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Jan 20, 2012 04:42AM
I'm curious about that too, but I'm quite sure side effects from supplements could never be as hardcore as those on Tamoxifen. This is my personal opinion of course, but even if one doesn't suffer from Tamoxifen SE's, I would be very worried about the 'silent', unwanted effects.
Concerning the paper I read about iodine levels & eating cruciferous vegs, I knew I read one, but can't seem to find the 'one'. Here's a link from a guide for vegans, where it is stated:
"Iodine is used by the thyroid to maintain a healthy metabolism. "Goitrogens" present in some vegetable and grains, like soy, flax seeds, and raw cruciferous vegetables (broccoli, brussels sprouts, cauliflower, and cabbage) counteract iodine and can cause an enlarged thyroid gland, called a goiter. For this reason, large amounts of soy combined with inadequate iodine intake can make iodine deficiency worse. North American vegans should take a modest iodine supplement but should be careful to not have too much."
I was thinking; if we take supplements like I3C, there is a risk for problems stated above, but if one ups iodine ( a little bit), we should be ok. It makes sense, right? Papers arguing that too much cruciferous vegs are bad, are IMHO telling 'half-truths'.
The following link sums it up quite well concerning cruciferous vegs and studyresults (who are as of yet not 100% consistent- maybe that's why I3C etc have a hard time being taken seriously by oncs, or other people for that matter), and how 'too much' of a good thing (i.e cruciferous vegs) can actually be bad. Then again, I don't think eating vegs can hurt you (My brother-in-law has two FULL plates of steamed broccoli every evening, I'll ask him about his thyroid!). But of course you have to know what you're doing, so you don't end up with hypothyroidism: Eating large amounts of cruciferous vegs & taking supplements are great so as to hinder non desirable estrogen in your body is great, but not if you do your body harm elsewhere. It is oddly hard to achieve balance these days..
About alcohol, it's a shame red wine and its grapes, which contains resveratrol, are loaded with pesticides. Even the organic choices are not 100% yukfree. My onc explained that alcohol raises levels circulating estrogen to the roof in younger women, and not only does it congest your liver, but also interferes with its metabolism. This makes sense, as drinkers tend to have 'beerbellys' (bellyfat full of harmful estrogen). I found a link to a study discussing the benefits of drinking when postmenopausal, quite interesting. It also says "Alcohol could enhance estrogenic effects by increasing the circulating levels of the hormone or by increasing the number of estrogen receptors in bone cells", which supports the sayings of my onc.
Another link to a surgeons blog, she is dicussing results of a study which appeared in Journal of Clinical Oncology;
Mandalala, define 'doing nothing' :-) In my mind, I guess oncs are worried that patients are not looking for ways to build better health and avoid recurrence post BC treatments, which is so important for every cancer, and also hormonedependent BC (which we are discussing here). They maybe prefer putting us on Tamoxifen, as they are not sure we will take responsibility for our own health, and of course as studies about for example cruciferous vegs are still inconclusive, rather than suggesting alternative ways, although every cancer is different. I mean that if I choose to take care of myself in a certain way, founded on what I think caused my cancer, will not be 100% applicable to my neighbor, nor physically nor mentally, as we all come from different lives and backgrounds. Maybe oncs don't have the time, energy or interest to do case by case consultations (which they should of of course).