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Topic: Slightly Elevated CA 15-3 anyone out there had this

Forum: Not Diagnosed With a Recurrence or Metastases but Concerned —

Meet others concerned about developing a recurrence or metastases.

Posted on: Mar 14, 2019 02:28PM

Barteeellis wrote:

Hi I am so concerned. My Ca 15-3 has always been between 10-20. Six months ago they were 23.8 and I asked the MO and was told as long as not over 25 and they were unreliable. They have always done them so I guess there is some value to them. This appointment march 8th they were 32.5. I know that is a jump but still not far over the 25 which is what they cut off is. My MO said he could redo them in 2 months or if I was anxious he would order scans. Bone Scan and CT scan. My dear hubby told him it was all I was thinking about so I go next Wednesday for the scans and meet back with the oncologist on March 27th. He said there are a lot of false positives. I am 11 years our of Stge 2 A ER+PR+ . I have always had good reports until now. However when I had my breast reduction 4 yrs ago the pathology said no cancer but i had atypical hyperplasia in both breast. Please is there anyone out there that had elevated tumor makers that turned out to be nothing??? Would love to

Dx 7/7/2007, IDC, Right, 2cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2-
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Mar 14, 2019 04:42PM KBeee wrote:

There are many, many reasons tumor markers are elevated, most related to inflammation, etc. That is why most docs do not do them (though I secretly wish mine did...full disclosure). Do keep us posted.

Karen. Dx 8/5/2013, IDC, Right, 1cm, Grade 2, 0/1 nodes, ER+/PR+, HER2- (IHC) Surgery 8/26/2013 Mastectomy: Left, Right Chemotherapy 9/20/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 12/12/2013 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 1/23/2014 Reconstruction (left); Reconstruction (right) Surgery 1/29/2015 Lumpectomy: Right Dx 2/2/2015, IDC, Right, 1cm, Grade 2, 0/0 nodes, ER+/PR-, HER2- (FISH) Dx 2/25/2015, IDC, Right, 1cm, Grade 3, 0/13 nodes, ER+/PR-, HER2- (IHC) Surgery 2/25/2015 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary; Prophylactic ovary removal Chemotherapy 3/31/2015 AC + T (Taxol) Radiation Therapy 8/25/2015 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy Femara (letrozole)
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Mar 14, 2019 07:28PM Barteeellis wrote:

I cannot find anything online that says inflammation could possible cause elevated Ca 15-3. Where would I find info on it? Thank you so much for your reply

Dx 7/7/2007, IDC, Right, 2cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2-
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Mar 14, 2019 08:05PM KBeee wrote:

There probably are sites, but I do not know off hand. My MO always says he does not do tumor markers because a variety of inflammation/inflammatory conditions can cause it to rise. I think things like cirrhosis, hepatitis, endometriosis, PID are some, but there are others.


Hoping yours is for some benign reason. Hoping you get answers!

Karen. Dx 8/5/2013, IDC, Right, 1cm, Grade 2, 0/1 nodes, ER+/PR+, HER2- (IHC) Surgery 8/26/2013 Mastectomy: Left, Right Chemotherapy 9/20/2013 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 12/12/2013 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 1/23/2014 Reconstruction (left); Reconstruction (right) Surgery 1/29/2015 Lumpectomy: Right Dx 2/2/2015, IDC, Right, 1cm, Grade 2, 0/0 nodes, ER+/PR-, HER2- (FISH) Dx 2/25/2015, IDC, Right, 1cm, Grade 3, 0/13 nodes, ER+/PR-, HER2- (IHC) Surgery 2/25/2015 Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary; Prophylactic ovary removal Chemotherapy 3/31/2015 AC + T (Taxol) Radiation Therapy 8/25/2015 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy Femara (letrozole)
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Mar 15, 2019 11:16AM muska wrote:

I ran across an interesting write up about tumor markers, here's the link. However, it does not address the OP's question.

Dx at 54 Dx 5/9/2013, DCIS/IDC, Right, <1cm, Stage IIIA, Grade 3, 7/11 nodes, ER+/PR+, HER2- (FISH) Surgery 6/12/2013 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Dx 6/13/2013, LCIS, Both breasts Chemotherapy 7/24/2013 AC + T (Taxol) Surgery 2/19/2014 Reconstruction (left); Reconstruction (right) Hormonal Therapy 3/11/2014 Arimidex (anastrozole) Radiation Therapy 3/22/2014 Breast, Lymph nodes, Bone
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Mar 15, 2019 08:53PM bevin wrote:

I'd personally get another blood test in a month, if still elevated, get the scans. better to be certain. Good luck, sorry you have to make this decision, but good you have the options available

Age 45, Oncotype 11, Primary Tumor 2.1 cm, smaller satellite tumor nearby Dx 8/8/2010, IDC, 2cm, Stage II, Grade 3, 0/5 nodes, ER+/PR+, HER2- Surgery 8/10/2010 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 10/10/2010 Breast
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Mar 16, 2019 01:05PM - edited Mar 16, 2019 01:05PM by trinigirl50

My tumour markers elevate any time I have bursitis, or if I strain my back, or if I bump my leg, or if I go on a long long walk, or if I overdo the dancing, all of which happens quite often. I do a 'dance marathon' every March and usually my tumour markers are elevated. By June they drop back down to normal. I did have a scan the first time they jumped up (to 43), bone scan, CT scan the works. Eventually they dropped back down to 29 (30 is the limit at my lab). Same with my CEA results, been all the way to 9, then down to 1 - mainly they are around 3. So although you can't find much info about inflammation and tumour markers, I am living proof that they are affected. Maybe you are just getting more arthritic? Here's hoping for clear scans on Wednesday.

trinigirl50 Dx 3/7/2015, ILC, Left, 6cm+, Stage IIIC, Grade 2, 20/24 nodes, ER+/PR-, HER2- Surgery 3/7/2015 Lymph node removal: Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Chemotherapy 4/13/2015 AC + T (Taxotere) Hormonal Therapy 9/14/2015 Arimidex (anastrozole), Femara (letrozole) Radiation Therapy 10/1/2015 Whole-breast: Breast, Lymph nodes
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Mar 16, 2019 01:51PM Barteeellis wrote:

thank you so much for your post. It give me hope that that is what is going on with me. I have been 11 years out and this is something you always fear. I will be glad to get all the tests and scans over with.

Dx 7/7/2007, IDC, Right, 2cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2-
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Mar 18, 2019 02:41PM Barteeellis wrote:

trinigirl50 I just had terrible osteorarthritis in my mid foot, I really needed surgery but got a cortisone shot in the foot 2 days before my Blood work for the CA 15-3. Also I had influenza which was confirmed with the flu test about a week prior to the blood work. I am 61, so yes I have arthritis and even have had bursitis in my hip but advil helps there. I am having all the scans on Wednesday but I don't see the doc until the next wednesday for results. I asked my ONC about the foot issue but he did not think it would cause the elevation of the Ca 15-3. You are right about not finding much online about inflammation causing elevations. I want to be hopeful since I'm 11 years out of my treatments etc. I am almost paralyzed with fear right now and can think of nothing else.


Dx 7/7/2007, IDC, Right, 2cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2-
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Mar 18, 2019 04:46PM Mamasha wrote:

hello barteeellis,

My sister was just given the same news that her numbers were up she’s waiting for them to call with scanappointment. I feel terrible that you are going through this waiting game. So stressful which isn’t good

Hugs and positive thoughts your way

Dx 12/2016, IDC, Right, <1cm, 0/3 nodes, ER+/PR+, HER2- Surgery 1/4/2017 Lumpectomy: Right Radiation Therapy 2/6/2017
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Mar 18, 2019 05:21PM trinigirl50 wrote:

Barteeellis

I can empathise. I still spend at least three months of the year petrified about mets. Good luck with your scans.

trinigirl50 Dx 3/7/2015, ILC, Left, 6cm+, Stage IIIC, Grade 2, 20/24 nodes, ER+/PR-, HER2- Surgery 3/7/2015 Lymph node removal: Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Chemotherapy 4/13/2015 AC + T (Taxotere) Hormonal Therapy 9/14/2015 Arimidex (anastrozole), Femara (letrozole) Radiation Therapy 10/1/2015 Whole-breast: Breast, Lymph nodes
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Mar 21, 2019 09:41AM trinigirl50 wrote:

Hi Barteellis

I hope all went well yesterday.


trinigirl50 Dx 3/7/2015, ILC, Left, 6cm+, Stage IIIC, Grade 2, 20/24 nodes, ER+/PR-, HER2- Surgery 3/7/2015 Lymph node removal: Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Chemotherapy 4/13/2015 AC + T (Taxotere) Hormonal Therapy 9/14/2015 Arimidex (anastrozole), Femara (letrozole) Radiation Therapy 10/1/2015 Whole-breast: Breast, Lymph nodes
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Mar 21, 2019 01:54PM Barteeellis wrote:

I got through all the testing. Of course the technicians cannot tell you anything so now I wait until next Wednesday for results. The testing was not uncomfortable and it went fast. Thank you for checking in

Dx 7/7/2007, IDC, Right, 2cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2-
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Mar 21, 2019 03:00PM trinigirl50 wrote:

Good. I hope all scans are clear. Keep us posted. Now plan something that will keep you distracted for the weekend.

trinigirl50 Dx 3/7/2015, ILC, Left, 6cm+, Stage IIIC, Grade 2, 20/24 nodes, ER+/PR-, HER2- Surgery 3/7/2015 Lymph node removal: Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Chemotherapy 4/13/2015 AC + T (Taxotere) Hormonal Therapy 9/14/2015 Arimidex (anastrozole), Femara (letrozole) Radiation Therapy 10/1/2015 Whole-breast: Breast, Lymph nodes
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Apr 4, 2019 07:54PM trinigirl50 wrote:

Hi Barteeellis

Hope all is well.



trinigirl50 Dx 3/7/2015, ILC, Left, 6cm+, Stage IIIC, Grade 2, 20/24 nodes, ER+/PR-, HER2- Surgery 3/7/2015 Lymph node removal: Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Chemotherapy 4/13/2015 AC + T (Taxotere) Hormonal Therapy 9/14/2015 Arimidex (anastrozole), Femara (letrozole) Radiation Therapy 10/1/2015 Whole-breast: Breast, Lymph nodes
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Apr 5, 2019 09:41AM Barteeellis wrote:

Thanks for checking in..The scans on bone are negative. On the CT they saw some very small nodules which the radiologist said were most likely intrapulmonary lymph nodes and I will need to be rescanned in 3 months to make sure. My MO says they are most likely nothing but we will check them out to be sure. Everything else showed nothing. What I have been able to see and been told they are from irritants or illness, which I had just had the flu. I have to get my CA 15-3 rechecked the end of May. I hate all this waiting!!! The anxiety is over the moon! I cannot find much online about false positive tumor markers. So I wait

Dx 7/7/2007, IDC, Right, 2cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2-
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Apr 6, 2019 01:45PM trinigirl50 wrote:

Thats great that they think all is well. Waiting is hard I know. I promise you that inflammation, illness (flu) affect the markers. That is why many Drs are often reluctanct to use them. Breathe, this too shall.pass.

trinigirl50 Dx 3/7/2015, ILC, Left, 6cm+, Stage IIIC, Grade 2, 20/24 nodes, ER+/PR-, HER2- Surgery 3/7/2015 Lymph node removal: Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right Chemotherapy 4/13/2015 AC + T (Taxotere) Hormonal Therapy 9/14/2015 Arimidex (anastrozole), Femara (letrozole) Radiation Therapy 10/1/2015 Whole-breast: Breast, Lymph nodes

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