Hi all,
Well, I think I know what caused my breast cancer. I just read the study at the link below. I wonder if anyone else is triple negative, and also received radiation "therapy" to the breast for a benign condition when she was a young adolescent?
http://envirocancer.cornell.edu/factsheet/physical/fs52.radiation.cfm
Hugs to all,
Annie
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TenderIsOur
Joined: May 2007 Posts: 2919 |
May 12, 2008 02:26 pm
TenderIsOurMight wrote:
It cannot be emphasized too strongly that treatment of each patient is a highly individualized matter. (FDA-approved labeling for warfarin (Coumadin) NDA 9-218/5-105)
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otter Joined: Jan 2008 Posts: 1733 |
May 12, 2008 02:35 pm
otter wrote:
Wow, Annie--nice article! I read your question on another thread, but I didn't answer (or I don't think I answered--chemo brain, you know) because I didn't have any specific information. I figured, of course irradiation can increase the risk of cancer; but would it increase the risk of BC specifically? I didn't know. I also was surprised to read about the radiation treatments you received for a benign condition (a cyst?) during your teen years. My goodness! What were they thinking? It reminds me of my youth, when one of the local shoe stores had a podium-shaped device into which you stuck your feet while wearing a pair of shoes. Push a button, and a screen on the top of the device would show whether the shoes were too tight: You could see the bones of the feet, encased within the shoes. Guess how that image was created. Anyway, you might have found a lead on the cause of your BC. OTOH, I did see this in the article you posted: "The linear relationship of radiation dose and breast cancer risk does not extend to the highest radiation exposures, such as those which might be experienced following therapeutic treatments. The risk of subsequent breast cancer from very high doses is lower than that which might be expected from the effects of lower doses. This is because radiation at high doses is an effective killer of cells and dead cells are not able to develop into cancer. There are several other observations of interest: if the total radiation dose is split into many smaller doses, the risk of radiation-induced breast cancer is nearly the same as if the dose were given all at once. However, it may be that these smaller doses have to be given during a relatively short period of time. Recent studies of infants treated with radiation suggest a reduced risk of radiation-induced breast cancer when the exposure is delivered gradually over time." So, maybe ... or maybe not. I wonder if anyone else had an experience similar to yours. otter Dx 1/14/2008, IDC, 1cm, Stage I, Grade 2, 0/3 nodes, ER+/PR-, HER2- |
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SLH Joined: Oct 2007 Posts: 509 |
May 12, 2008 02:43 pm
SLH wrote:
Annie, I think you need to watch your thyroid because of the exposure also. My dad was about 10 when 3 of his siblings had TB. He had x-rays every 6 months for years. He never had TB, but he got thyroid cancer which metastasized to his lungs. Thyroid c is strongly linked to radiation exposure. It's one of the easiest cancers to cure if it's caught early. I think my bc was from working with paint thinners and benzene products. To clean up after oil painting we would wash our brushes and hands in toxic chemicals, and as a graphic designer I would clean my desk and art with benzene. I wonder how many artists have bc? sally |
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AnnNYC Joined: Aug 2007 Posts: 1480 |
May 12, 2008 02:48 pm
AnnNYC wrote:
Wow, Annie -- that article certainly seems to dovetail with your experience.
Otter, I remember those foot store x-ray machines -- and I remember my mother being x-rayed during her third pregnancy to see if rapid growth meant twins. Scary, how fast-and-loose people were with x-rays in the 1950s. Dx 3/9/2007, IDC, <1cm, Stage I, Grade 2, 0/5 nodes, ER+/PR+, HER2- |
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lvtwoqlt Joined: May 2007 Posts: 2267 |
May 12, 2008 03:03 pm, edited May 12, 2008 03:04 PM
by lvtwoqlt
lvtwoqlt wrote:
Anne, this brings up a question that I have had since my dx. From the time I was 8 until 12 (1969-1973) I was being treated for spine scolosis, and had numerable x-rays to check the progress of my scolosis and if the surgery I had at age 11 helped stablize my crooked spine. No one can give me a straight answer if that radiation I received those years could have effected my body and caused the abnormal mammo/biopsies I had prior to my bilat mast last June. It is something to think about. Sheila We are like tea bags, we don't know how strong we are until we were thrown into hot water. Eleanore Roosevelt
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Shirlann Joined: Feb 2002 Posts: 6058 |
May 12, 2008 07:42 pm
Shirlann wrote:
Hi honey, not me. Nothing, except I spent some time looking at my toes in the 50's in the x-ray machine in the shoe store!
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NancyD Joined: Feb 2008 Posts: 769 |
May 12, 2008 08:50 pm
NancyD wrote:
Sally, I have often thought there was a direct connection between my bezene use and my bc. As a graphic designer from way before we used computers, there was bezene in the rubber cement and thinner we used for paste-ups. Shoot, I used to squirt the thinner onto my hands to clean them of the residual stickiness. Did you have any chemo? Because now my worry is that I will develop another cancer down the road due to the bezene exposure and the Cytoxan I have been taking. There's a definite correlation there that's in the side effects literature. Annie, I don't have triple neg bc, and I also did not get many xrays growing up (except dental checks), but I think there are some definite environmental connections that will need to be explored more. I'm sure many of them have been mapped already and are just waiting for the right eye to put them together. |
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carolsd Joined: Sep 2007 Posts: 191 |
May 12, 2008 09:51 pm
carolsd wrote:
I've always wondered if the radiation treatments I received for my acne contributed to my BC. I would lie on the cot with my chest totally exposed, while my face was irradiated. I think it may have been a causative factor. Dx 9/22/2004, IDC, <1cm, Stage I, Grade 2, /0 nodes, ER+/PR+, HER2- |
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Shirlann Joined: Feb 2002 Posts: 6058 |
May 15, 2008 06:03 pm
Shirlann wrote:
This is an interesting thread, with many truths in it. But it pays to remember that they have found breast cancer residue in Egyptian mummies. So who really knows? Hugs to you all, Shirlann |
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HeatherBLoc
Joined: Dec 2007 Posts: 801 |
May 16, 2008 02:48 am, edited May 16, 2008 02:48 AM
by HeatherBLocklear
HeatherBLocklear wrote:
Hi to all, Yes, it is interesting, and perhaps elucidating, to speculate on causative factors if they don't make us feel guilty. The reason I zeroed in on this particular cause is because I have a type of breast cancer (medullary, triple negative) usually found in much younger women, and very often associated with the BRCA mutations. In fact, my oncologist was convinced my test would come back positive, and was totally nonplussed when it did not. When I told him I'd had nuclear radiation to the breast over a six-week period as a very young adolescent, he ventured that this alone, and especially in conjuction with a lumpectomy, might well be at the origin of a basal-cell cancer which is a direct result of DNA alteration. I know that I am totally convinced. Whether or not I'm right really don't mean much except, perhaps, it might lower my chances of getting a similar cancer in the other breast. I don't know; this is all mere speculation. Hugs from North Africa to all (I'm back here packing up my stuff between two chemo treatments). Annie |
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otter Joined: Jan 2008 Posts: 1733 |
May 16, 2008 04:18 pm
otter wrote:
Annie, you snuck off to Africa without telling us??? (Well, you probably know what we would have said. Did anyone accompany you, to help you pack?) I know what you mean about being totally convinced of the cause of your BC, if for no other reason than the fact that it allows you to worry less about the other side. Every time I read a new report about what causes--or prevents--BC, I cringe. It seems another report comes out every few days, and it's too late for me to do anything about most of them. The latest is that stuff out of Portland, Oregon, claiming that women who develop BC while taking HRT are less likely to die of their cancer than women who develop BC but never took HRT. Great. So I adopt one truly helpful preventive measure (not taking HRT), and develop BC anyway; and now I find out I might have been better off on HRT??? There must be more to that story... Anyway, pack carefully, fly safely, and we'll see you on the other side. I hope you come back soon, although this must be a nice respite for you. Hugs, otter Dx 1/14/2008, IDC, 1cm, Stage I, Grade 2, 0/3 nodes, ER+/PR-, HER2- |
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AnneW Joined: Oct 2002 Posts: 1953 |
May 16, 2008 04:19 pm
AnneW wrote:
Amazing stuff, Annie. I'll bet you're right on target with this theory. Glad to know it wasn't the alcohol or the tofu. Or whatever. I'm thrilled you're strong enough to be back in Camel Land to get your stuff. Watch out for those turds. Hugs, Anne 2002 IDC stage 1, grade 1, rads & AI
Dx 9/18/2007, ILC, <1cm, Stage I, Grade 1, 0/1 nodes, ER+/PR+, HER2- |
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Shirlann Joined: Feb 2002 Posts: 6058 |
May 16, 2008 06:29 pm
Shirlann wrote:
Oh Annie, how did I miss you were a Medullarian? ME TOO!!! They thought I had Lymphoma. Idiots. It is fun we are both Medullary and both Triple Negs. We are truly, truly sisters. Hugs, Shirlann |
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