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Topic: physically depressed due to ai & OS shot?

Forum: Mental Health: Because Cancer Doesn't Just Affect Your Breasts — Meet and support others who are affected by these issues around anxiety, depression, and other emotional effects.

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Posted on: Jan 15, 2023 01:24PM

Posted on: Jan 15, 2023 01:24PM

ladyc2020 wrote:

after changing AI from letrozole to anastrozole I had I initially thought the side effects were more tolerable. However, it’s been about 9 months and I feel that robbing my body if every scrap of estrogen has brought me into an odd depression which seems purely physically and mental. I have zero motivation or energy to do anything. And I don’t seem to care either. I am tired to my bones as though I’m 40 years older. This is not me. I keep skipping my meds and when I do, I can actually some things done. Example - skipped Friday pill and Saturday I cleared out my garage. I then did absolutely nothing for the remaining 8 hours of the day ( the same zero energy or motivation) but at least I was better for a few hours.

I’m really struggling on this treatment. My cancer was 99% hormone positive so I feel it’s important to keep going. But I’m struggling hard and maybe only taking the pills 80% of the time now. I feel like I’m a 90 year old lady who just has no life left inside to do anything. It’s taken my vitality, my sexual health, my ambition. And seems to be getting worse. I’ve been laying in bed for 2hours and can’t find the energy to get out of bed. What the hell has happened to me?

Hormonal Therapy 2/28/2020 Femara (letrozole), Zoladex (goserelin) Dx 8/6/2020, IDC, Left, 1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Hormonal Therapy 8/21/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/18/2020 Lumpectomy; Lumpectomy (Left) Dx 9/23/2020, DCIS, Left, 2cm, Stage 0, Grade 1 Radiation Therapy 10/31/2020 Whole breast: Breast, Chest wall Hormonal Therapy Arimidex (anastrozole)
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Jan 17, 2023 06:10PM salamandra wrote:

From what you write, it sounds (maybe?) like fatigue more than depression.

Tamoxifen totally wiped me out. I got referred to a psychiatrist and we actually tried the med they give to people to narcolepsy to try to get some energy back. It didn't work for me, but apparently it does for others so it could be worth a try seeing what your clinic's psychiatric team has to offer.

I ended up find a different med that worked better for me (toremifene) but I consider myself really lucky. I do know people who really give every med a fair shot and their body just won't take it.

FWIW, your stats look similar to mine. I had pretty much come to the conclusion that if my choices were tamoxifen or nothing, I would do nothing and hope for the best. I could not live my life that way, I could not keep a job, I could not support myself. So it's not pathetic at all.

Dx at 39. 1.8cm. Oncotype 9. Dx 9/19/2018, IDC, Right, 1cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- Surgery 10/18/2018 Lumpectomy; Lymph node removal Hormonal Therapy 11/1/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 12/3/2018 Whole breast: Breast Hormonal Therapy 12/19/2019 Fareston (toremifene)
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Jan 22, 2023 05:17PM ladyc2020 wrote:

hey everyone, really appreciate all the responses. I thought I sent a long reply last week but turns out I didn’t submit.

Definitely feels more like extreme fatigue than depression. Will look at getting lab work. Am taking all sorts of vitamins already including b12.

Tomtom- yes it’s me ☺️☺️💕💕💕

Cant take tamoxifen.

Im grateful for all of you and your care and insight. So sorry I didn’t reply individually and I apologize for this short response.



Hormonal Therapy 2/28/2020 Femara (letrozole), Zoladex (goserelin) Dx 8/6/2020, IDC, Left, 1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Hormonal Therapy 8/21/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/18/2020 Lumpectomy; Lumpectomy (Left) Dx 9/23/2020, DCIS, Left, 2cm, Stage 0, Grade 1 Radiation Therapy 10/31/2020 Whole breast: Breast, Chest wall Hormonal Therapy Arimidex (anastrozole)
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Jan 22, 2023 05:24PM ladyc2020 wrote:

  • I’m currently reading this book. Very interesting. Fully aware that I would take all the drugs to extend my life however, if stage 4.



Hormonal Therapy 2/28/2020 Femara (letrozole), Zoladex (goserelin) Dx 8/6/2020, IDC, Left, 1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Hormonal Therapy 8/21/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/18/2020 Lumpectomy; Lumpectomy (Left) Dx 9/23/2020, DCIS, Left, 2cm, Stage 0, Grade 1 Radiation Therapy 10/31/2020 Whole breast: Breast, Chest wall Hormonal Therapy Arimidex (anastrozole)
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Jan 22, 2023 09:10PM gailmary wrote:

just read a blurb about low thyroid. No wonder I'm so miserable. My thyroid levels ARE LOW. Check that out too maybe.

Dx 11/25/2008, IDC, Left, 2cm, Stage IIA, Grade 1, 2/12 nodes, ER+/PR+, HER2- Dx 4/13/2017, Stage IV, metastasized to bone Radiation Therapy 5/24/2017 Hormonal Therapy Faslodex (fulvestrant), Femara (letrozole)
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Jan 22, 2023 10:40PM ladyc2020 wrote:

gailmary- oh gosh sorry to hear that. What’s the next step for you? And yeah, I do wonder if that’s why I have zero energy… next appointment is Feb 13th and will be asking

Hormonal Therapy 2/28/2020 Femara (letrozole), Zoladex (goserelin) Dx 8/6/2020, IDC, Left, 1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Hormonal Therapy 8/21/2020 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/18/2020 Lumpectomy; Lumpectomy (Left) Dx 9/23/2020, DCIS, Left, 2cm, Stage 0, Grade 1 Radiation Therapy 10/31/2020 Whole breast: Breast, Chest wall Hormonal Therapy Arimidex (anastrozole)
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Jan 22, 2023 11:49PM harley07 wrote:

@ladyc - just started reading the same book. About a quarter of the way through. I don’t agree with everything she’s written but most of it seems to align with my thoughts on the healthcare industry.

I hope you get a quick and productive resolution to your fatigue.

RAD51D mutation Surgery 11/5/2020 Lumpectomy; Lumpectomy (Right) Dx 11/10/2020, IDC, Right, <1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Surgery 11/20/2020 Lumpectomy; Lumpectomy (Right); Lymph node removal Radiation Therapy 1/8/2021 Hormonal Therapy 2/8/2021 Arimidex (anastrozole)

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