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Topic: Delayed herceptin after receiving chemo and radio

Forum: DCIS plus HER2-positive Microinvasion —

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Posted on: May 22, 2018 08:05AM

Zahid wrote:

Please help me. I am in deep trouble. My mother had mastectomy done then the oncologist gave 8 cycles of chemo therapy then 15 radio therapy and after that they suggested for herceptin injection. Now I am in India and the indian doctors are suggesting that herceptin should be given with chemo and now your mother has finished chemo and radio. Now it is too late and herceptin would not work. What should I do now? Is it true that herceptin would not work now?

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May 22, 2018 08:07AM DATNY wrote:

I am not a health care provider, but I would say the Herceptin will work regardless. Else, they should provide you evidence showing it doesn't work.

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May 22, 2018 08:12AM Zahid wrote:

thanks a lot...I became restless and can not sleep due to anxiety...I was so worried and still crying....I thought that I got lost after coming so close to make my mother cancer free.....

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May 22, 2018 10:24PM - edited May 22, 2018 10:25PM by Icietla

Peace, Zahid.

Yes, administering Herceptin alone following prior Chemotherapy is one of the customary ways to do Herceptin treatment. Read here at the Herceptin information website. Scroll down to the "Indications" section.

My latest (Stage IVB) diagnosis is almost certainly of another distant primary type. To the best of my information and belief, I am still apparently what we call NED as to breast cancer, doubtless thanks to Letrozole. Dx 2/12/2016, ILC, Right, Stage IIA, Grade 1, 0/13 nodes, ER+/PR+, HER2- Surgery 2/19/2016 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Right; Prophylactic mastectomy: Left Hormonal Therapy 4/1/2016 Femara (letrozole) Surgery 4/25/2016 Prophylactic ovary removal Dx 8/2018, Stage IV
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Jun 10, 2018 10:25AM gsonet wrote:

I presented with a large tumor. The initial biopsy said it was Estrogen and Progesterone + but HER2-.

I had ACT and 12 rounds of Taxol. My tumor shrank, but not drastically. After surgery, a biopsy was done, now, with a lot of tissue. It showed that I was HER2+. My oncologist thinks the most likely explanation is that I had a heterogenous tumor - some cells were HER2+ and some were not. Unfortunately, the original biopsy missed the + cells. I repeated the 12 taxols, adding in Herceptin every third week. He said it is more effective when given with Taxol. I don't think it's ever too late to get Herceptin. Obviously, it's better to get it sooner than later!

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Jun 10, 2018 01:21PM Moderators wrote:

Dear gsonet,

Welcome to the BCO community and thank you for sharing your story. We are sure that it will be helpful to other members. Please stay active here and let us know if there is any help you need with navigating the boards. The Mods

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