We are 224,331 members in 82 forums discussing 157,699 topics.

Help with Abbreviations

Topic: Pathology test showed ILC & E-Cadherin showed IDC

Forum: Mixed Type Breast Cancer — Meet others who have mixed type breast cancer.

Posted on: Jul 31, 2017 02:53AM

LCY wrote:

HI. I am new to the group and I am still learning about breast cancer. I have undergone total mastectomy with sentinel lymph node dissection last June 28, My cancer was Stage 1A, nuclear grade 1. Prior to surgery, a core needle biopsy was done which came back with the results of Invasive Lobular Cancer (ILC). The Pathology report done after the mastectomy correlated the same findings - ILC, but suggested that E-Cadherin test be done. The E-Cadherin test results came back with Invasive Ductal Carcinoma. The tumor is only 1.1 cm and is ER+, PR+, HER2-.

Initially, I was told that I might not need to undergo chemotherapy anymore due to the low stage. None of the lymph nodes tested/removed indicated cancer. However, due to the results of the E-Cadherin test, I am now told that there is still the possibility of undergoing chemo.

What does this mean? And what is the difference in treating ILC, IDC, or mixed type cancer?

Log in to post a reply

Page 1 of 1 (4 results)

Posts 1 - 4 (4 total)

Log in to post a reply

Jul 31, 2017 02:00PM kira1234 wrote:

I'm not sure why being IDC rather than ILC would change chemo for stage 1. I'd request the oncotype test or the mammaprint test be done

Dx 6/2010, ILC, Left, <1cm, Stage IA, Grade 1, 0/1 nodes, ER+/PR+, HER2- Surgery 7/7/2010 Lumpectomy: Left; Lymph node removal: Left, Right, Sentinel Radiation Therapy 8/2/2010 Hormonal Therapy 10/4/2010 Aromasin (exemestane) Dx 2/2017, ILC, Left, <1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR-, HER2- Hormonal Therapy Arimidex (anastrozole) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right
Log in to post a reply

Jul 31, 2017 03:19PM Mucki1991 wrote:

Hi, I too have mixed mine is, Invasive high-grade mammary carcinoma with mixed ductal, lobular and micropapillary features, node-positive. I'm not sure either why it would change whether or not you would chemo. I am curious as to how common mixed cancers are? I am meeting with my onc for the first time next week and I eager to find out his views on this. I had my BMX on the 14th so I'm really just getting to the treatment stage now.

Rebekah Dx 5/5/2017, ILC/IDC/IDC: Papillary, Left, 3cm, Stage IIB, Grade 3, 3/7 nodes, ER+/PR+, HER2- (IHC) Surgery 7/13/2017 Mastectomy: Left; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 8/22/2017 AC + T (Taxol) Surgery 2/8/2018 Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Radiation Therapy 2/25/2018 3DCRT: Breast, Lymph nodes, Chest wall Hormonal Therapy 4/19/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery 9/17/2018 Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap Surgery 1/24/2019
Log in to post a reply

Jul 31, 2017 05:20PM letsgogolf wrote:

I think it is fairly common to have mixed tumors.. Mine was IDC with Lobular features, grade 1. I have been told that 50% of this type of tumor involve 1 node only and that they are less likely to cause mets. They also have a higher rate of second primary tumors.

Oncotype DX = 3. IDC with Lobular Features. Sentinel Node had Micrometastases - Estrogen 100%, Progesterone 99.89%, Ki67= 3.3% Dx 2/14/2017, IDC, Left, 1cm, Stage IB, Grade 1, 0/8 nodes, ER+/PR+, HER2- Surgery 2/26/2017 Lumpectomy: Left Radiation Therapy 4/5/2017 Whole-breast: Lymph nodes Hormonal Therapy 5/31/2017 Arimidex (anastrozole) Targeted Therapy
Log in to post a reply

Nov 16, 2017 08:19PM beach2beach wrote:

Not sure LCY if you are on here any longer, but I was initially diagnosed on biopsy as IDC. After surgery, pathology came back as ILC so they had to check the nodes with a different type of stain to make sure it had not spread. My pathology also came back as well with DCIS and LCIS as well. All in a 7mm tumor.

Dx 7/28/2017, LCIS/DCIS/ILC, Right, <1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Surgery 8/8/2017 Mastectomy: Left, Right; Reconstruction (left); Reconstruction (right) Hormonal Therapy 9/11/2017 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)

Page 1 of 1 (4 results)