Join Us

We are 225,032 members in 83 forums discussing 163,852 topics.

Help with Abbreviations

Topic: IDC premenopausal positive node Oncotype score questioning chem?

Forum: "Middle Age" 40-60(ish) Years Old With Breast Cancer —

Meet others in this age-range who share similar life issues.

Posted on: Jul 17, 2015 06:42AM

4pink101 wrote:

I am 43 have IDC.. Had BMX positive sentinel node ALND 6 all negative. Oncotype score 18 indicating no decrease in recurrence with chemo .. Not sure how to proceed given its been suggested by the MO as the standard of care. Anyone out there in a similar situation

Dx 2/2015, IDC, Left, 2cm, Stage IIA, Grade 2, 1/7 nodes, ER+/PR+, HER2- Surgery Lymph node removal: Sentinel, Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant
Log in to post a reply

Page 1 of 1 (12 results)

Posts 1 - 12 (12 total)

Log in to post a reply

Jul 17, 2015 11:02AM Colleen73 wrote:

4pink101- Curious as to what stage cancer you have?

My Oncotype is 21 and I chose Radiation and Tamoxifen due to Stage 1 grade 2

Dx 4/22/2015, IDC, Left, 1cm, Stage IB, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Surgery 5/7/2015 Lumpectomy; Lymph node removal: Sentinel Radiation Therapy Breast, Chest wall Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
Log in to post a reply

Jul 18, 2015 02:46PM 4pink101 wrote:

colleen73-I am stage 2B.. 2.1cm tumor with macro met in sentinel node.. Addt 6 nodes negative. I already had a BMX and am trying to determine which treatment going forward is best??

Dx 2/2015, IDC, Left, 2cm, Stage IIA, Grade 2, 1/7 nodes, ER+/PR+, HER2- Surgery Lymph node removal: Sentinel, Underarm/Axillary; Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant
Log in to post a reply

Jul 18, 2015 04:47PM ksusan wrote:

I wasn't oncotyped because my surgeon and MO said that if you're node+, the recommendation is for chemo.

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
Log in to post a reply

Jul 18, 2015 06:04PM labelle wrote:

You've written "Oncotype score 18 indicating no decrease in recurrence with chemo" If this is correct, why would you want to or be offered chemo? For what reason are any of your doctors saying you should have chemo if they are saying it will not decrease your risk of recurrence? I'd ask them why they think you need it if they don't believe it will decrease your risk of recurrence. Might it benefit you in some other way? If not, then why do it? Just because it is the "standard of care" isn't a good enough reason IMO.

Dx 9/29/2014, IDC: Tubular, Left, <1cm, Stage IIA, Grade 1, 1/11 nodes, ER+/PR+, HER2- (FISH) Surgery 11/13/2014 Lumpectomy: Left; Lymph node removal: Sentinel Radiation Therapy Whole-breast: Breast
Log in to post a reply

Jul 23, 2015 01:52AM Cmo65 wrote:

My onco score was also 18. Because I was Stage 1, grade 1, my dr did not recommend chemo. Just rads and tamoxifen. The chemo only provide a 1% benefit to me

Dx 3/9/2015, IDC, <1cm, Grade 1, ER+/PR+, HER2- Surgery 3/16/2015 Lumpectomy: Right Surgery 3/16/2015 Lymph node removal: Right, Sentinel Radiation Therapy 5/11/2015 Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
Log in to post a reply

Dec 11, 2015 06:14PM alf9511 wrote:

I am 45 and was diagnosed in September of this year and also had er/pr positive tumor, 2.4 cm., small trace of cells in sentinel node and no trace in the other 4 nodes.  I had a BMX too.  My oncotype score is 17 and I am deciding whether or not to have chemo.  What did you ultimately decide to do?

Dx 9/22/2015, DCIS/IDC, Right, 2cm, Stage IIB, Grade 1, 1/5 nodes, ER+/PR+, HER2-
Log in to post a reply

Dec 11, 2015 06:55PM labelle wrote:

This now seems to be a gray area. Not too long ago if you had a positive node, chemo was pretty much a given. Only in recent years are some doctors saying even with a node or two positive, if the oncotype is low, no chemo.

Both my doctors (at Vanderbilt and UT) told me no chemo with an oncotype of 11-even though I had a positive node. In my case, both my first and second opinion doctors agreed it would not help me. You might want a second opinion, as the suggested treatment seems to be swinging toward no chemo in our situations (low oncotype/one or two positive nodes).

Dx 9/29/2014, IDC: Tubular, Left, <1cm, Stage IIA, Grade 1, 1/11 nodes, ER+/PR+, HER2- (FISH) Surgery 11/13/2014 Lumpectomy: Left; Lymph node removal: Sentinel Radiation Therapy Whole-breast: Breast
Log in to post a reply

Dec 11, 2015 09:53PM alf9511 wrote:

thanks

Dx 9/22/2015, DCIS/IDC, Right, 2cm, Stage IIB, Grade 1, 1/5 nodes, ER+/PR+, HER2-
Log in to post a reply

Mar 1, 2016 07:15PM ThinkingPositive wrote:

does anyone know what exactly determines whether your oncotype results are going to be high or low? Is it the grade of the cancer that pushes the number up or is that the fact that you have nodes that are positive . I didn't have the test my am oh you said it would probably come back.

Dx 9/2014, DCIS/IDC, Left, 1cm, Stage IIA, Grade 3, 1/17 nodes, ER+/PR+, HER2- Surgery 10/22/2014 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left; Reconstruction (left): Silicone implant, Tissue expander placement; Reconstruction (right): Silicone implant Chemotherapy 12/4/2014 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy Femara (letrozole)
Log in to post a reply

Mar 4, 2016 12:27PM - edited Mar 4, 2016 12:28PM by etnasgrl

The Oncotype test is done on women who:

1) Have Stage 1 or Stage 2 invasive breast cancer.
2) Have estrogen-receptor-positive
3) No cancer in the lymph nodes (Women who have cancer in the lymph nodes do not get the Oncotype Test.)

Your score is based on the 21 genes of your own personal tumor that can influence how likely the cancer is to grow and respond to treatment.
I had Invasive Ductal Carcinoma, Stage 1, Grade 2, clean margins and no cancer in the lymph nodes.
My Oncotype score was 27 which is in the intermediate range.
I decided NOT to do chemo. I had a lumpectomy, followed by radiation, and am now on Tamoxifen for 10 years.

Diagnosed at 41. Diagnosed 2nd time at 45. Dx 11/5/2015, IDC, Right, 1cm, Stage IA, Grade 2, 0/1 nodes, ER+/PR+, HER2- Surgery 12/9/2015 Lumpectomy: Right; Lymph node removal: Sentinel Radiation Therapy 1/11/2016 Whole-breast: Breast Hormonal Therapy 2/17/2016 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 2/13/2020, IDC, Left, <1cm, Stage IA, Grade 3, 0/3 nodes, ER-/PR-, HER2+ (IHC) Surgery 2/23/2020 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 3/18/2020 Taxol (paclitaxel) Targeted Therapy 3/18/2020 Herceptin (trastuzumab) Surgery 8/19/2020 Mastectomy: Left, Right; Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap
Log in to post a reply

Mar 4, 2016 09:01PM Hopeful82014 wrote:

Sorry, Etnasgirl, but node + women DO have their tissue Oncotyped. The test has been validated for ER+ tumors with 1-3 positive nodes.

The test hasn't been used for node + for as long as node negative but both the MOs I consulted felt it was valid. One is at a major research institute, the other heads the breast cancer research arm of her (large) institution.

Based on the predicted minimal additional benefit, I did not have chemo.
Dx IDC
Log in to post a reply

Mar 4, 2016 11:49PM Optimist52 wrote:

I had micromets in two nodes and was offered the test. My result was 22 and MO said on balance better to get on with hormone therapy as soon as possible.

Second diagnosis PILC - Oncotype 22, isolated tumour cells in 2 nodes Dx 10/2003, ILC, Left, 1cm, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 10/22/2003 Lumpectomy: Left; Lymph node removal: Sentinel Radiation Therapy 1/2/2004 3DCRT: Breast Hormonal Therapy 3/2/2004 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Dx 6/23/2015, ILC, Left, 4cm, Stage IIA, Grade 2, 0/9 nodes, ER+/PR+, HER2- Surgery 7/5/2015 Lymph node removal: Underarm/Axillary; Mastectomy: Left Hormonal Therapy 8/12/2015 Femara (letrozole)

Page 1 of 1 (12 results)