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Topic: Chemo Dose Dense vs Standard Dose

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Joined: Nov 2007
Posts: 32
  • Posted on: Mar 29, 2008 05:38 pm
Sig wrote:

Hi fellow canadians, looks like that dose dense (every two weeks) regimen is more common in the US than in Canada. I'am curious to see if you girls have/had dose dense (every two weeks) regimen or the standard regimen (every three weeks).  Is anyone also know when dose dense would be recommended? I had 4 cycles of AC every three weeks and 4 cycles of taxol every three weeks and now on Herceptin for a year.

Sig 

Posts 1 - 9 (9 total)
Sierra
Joined: Feb 2004
Posts: 4627
Mar 29, 2008 05:46 pm Sierra wrote:


Hi Sige:

I had every 3 weeks approx

4 ac
4 taxol .. 4 hour infusions

Best to you!


Hugs, Sierra

:))

The time is NOW!
roberta37
Joined: Mar 2008
Posts: 137
Mar 29, 2008 09:14 pm roberta37 wrote:

I'm reading Dr. Marla Shapiro's book right now and she was treated in 2004 and her treatment included dose-dense chemotherapy.

I have yet to see the oncologist but will definitely ask him if that is an option for me. I'm very healthy otherwise and I really feel taking an aggressive approach to this is the route I need to go.


Dx 2/23/2008, IDC, 3cm, Stage II, Grade 3, 3/5 nodes, ER+/PR+
linda447
Joined: Jan 2007
Posts: 7
Mar 29, 2008 10:39 pm linda447 wrote:

Hi Sig

I had dose dense, 4 ACand 4 Taxol every  two weeks due to a very aggressive tumor along with being Triple Negative...my oncologist is from Sudbury. Best of luck.


Dx 2/5/2006, IDC, 4cm, Stage IIIa, Grade 3, 5/5 nodes, ER-/PR-, HER2-
mke
Joined: Sep 2007
Posts: 203
Mar 30, 2008 10:40 am mke wrote:

I had dose dense AC and taxol in 2006 at Princess Margaret in Toronto.  I don't know the criteria they used, but it was my second round of BC (HR/PR- Her2+ this time) and the docs' thought that it was a good idea to treat this round "agressively".

I had a good response to the treatment in that the tumour shrunk to nothing, but it was very hard on me - hospitalized twice, IV antibiotics and blood transfusions.  And I still have neuropathy in my hands and feet.  I was 60 at the time, it might be easier on a younger woman.

lisa39
Joined: Feb 2008
Posts: 90
Mar 31, 2008 09:54 am lisa39 wrote:

Hi Sig,

I was noticing the same thing re: dose dense being more common in the U-S.  I'm glad you started this thread.   

I'm almost halfway through 4 AC, 4 Taxol.  I'm a once every 3 week girl.

Receiving treatment at Princess Margaret Hospital in Toronto.


Dx 11/29/2007, IDC, 1cm, Stage I, Grade 3, 0/4 nodes, ER-/PR-, HER2+
Sig
Joined: Nov 2007
Posts: 32
Mar 31, 2008 09:51 pm Sig wrote:

Hi Lisa, I think it might have something to do with ER/PR- and node positive (in Canada). If I knew more about all this prior to the start of my treatment I would asked to my oncologist but at the time of my diagnostic I did not know anything about chemo. May be someone will shed some light. I guess you will also get herceptin as you are HER+. I am receiving my Treatment at the Ottawa Cancer Center. Best of luck to all.

Sig

cbr2004
Joined: Jul 2004
Posts: 327
Apr 1, 2008 12:25 am cbr2004 wrote:

It is my understanding that there have not been clear indications that dose-dense give better or worse statistics than the 3-week protocol.

lisa39
Joined: Feb 2008
Posts: 90
Apr 1, 2008 10:01 am lisa39 wrote:

Sig -- yes, I'll be getting Herceptin too - after 21 blasts of radiation post-chemo.   Fun times - not!!  But I sure am glad Herceptin exists for us HER-2 positive gals.  I bet you are too. 

I think I'll ask my oncologist about the prevalence of dose dense treatment in the U-S at my next appt - which is April 11th.  He might have some info I can share with the group.

Cheers, Lisa  


Dx 11/29/2007, IDC, 1cm, Stage I, Grade 3, 0/4 nodes, ER-/PR-, HER2+
wetcoast
Joined: Jan 2008
Posts: 167
Apr 1, 2008 10:54 am, edited Apr 1, 2008 10:55 AM by wetcoast wetcoast wrote:

I am doing dose dense ac and taxol. I just finished the ac. I was told I was in good shape and my body could handle it. I am triple neg. From BC, Canada

dx dec 11/07 1.7 cm stage 1 grade 3 er pr her neg, lymph node neg

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