Topic: Chek2 with no cancer and DMX?

Forum: Genetic Testing — ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, NBN, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53, and mismatch repair genes (MLH1, MSH2, MSH6, PMS2, EPCAM)

Posted on: May 2, 2022 12:00AM

Posted on: May 2, 2022 12:00AM

joemama wrote:

Has anyone found they have chek2, no positive tests for cancer, and went straight to DMX?

I’m considering looking into this option but was wondering how common it is to do this route.

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May 2, 2022 04:00PM monarchandthemilkweed wrote:

i have chek2. Knew about it for a few years. Was getting mammograms/ ultrasounds amen MRI’s. MRI picked up a tiny 6 mm tumor. Had the DMX.

Have you spoken to a genetic counselor? Chek2 is a moderate risk gene. Typically a preventative dmx is not indicated. Do you have a strong family history of breast cancer ? Or other cancers? Chek2 raises the risk of colon cancer. What variant do you have of chek2? Some are worse than others.

Sorry you also have the chek2 gene. It’s no fun

Dx 3/11/2021, IDC, Left, <1, Stage IA, Grade 2, ER+/PR+, HER2- Hormonal Therapy 3/11/2021 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 10/5/2021 Mastectomy (Left): Skin Sparing; Mastectomy (Right): Skin Sparing; Prophylactic mastectomy (Right); Reconstruction (Left); Reconstruction (Right): Tissue Expander Surgery 6/15/2022 Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)

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