Topic: Natural Alternatives to taking Tamoxin?

Is there a copy of this diet somewhere? Sounds interesting!

My wife takes I3C, and so far so good.

Erick Carpenter

I am taking Dim, dandelion, milk thistle, a liguid multi-vitamin, green drink, Sam-E and fish, flax, borage plus upped the organic diet and stopped drinking tap water.  So far, so good.

I was just going to start a thread on this topic but then saw this.

I started Tamoxifen in Oct 07 and within' 6 weeks I broke out with a complete allergic body rash.  I am premenopausal and there for Tamoxifen is the ONLY estrogen blocker for estrogen recptive breast cancer in pre-menopasual women. 

My ono took me off for a few months and these are now my options:

1.  Have my overies removed...

2.  Have my overies radiated...

3.  Have my overies suppressed by a series of shots...

And that's it.

Therefore, I am screwed. 

My question is:

Is there anyone out there that is familar with any other treatments or ways to block estrogen other than Tamoxifen?  Believe me, I have researched lots.

I have been taking nothing for 6 months now.  My period has returned and so my body is flowing with estrogen.

What shoud I do?

Eric,

Can you tell me what I3C is???

I also was wondering about alternative treatments.

By the way, do you guys ride?  I am in northern CA north of Sac and use to ride a lot in the San Jose area.  Awesome!

Thanks for the response.

Here you go RobbinJaye, I3C.

http://www.lef.org/magazine/mag2002/jan2002_report_i3c_01.html

kind of an overview, and also a "versus" DIM. My wife uses I3C instead of Tamoxifen, and so far, so good. do a google on it and see what you think.

and yep, we ride around the San Diego area, made a trip last year to Yosemite, and want to go back to Sequoia.

Ride on!

Another study from Berkely (I posted this on another area here)

http://www.jbc.org/cgi/content/full/280/10/8756

I3C is a promising chemotherapeutic agent for treatment of human breast cancer, and other reproductive cancers, because of its potent growth inhibitory properties (18-23, 60-62), and repression of invasion and migration of cultured breast cancer cell lines (24). Elucidation of the molecular mechanisms and cell cycle targets of the I3C anti-proliferative signaling pathway provides critical information that could potentially be exploited in the development of novel indole-based therapeutic strategies. We previously documented that I3C induces a G₁ cell cycle arrest of human breast cancer cells that is accompanied by the dual inhibition CDK6 and CDK2 kinase activities (19). I3C and its natural dimerization product DIM (12) have been shown to inhibit CDK2 enzymatic activity, although the distinction in the mechanisms underlying the effects of these two indoles was unknown. We now establish a new and unique feature of the I3C signaling pathway by establishing that I3C induces a robust down-regulation of CDK2 kinase activity that is accompanied by selective alterations in the cyclin E composition, size distribution and subcellular localization of the CDK2 protein complex. Furthermore, we show that this mechanism of regulating CDK2 function is specific to the I3C anti-proliferative signaling pathway that is distinguishable from the actions of DIM and the anti-estrogen tamoxifen.

I've been researching on the tamoxifien alternative too...after I finish radiation my med oncologist will want me to start it.

I read an article on curcumin/turmeric ability to block estrogen mimickers;

source:

http://www.goodhealth.nu/News_Articles/050111-curcumin-anti-cancer-US.htm

this site talks about many neat things you can supplement after bc to help prevent recurrence:

http://www.raysahelian.com/breastcancer.html

I hope my med oncologist will agree to check my hormone levels and run the blood test that predicts if you are a good metabolizer for tamoxifen ;higher circulating estrogen levels increase chances of recurrence, even if you take tamoxifen...source:

http://www.medscape.com/viewarticle/571252

So far the things I've researched these three supplements have impressed me:

Turmeric/curcumin

flaxseed

CoQ10

I've googled Coq10 and flaxseed with tamoxifen and they seem to offer better effects when taken together.

Like any supplement or medication you have to remember every ones body is different and responds in different ways.

I still research and everyday I stand amazed at the things I learn!

good luck

God Bless

Chewyoug,

I changed my diet and stop my hot flushes. I did major changes so you may not want to try my diet, but my natural doctor told be NO sugar of any kind.  And it worked.  I don't know why?

FLALADY

Is 13C something that you can buy at a health food store? Is it in a vitamin form or what? thank you!