Topic: Zometa - side effect and pain

Forum: Bone Health and Bone Loss — Talk with others about bone density, osteopenia and osteoporosis, and ways to keep your bones strong

Posted on: Sep 22, 2022 12:31AM

Posted on: Sep 22, 2022 12:31AM

seveniechewy wrote:

hi all,

My mom was diagnosed stage IIA HER2+ breast cancer last year and has undergone mastectomy, chemo and just completed targeted with herceptin and perjeta.

She also has a history of osteoporosis so we were told by our oncology MO that we could try zometa which supposingly can help osteoporosis with the extra benefit of preventing bone nets and better survival.


she had her first zometa infusion last thurs, over 15 mins. I only just realise that I should’ve told her to stay more hydrated. She had some flu like symptoms with fever and some aches over her body for 2-3 days which was manageable.

However since 2 days ago (around 4 days after her zometa infusion) she started having rather intense pain over her right leg/ calf and some mild pain over her left thigh too. She needs to take regular paracetamol and ibuprofen for the pain and sometimes it disturbs her sleep.

I know that zometa can cause muscle ache and bone pain; but Is this sort of localised pain common after zometa infusion? How long does it usually last? Her last PET was done in august this year and it was clear with no bone mets. It just hurts me to see how the she needs to take regular pills for the pain


thank you all

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Sep 22, 2022 08:16PM parakeetsrule wrote:

She needs to talk to her doctor about this. It doesn't matter if it's common or not. Lots of bad things are common. If the pain is so bad it's disturbing her sleep she needs medical attention!
Stage 2 at 37, Stage 4 at 41. Cancer is dumb. Cookies are good. Dx 3/21/2017, IDC, Left, Grade 2, ER+/PR-, HER2- Radiation Therapy 11/6/2017 Whole breast: Lymph nodes, Chest wall Hormonal Therapy 12/8/2021 Faslodex (fulvestrant) Targeted Therapy 12/13/2021 Piqray (alpelisib) Dx IDC, Other, Stage IV, ER+, HER2- Chemotherapy AC + T (Taxol) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal (Left); Mastectomy (Left)

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