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Topic: Any Her2+ With Low Oncotype DX Score?

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Joined: Mar 2008
Posts: 569
  • Posted on: May 11, 2008 07:16 pm
Dejaboo wrote:

Just what the Subject is asking.

Im hoping to find some Her2 + Low Score Oncotype DX ...Since I didnt have enough tissue to test.

I am wondering if it every happens.

If you did get a low #.  What was your stage & grade also.

Thanks,

Pam


Dx 3/7/2008, IDC, <1cm, Stage I, Grade 1, 0/1 nodes, ER+/PR-, HER2+
Posts 1 - 4 (4 total)
stacey2930
Joined: Oct 2005
Posts: 904
May 11, 2008 07:35 pm stacey2930 wrote:

Hi.

       my tumor was not Her2 + but it was a grade 1. My onc score was an 8.  I was told a grade 1 tumor is not common especially in younger women. I was 42 at the time. If I had to guess I would bet your oncotype score would be in the low range simply because your tumor is a grade 1.  Stacey

Dragonfly92…
Joined: Jul 2007
Posts: 82
May 13, 2008 09:18 pm, edited May 13, 2008 09:21 PM by Dragonfly92127 Dragonfly92127 wrote:

I had some confusing Her2 test results so we are going with positive.  My oncotype dx was a 9.  Onc said it is unusual for a low oncotype to be her2+.  I am stage 3a, grade 2.

Sue Ellen

1 Internal Mammary Node Positive - Her2 Status undetermined: polysomy of chrom 17 - Oncotype Score 9 - 4 AC, 12 weekly Taxol/Herceptian, 5 weeks Rads, Arimidex.
MAMHOP
Joined: Aug 2007
Posts: 596
May 13, 2008 10:38 pm MAMHOP wrote:

I am also not Her2+, but I am a stage 1 (.3cm), grade 1 pure tubular -- my Oncotype was in the low range, but was a 16 -- was actually much higher than what I expected for a low grade, tiny tumor and tubular is supposed to be favorable.

I did not do chemo, but would have liked my score to be lower, but it is what it is.

M.

findacure
Joined: Nov 2006
Posts: 62
May 13, 2008 11:44 pm findacure wrote:

I'd also like to add that I too, was dx with grade 1 tubular (had three pathologists read slides and readings ranged from "tubule like features", to "tubular" to "pure tubular"). My oncotype came back at 16 with a tumor size of 1.1 cm. I did not do chemo as well as it was not recommended and like Mamhop I would've loved a lower score. So how does this make any sense?

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