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Topic: Prolia injection and immediate side effects

Forum: Bone Health and Bone Loss —

Talk with others about bone density, osteopenia and osteoporosis, and ways to keep your bones strong

Posted on: Feb 21, 2020 11:25AM

Cubbie2015 wrote:

I've been taking Arimidex in conjunction with ovarian suppression, and my last bone density scan shows my osteopenia has gotten somewhat worse. My hips are the same, but I've lost some more density in my lower back. My bone density didn't start from a good place when I began treatment, as it turned out that I was very deficient in Vitamin D and didn't know it. I now take 5000 IU Vitamin D each day, and my levels are normal. My doctor would like to start me on Prolia next month to try to combat the bone loss.

I'm aware of the long term side effects of Prolia, but I'm wondering what the immediate side effects are following the shot. I've heard that some people feel like they have the flu the following day. Right now I'm scheduled to have my first shot on a Wednesday, and I'm wondering if I'm going to feel up to going into work on Thursday. For those of you who have taken Prolia, how did you feel in the days following your shot?

1.8mm micromet in sentinel node; BRCA negative; chose bmx due to family history; age 43 at diagnosis; Oncotype 15 Dx 9/4/2015, IDC, Left, 1cm, Stage IIA, Grade 1, 1/2 nodes, ER+/PR+, HER2- (FISH) Surgery 10/8/2015 Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy 12/16/2015 Whole-breast: Lymph nodes, Chest wall Hormonal Therapy 1/12/2016 Zoladex (goserelin) Hormonal Therapy 6/28/2016 Arimidex (anastrozole)
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Feb 21, 2020 11:37AM ctmbsikia wrote:

Hi there. I had my 1st shot in December and I am happy to report that it was uneventful and the easiest thing I've done to date!!! I felt no different, and I hope you do too!

Dx 12/14/2017, DCIS/IDC, Left, 4cm, Stage IIB, Grade 2, 1/2 nodes, ER+/PR+, HER2- Dx 1/16/2018, LCIS, Right Surgery 1/30/2018 Lumpectomy: Left; Lymph node removal: Sentinel Radiation Therapy 4/10/2018 Whole-breast: Breast Hormonal Therapy 6/25/2018 Arimidex (anastrozole)
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Feb 21, 2020 12:41PM Spookiesmom wrote:

My DH has bone Mets, gets the shots with no ill effects.

Reoccurrence 3-19. Dx IDC, Stage IIIA, Grade 3
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Feb 21, 2020 12:57PM edj3 wrote:

I had my first injection last September, and like you I was concerned about how my body would do that day and the next day. My body doesn't always play nicely with medication.

In this case, I needn't have worried--zero issues, not even sore at the injection site that night.

Tried the tamoxifen, no thanks. Dx 4/9/2019, IDC, Left, <1cm, Stage IA, Grade 2, 0/1 nodes, ER+/PR+, HER2- (IHC) Surgery 5/5/2019 Lumpectomy; Lymph node removal: Sentinel Dx 5/6/2019, LCIS, Left, <1cm, 0/1 nodes Radiation Therapy 6/2/2019 Whole-breast: Breast Hormonal Therapy 9/22/2019 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Feb 21, 2020 01:38PM muska wrote:

I had my 8th Prolia injection a month ago. I have never had any immediate or delayed side effects from these shots.

Dx at 54 Dx 5/9/2013, DCIS/IDC, Right, <1cm, Stage IIIA, Grade 3, 7/11 nodes, ER+/PR+, HER2- (FISH) Dx 6/13/2013, LCIS, Both breasts Surgery 6/13/2013 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 7/25/2013 AC + T (Taxol) Surgery 2/20/2014 Reconstruction (left); Reconstruction (right) Hormonal Therapy 3/12/2014 Arimidex (anastrozole) Radiation Therapy 3/23/2014 Breast, Lymph nodes, Bone
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Mar 31, 2020 10:47PM DebbieNinja wrote:

I am the odd one here. I had my 4th Prolia injection in January. I have felt flu like symptoms after each injection so far. The symptoms only last a day or two and aren't terrible. After that I have no side effects at all and feel completely normal until time for my next injection.

DebbieNinja...cancer warrier Dx 8/17/2012, ILC, 2cm, Stage IIB, Grade 3, 1/3 nodes, ER+/PR+, HER2- Surgery 9/6/2012 Mastectomy: Left, Right Surgery 9/6/2012 Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 10/4/2012 AC Chemotherapy 12/5/2012 Taxol (paclitaxel) Hormonal Therapy 2/21/2013 Hormonal Therapy 10/9/2013 Aromasin (exemestane) Surgery 10/9/2013 Prophylactic ovary removal Surgery 12/10/2014 Reconstruction (left); Reconstruction (right) Surgery Reconstruction (right): Silicone implant Surgery Reconstruction (left); Reconstruction (right): Silicone implant

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