Sep 8, 2017 01:50PM HeartdesiresLife wrote:
Hello...I wonder if anyone can comment on how accurately small microinvasion can be tested for HER2 status? I had bilateral mastectomy with sentinel node biopsy on 8/25/17 and DCIS 7.1cm on the left with 0.7mm microinvasion and during the estrogen testing, it seems the sample basically just disappeared according to the medical oncologist who spoke to the pathologist. Pathologist was also unable to definitively say whether it was the microinvasion which tested positive for HER2 (FISH) and not the DCIS as the sample they took may have gotten some DCIS as well. I guess one way to help figure this out would be to test DCIS itself and if HER2-, then it would be the microinvasion which tested HER2+. Of course if DCIS is HER2+, then back to square one.
I will probably end up requesting a second look at the pathology along with a 2nd medical oncology advice but I was wondering about anyone's input about testing for something so small.
Also in regards to Taxol/Herceptin, anyone receiving or have received modified/less than the standard regime of 3 months combined and 9 months of Herceptin? I tend to be hypersensitive to medication's effects, so I wonder even if I decide to go this route whether I will be able to tolerate it.
Thank you very much!