A/C, then Taxotere then went onto Xelodia, i have been well throughtout, no pain, sometimes get a heavy feeling near my rib cage but sometimes think its mind over matter with me.

Managed to work look after my two kids lifes not changed really.

Also hello to the UK ladies (Sue + Pinkdove) not very many of us uk ladies on here.

Love Tracey.