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All TopicsForum: Not Diagnosed With a Recurrence or Metastases but Concerned → Topic: Metastasis to thyroid?

Topic: Metastasis to thyroid?

Forum: Not Diagnosed With a Recurrence or Metastases but Concerned —

Meet others concerned about developing a recurrence or metastases.

Posted on: Jul 10, 2012 07:22AM

Laural wrote:

I had a PET scan yesterday and today my primary care physician called to order a thyroid ultrasound due to increased uptake in thyroid. I see my oncologist Thursday to further discuss the scan. Has anyone had experience with metastasis to the thyroid?

Dx 9/18/11; Stage 1 IDC on left, 1.2 cm. Grade 2, 0/2 nodes positive; Stage 1 ILC on right, 1 cm. Grade 2, 0/13 nodes positive; Acute leukemia as young adult and secondary MDS ever since. Through it all, God is faithful.
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Jul 10, 2012 09:51AM Heidihill wrote:

I just got back from my ultrasound ordered for the same reason. The doctor said it hadn't changed from the last time when they did a fine needle aspiration for biopsy tissue. It was benign then so he didn't feel the need to biopsy this time. I got myself psyched up for nothing. But I was happy! Hope your US and/or biopsy are benign too!

Dx 8/2007, IDC, Left, 2cm, Stage IV, metastasized to bone, Grade 2, 2/19 nodes, mets, ER+/PR+, HER2- (FISH) Hormonal Therapy 3/25/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jul 10, 2012 10:01AM pupmom wrote:

My first CT found some nodules on my thyroid. Follow-up showed the same nodules. MO said they were benign but could turn malignant (not bc related). Anyway, I am seeing an Endocrinologist now who will follow-up on these nodules indefinitely.

Life is what happens while we're making other plans. Dx 10/18/2011, IDC, 1cm, Stage IIA, Grade 1, 2/21 nodes, ER+/PR+, HER2-
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Aug 13, 2012 03:08PM wpolischuk wrote:

Man we really do suffer from the same type of things.

I had a CT scan of my chest and they found two nodules on my thyroid. I need ultrasound blah blah blah....

So I know how you ladies feel....

We need to keep on keepin on....

Wendy  

Dx 3/29/2004, IDC, 6cm+, Stage IIIA, Grade 3, 2/18 nodes, ER+/PR+, HER2- Surgery 4/1/2004 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right; Prophylactic ovary removal Chemotherapy 6/12/2004 Adriamycin (doxorubicin), Taxol (paclitaxel) Hormonal Therapy 2/15/2005 Aromasin (exemestane)
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Aug 13, 2012 03:59PM NancyD wrote:

I've had thyroid nodules since my mid-twenties, and in fact, they removed half my thyroid back then to see if it was malignant (fortunately, not). Every scan I've had for my breast cancer has mentioned the still apparent uptake in the remaining thyroid which has grown over the years. Still not malignant.

I'm not a complete idiot. Some parts are missing. Dx 2/22/2008, IDC, Left, Stage IIIA, Grade 2, 4/10 nodes, ER+/PR+, HER2- Chemotherapy 3/22/2008 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Surgery 7/11/2008 Mastectomy: Left; Prophylactic mastectomy: Right Hormonal Therapy 9/1/2008 Arimidex (anastrozole) Radiation Therapy 9/5/2008 Breast, Lymph nodes Surgery 1/28/2010 Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap
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Aug 16, 2012 10:04PM Mzmerz wrote:

When I had my "routine" scan that found the mets in my iliac crest, there was uptake on my thyroid, but after several imaging tests, they determined it was my thyroid gasping its last breath and fizzled out.  As explained by my thyroid doctor, when it has some kind of "trauma" it can light up on the PET.  I basically live in 275 mcg of Levothyroxine and I feel like it does nothing. Hopefully, it's nothing.  Good luck.

Dx 6/12/2009, IDC, 3cm, Stage IIB, 12/19 nodes, ER+/PR+, HER2- Surgery 7/8/2009 Lumpectomy: Right; Lymph node removal: Right, Sentinel Chemotherapy 8/7/2009 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 1/3/2010 Hormonal Therapy 2/22/2010 Surgery 5/8/2010 Prophylactic ovary removal Dx 3/22/2012, IDC, Stage IV, metastasized to bone, 12/19 nodes, mets, ER+/PR-, HER2- Radiation Therapy 3/27/2012 Hormonal Therapy 5/1/2012 Femara (letrozole) Targeted Therapy 7/15/2016 Ibrance (palbociclib) Dx 11/2016, IDC, Stage IV, metastasized to bone/liver, ER+/PR-, HER2- Hormonal Therapy 3/3/2017 Faslodex (fulvestrant) Chemotherapy 5/23/2017 Taxol (paclitaxel)
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Aug 17, 2012 03:43PM calamtykel wrote:

Don't know if this means anything, but after I had chemo, I found a lump at my collarbone that was moveable.  I had an ultrasound and when they did, they ultrasounded my thryoid (that was weird..)    The thing on my collarbone was just a benign reactive node (it was removed surgically) but my breast surgeon pointed out that some things were found on my thyroid but that "we all have them) - I can't remember what she said they were, and that I should consider following up in the future.   I haven't yet but just wanted to let you know that maybe lots of us have "stuff" on our thyroids.

I hope that yours turns out to be nothing! 

"But when he saw the wind, he was afraid and, beginning to sink, cried out, “Lord, save me!” Immediately Jesus reached out his hand and caught him. “You of little faith,” he said, “why did you doubt?” Matt. 14:28 Dx 6/12/2010, IDC, 1cm, Stage IIA, Grade 2, 2/12 nodes, ER+/PR+, HER2-
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Sep 30, 2012 04:24PM Laural wrote:

Praises that the 6 biopsies they took from my thyroid were all benign. Now it's just monitoring every 6 months to watch the nodules' growth as they are getting large. May still need surgery eventually but no cancer. Even my blood cancer has been quiet since the chemo for the breast cancer. It is nice to be at a healthy juncture for the first time in awhile.

Dx 9/18/11; Stage 1 IDC on left, 1.2 cm. Grade 2, 0/2 nodes positive; Stage 1 ILC on right, 1 cm. Grade 2, 0/13 nodes positive; Acute leukemia as young adult and secondary MDS ever since. Through it all, God is faithful.
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Sep 30, 2012 04:44PM mrsnjband wrote:

I was told that it isn't uncommon to have this happen.  I had a ultra-sound of my thyroid & the specialist said he thought everything looked fine but would do a biopsy if my MO thought it was necessary.  Never had it done & it has been almost 5 years with no problems.

Glad you hear your results were benign! NJ

Norma June, Bi-lateral MX 2008, Bi-lateral DIEP 2011 Dx 1/10/2008, IBC, <1cm, Stage IIIB, ER-/PR-, HER2- Chemotherapy 1/25/2008 AC Chemotherapy 3/10/2008 Taxol (paclitaxel) Chemotherapy 5/29/2008 Taxotere (docetaxel) Surgery 7/10/2008 Lymph node removal: Right; Mastectomy: Right; Prophylactic mastectomy: Left Radiation Therapy 8/11/2008 Surgery 8/15/2011 Reconstruction (right): DIEP flap Surgery 8/15/2011 Reconstruction (left): DIEP flap Surgery 12/12/2011 Reconstruction (left)
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Jun 9, 2017 06:04AM - edited Jun 9, 2017 06:12PM by marijen

Bump.


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Jun 9, 2017 06:07PM illimae wrote:

I was told I have inflammation and a thyroid nodule, an US was done and considered ok but it's being watched. I've read that breast cancer rarely metastasizes to the thyroid but it would seem that some tyhroid issues are common with BC.

Diagnosed at 41 Stage IV De Novo Dx 11/16/2016, IDC, Left, 5cm, Stage IV, metastasized to bone, Grade 3, 3/13 nodes, ER+/PR-, HER2+ (IHC) Targeted Therapy 1/1/2017 Perjeta (pertuzumab) Chemotherapy 1/2/2017 Abraxane (albumin-bound or nab-paclitaxel) Targeted Therapy 1/2/2017 Herceptin (trastuzumab) Surgery 6/26/2017 Lumpectomy: Left; Lymph node removal: Underarm/Axillary Radiation Therapy 8/10/2017 Breast, Lymph nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jun 9, 2017 06:12PM - edited Jun 10, 2017 03:44PM by marijen

I was told yesterday that breast cancer does not metastisize to the thyroid. This by a thyroid cancer specialist. I would like to find the info to send to my oncologist

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Jun 9, 2017 06:30PM avmom wrote:

I had a thyroid ultrasound and biopsy after scans done as part of my staging at diagnosis. The biopsy came back B9, but I will likely be monitored with annual ultrasounds to keep track of the nodules found. I have my 6 month visit with my MO next week, and will likely have an ultrasound scheduled again this year

My understanding is that lots of people have B9 thyroid nodules, but I have also seen reports of people having both breast and thyroid cancer.

Surgery 12/23/2014 Lumpectomy: Right Dx 1/7/2015, IDC, Right, 4cm, Stage IIA, Grade 3, 0/11 nodes, ER-/PR-, HER2- Dx 1/7/2015, DCIS, Right, 6cm+, Stage 0, Grade 2, 0/11 nodes, ER-/PR-, HER2- Surgery 1/12/2015 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right Surgery 10/19/2015 Prophylactic mastectomy: Left Dx 10/27/2015, LCIS/DCIS, Left, 6cm+, Stage 0, Grade 2, ER+/PR+ Surgery 5/24/2016 Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Surgery Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right Chemotherapy AC + T (Taxol)
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Jun 9, 2017 07:23PM marijen wrote:

Yes it's true you can have breast cancer and thyroid cancer but when they do the pathology do they find breast cancer cells inside the thyroid or is it other types of cancer? Breast cancer cells can be found in the liver bones brain andI think some other places when the breast cancer metastisizes

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Jun 10, 2017 03:40AM avmom wrote:

Marjen, the two people I personally know about had two primaries - the thyroid cancer was not mets

Surgery 12/23/2014 Lumpectomy: Right Dx 1/7/2015, IDC, Right, 4cm, Stage IIA, Grade 3, 0/11 nodes, ER-/PR-, HER2- Dx 1/7/2015, DCIS, Right, 6cm+, Stage 0, Grade 2, 0/11 nodes, ER-/PR-, HER2- Surgery 1/12/2015 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right Surgery 10/19/2015 Prophylactic mastectomy: Left Dx 10/27/2015, LCIS/DCIS, Left, 6cm+, Stage 0, Grade 2, ER+/PR+ Surgery 5/24/2016 Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Surgery Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right Chemotherapy AC + T (Taxol)
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Jun 10, 2017 03:30PM avmom wrote:

After breast cancer diagnosis, risk of thyroid cancer goes up

I found this article at science daily


Surgery 12/23/2014 Lumpectomy: Right Dx 1/7/2015, IDC, Right, 4cm, Stage IIA, Grade 3, 0/11 nodes, ER-/PR-, HER2- Dx 1/7/2015, DCIS, Right, 6cm+, Stage 0, Grade 2, 0/11 nodes, ER-/PR-, HER2- Surgery 1/12/2015 Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right Surgery 10/19/2015 Prophylactic mastectomy: Left Dx 10/27/2015, LCIS/DCIS, Left, 6cm+, Stage 0, Grade 2, ER+/PR+ Surgery 5/24/2016 Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Surgery Lymph node removal: Right, Underarm/Axillary; Mastectomy: Right Chemotherapy AC + T (Taxol)
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Jun 10, 2017 03:43PM marijen wrote:

Oh I just wrote a long note and forgot to submit. Sorry. Thanks for the article it's good. You are smart to watch your nodules. It's been 2years and 3 months since I was dx'd with IDC. They are watching mine too.

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Jun 10, 2017 11:46PM marijen wrote:

I decided to post the article. So both thyroid and breast are glands. I wonder what the correlation is with both getting cancer and yet not the same type of cancer?


Breast cancer survivors are at increased risk of developing thyroid cancer, especially within five years of their breast cancer diagnosis, according to a new analysis of a large national database. The study results will be presented Thursday at the Endocrine Society's 97th annual meeting in San Diego.

"Recognition of this association between breast and thyroid cancer should prompt vigilant screening for thyroid cancer among breast cancer survivors," said lead investigator Jennifer Hong Kuo, MD, assistant professor of surgery at Columbia University, New York City.

Breast cancer survivors, whose numbers are increasing, should receive counseling regarding their higher-than-average risk of thyroid cancer, Kuo recommended.

Until now, Dr. Kuo said, the relationship between breast and thyroid cancer has been controversial, largely based on single-institution studies that have suggested a possible increase in thyroid cancer incidence after breast cancer.

The researchers used the National Cancer Institute's Surveillance, Epidemiology, and End Results 9, or SEER 9, database to identify the number of individuals with a diagnosis of breast and/or thyroid cancer between 1973 and 2011. They found 704,402 patients with only breast cancer, 49,663 patients with only thyroid cancer and 1,526 patients who developed thyroid cancer after breast cancer.

Compared with patients with breast cancer alone, women who had breast cancer followed by thyroid cancer were younger on average when diagnosed with their breast cancer. They also were more likely to have had invasive ductal carcinoma (the most common type of breast cancer), a smaller focus of cancer, and to have received radiation therapy as part of their breast cancer treatment.

There was no difference in risk based on whether the breast cancer was hormone receptor positive or had spread to lymph nodes, according to the investigators.

Compared with patients who had only thyroid cancer, breast cancer survivors who developed thyroid cancer were more likely to have a more aggressive type of thyroid cancer, but the cancers were smaller in size and fewer patients required additional radioactive iodine treatment. Because thyroid cancer tends to occur at younger ages than breast cancer does, breast cancer survivors who then developed thyroid cancer were older on average than those with only thyroid cancer: 62 versus 45 years, respectively, Dr. Kuo reported.

The study findings showed that breast cancer survivors developed thyroid cancer at a median of five years. Therefore, Dr. Kuo recommended that every year for the first five years after a breast cancer diagnosis, especially survivors who received radiation therapy should undergo a dedicated thyroid exam.

Dr. Kuo said she plans to study whether tamoxifen treatment, typically given for five years after a breast cancer diagnosis, may play a role in increasing the risk of thyroid cancer.

Radiation therapy to the head, neck or chest is a known risk factor for thyroid cancer, according to the Endocrine Society's Hormone Health Network. Female sex raises the risk of both thyroid and breast cancer. The incidence of thyroid cancer is increasing, and Dr. Kuo said researchers must have a better understanding of the etiology for this increase.

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Jun 11, 2017 07:06AM pboi wrote:

I have had both breast and thyroid cancer. 4 months after my breast cancer diagnosis while undergoing chemo,I had a PET scan, and nodules were found in my thyroid. Biopsy confirmed thyroid cancer. Post chemo and radiation for my breast cancer, I had a thyroidectomy and radioactive iodine treatment for my thyroid cancer. I was told they were two primary cancers and unrelated, but since that time have seen some articles like the above suggesting a connection.

Chemotherapy 1/22/2014 AC + T (Taxol) Dx 12/10/2014, IDC, Right, 1cm, Stage IIA, Grade 3, 2/9 nodes, ER+/PR+, HER2- Surgery 12/26/2014 Lymph node removal: Right; Mastectomy: Right Radiation Therapy 7/6/2015 Hormonal Therapy 8/5/2015 Arimidex (anastrozole) Surgery 11/11/2015 Prophylactic mastectomy: Left; Prophylactic ovary removal
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Jun 11, 2017 07:55AM marijen wrote:

pboi did they tell you about the thyroid risks before radiation. I remember asking and they said it wouldn't hit my thyroid. I asked the specialist why no sheild and he said there was no scatter. I am still worried. I'm sorry it happened to you

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Jun 11, 2017 08:24AM - edited Jun 11, 2017 08:25AM by marijen

www.ncbi.nlm.nih.gov/pmc/artic... Hypothyroidism Resulting From Radiation

Thyroid iatrogenic sequelae can occur after the treatment of cancers, most notably pediatric malignancies. A late side effect of curative radiotherapy in the head and neck region is hypothyroidism. The pathophysiology of radiation-induced thyroid damage is multifactorial. Radiation inhibits follicular epithelial function and progressively alters the endothelium, resulting in cell degeneration and necrosis, follicular disruption and vascular degeneration and thrombosis, acute and chronic inflammation, fibrous organization, and partial epithelial regeneration [34, 35]. The cytotoxic β radiation released during iodine 131 isotopic decay directly damages the thyrocytes and small thyroid vessels and leads to atherosclerosis in larger vessels. Even though radiotherapy can result in several thyroid dysfunctions, primary hypothyroidism is the most common, occurring an average of 2–7 years after treatment, in a dose-dependent manner [16, 36, 37]. Several studies have demonstrated that the risk is proportionate to the dose of radiation, with neck, mantle, C2–T2 spine, brain stem, Waldeyer's ring and neck, supraclavicular and nasopharyngeal regions, and total body irradiation carrying the highest risk [3842]. The development of hypothyroidism in older breast cancer survivors is fairly common because a portion of the thyroid gland can be included in the treatment field; however, supraclavicular irradiation does not amplify risks. The incidence of hypothyroidism is as high as 30%–50% in patients treated with radiation for a head and neck malignancy or Hodgkin's disease [40, 41, 43, 44].

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Jun 11, 2017 10:24AM sbelizabeth wrote:

My thyroid function abruptly tanked right after rads. I'm convinced the extensive radiation, perhaps in conjunction with chemo, caused it.

pinkribbonandwheels.wordpress.... Dx 10/20/2011, IDC, Left, 1cm, Stage IIIA, Grade 2, 6/28 nodes, ER+/PR+, HER2- Chemotherapy 12/15/2011 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Surgery 4/18/2012 Mastectomy: Left Radiation Therapy 5/21/2012 Breast, Lymph nodes Hormonal Therapy 7/19/2012 Femara (letrozole) Surgery 4/15/2013 Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap
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Jun 11, 2017 12:10PM marijen wrote:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC39030...

Hypothyroidism After a Cancer Diagnosis: Etiology, Diagnosis, Complications, and Management

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Jun 11, 2017 01:54PM TB90 wrote:

I too have thyroid nodules but they were discovered a few years before I had radiation. My endocrinologist is very diligent in monitoring them. Started out every six months, then nine months and now I see him every year. They are not changing, so thus he seems less concerned. But he has been very reassuring that if there ever is a problem, thyroid cancer detected early, is very treatable. He was far more worried about the breast cancer for me. Research does show that thyroid nodules are very common. He did mention that he will continue to monitor due to the fact that I had radiation. I am glad . .. besides, he is very easy to look at.

SillyHeart

Dx 11/28/2013, DCIS, Grade 2 Surgery 12/18/2013 Mastectomy: Left Radiation Therapy 2/20/2014 Breast
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Jun 11, 2017 02:02PM marijen wrote:

TB90 thanks for the good news! I like the easy to look at part too.

Loopy

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Jun 14, 2017 06:46PM - edited Jun 14, 2017 06:49PM by pboi

marijen...i was diagnosed with my thyroid cancer prior to radiation for breast cancer i had my thyroidectomy about a week after chemo was completed and one week after that began radiation. my radiologist was aware of my thyroid cancer surgery and a shield was used in the area where my thyroid was

Chemotherapy 1/22/2014 AC + T (Taxol) Dx 12/10/2014, IDC, Right, 1cm, Stage IIA, Grade 3, 2/9 nodes, ER+/PR+, HER2- Surgery 12/26/2014 Lymph node removal: Right; Mastectomy: Right Radiation Therapy 7/6/2015 Hormonal Therapy 8/5/2015 Arimidex (anastrozole) Surgery 11/11/2015 Prophylactic mastectomy: Left; Prophylactic ovary removal

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