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Topic: Mucinous Carcinoma of the breast

Forum: Less Common Types of Breast Cancer — Meet others with less common forms of breast cancer, such as Medullary carcinoma, Inflammatory breast cancers, Mucinous carcinoma (colloid carcinoma), Paget's disease, Papillary carcinoma, Phyllodes tumor, Tubular carcinomas, Metaplastic tumors, Adenoid cystic carcinomas and Angiosarcoma.

Posted on: Apr 23, 2009 07:43PM

peggym wrote:

On April 21st I had a core biopsy and today I was told that I have mucinous carcinoma of the breast.  When I investigated on this website, the information given was that this is a rare type of cancer, about 2-3% of all breast cancers and usually occurs in post-menopausal women over the age of 60.  I am neither.  I am 51 years old, but still menstruate.  I have an appointment with a surgeon, but feel as though I am in the state of shock.  This "nodule" was found on routine mammogram and I convinced myself that it was nothing.

This may sound odd at my age, but I just recently started to enjoy and like 'these babies'.  The thought of losing my breast scares me tremendously, and I have not even considered the thought of this cancer metastasizing.  I won't think of that!

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Aug 8, 2019 07:39PM obsolete wrote:

Alderaan and Phg01161, Hello and welcome to our M.C. group. I'm very sorry that you have the need to be here. Please know that you ladies are not alone, even though we are small in number.

Your Invasive Mammary Carcinoma with Mucinous Features is sometimes a diagnosis similar to mixed mucinous, which is most often mixed with a certain % of conventional IDC. Unfortunately, not all Breast Pathologists are trained alike nor do the pathologists get into the nitty gritty with the patient on their tumor's molecular subtype (phenotype Luminal A vs. Luminal B, etc.), which, IMHO, is also important.

As VR stated earlier, surgical & treatment options are a personal decision. You may be interested in reading the following. Best wishes to all who are navigating this complicated rare disease!

Mucinous Breast Cancer Should Not Be Undertreated https://www.medscape.com/viewarticle/714088


Some recent research has suggested that, in cases of mucinous carcinoma,
a certain percentage of women will have more than one mucinous tumor in
the breast. For example, a 2009 study at M.D. Anderson Cancer Center
found that, in a sample of more than 260 women with mucinous carcinoma,
about 38% had more than one area of cancer within the breast. Research
is ongoing, but you may want to discuss this information with your
doctor and see what he or she recommends." https://www.breastcancer.org/symptoms/types/mucinous/treatment

Mucinous Breast Carcinoma: Occult Multifocality/Multicentricity in a Favorable Disease

Purpose: Mucinous carcinoma is a
distinctive tumor that reportedly has a very favorable prognosis.
Accordingly, investigators have recommended that patients be treated
with minimal effective therapy rather than maximum tolerated treatment.
However, previous reports have been limited by small sample sizes and
very short follow-up intervals. We have previously reported outcomes for
a mature data set with long term follow-up and now perform the current
analysis to emphasize comprehensive multidisciplinary management in an
era of minimal effective therapy for so-called favorable disease.Methods and Materials:
We retrospectively reviewed charts for 264 patients with a pure
mucinous carcinoma diagnosis at our institution from 1965-2005.
Multidisciplinary management is emphasized for all patients at our
institution including this patient cohort. All pathology was centrally
reviewed. Overall survival, DM-free survival, and local-regional control
were compared using Kaplan Meier method and log rank statistics.Results:
Median age was 57 years (range 25-89). Median follow-up was 168 months.
86% of patients were stage T2 or less. Patients who were lymph node
negative compared with 1-3 LN+, or 4 or more LN+ were 80%, 15%, and 5%
respectively. 44% received BCT while the remainder underwent mastectomy.
51% of all patients received XRT. No patient in this cohort received
partial breast irradiation. 10% of patients had an initial
multicentric/multifocal presentation. However, a detailed pathology
review revealed a 38% multifocal/multicentric disease rate after
surgical resection. The occult tumors were not initially detected by
mammography or ultrasonography
.5, 10, and 15 year OS, DMFS, and LRC
rates for all patients were: 95%/88%/83%; 97%/95%/92%; and 97%/94%/85%
respectively. There was no statistically significant difference in OS,
DMFS, or LRC based upon surgical management by mastectomy in comparison
with BCT. Likewise, there was no statistically significant improvement
in OS or DMFS with utilization of whole breast XRT. There was, however, a
trend for improved LRC in patients who received XRT (p=0.06) in
comparison with patients who underwent mastectomy or BCT without XRT.Conclusions:
This large series of patients diagnosed with pure mucinous breast
carcinoma demonstrates potentially favorable prognosis. However, this is
the first known report of an association with significant occult
multicentricity/multifocality. In an era of minimal effective cancer
therapy which includes no additional treatment post resection in
favorable histology, and partial breast XRT in favorable histology,
multidisciplinary management inclusive of pathology and diagnostic
imaging is recommended. Current treatment guidelines should reflect that
before omitting whole breast XRT, patients should have pathologic and
radiologic intraoperative correlation and MRI should be a consideration
in efforts to identify potential occult disease.
Citation Information: Cancer Res 2009;69(24 Suppl):Abstract nr 4117.

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Aug 15, 2019 02:45PM Lime wrote:

Thankfully I am 8 years out from surgery but I have always been curious about a characteristic of my tumor that was mentioned in my pathology report. It stated that I had about 15 percent signet ring cells contained within my tumor. Does this have any significance

Dx 7/1/2011, IDC: Mucinous, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ Chemotherapy 9/6/2011 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole) Targeted Therapy Herceptin (trastuzumab) Surgery Mastectomy: Right; Reconstruction (right): Nipple reconstruction, Silicone implant, Tissue expander placement
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Aug 15, 2019 02:53PM - edited Aug 15, 2019 02:54PM by Lime

This Post was deleted by Lime.
Dx 7/1/2011, IDC: Mucinous, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ Chemotherapy 9/6/2011 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole) Targeted Therapy Herceptin (trastuzumab) Surgery Mastectomy: Right; Reconstruction (right): Nipple reconstruction, Silicone implant, Tissue expander placement
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Aug 15, 2019 06:42PM voraciousreader wrote:

lime..congrats on 8 years!


Regarding signet cells...here is a recent study...


https://diagnosticpathology.biomedcentral.com/articles/10.1186/s13000-016-0584-1


And the conclusion...


In summary, our results indicate that instead of SRC population and types, the expression level of MUC1 and/or the presence of cytoplasmic staining with circumferential membranous accentuation pattern in breast cancers showed significant association with adverse clinicopathological parameters. The expression levels of MUC2, MUC4, and MUC5AC had no clinical implication. The utility of MUC1 expression as a prognostic indicator remains to be further assessed using a larger number of cases.



From what I had previously read in older studies, the amount of signet cells seemed prognostic. However, it appears the MUC1 expression seemed more relevant toprognosis. With that said, since you are 8 years post diagnosis, it would seem unlikely that you would have a more aggressive form of the disease.


If you are concerned, perhaps you can ask for your tumor to be evaluated further. At the very least, your tumor can be studied. Perhaps your specimen could be added to the group of cases that have been identified and then followed for prognostic evaluation.

Keep us posted and good luck!

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Aug 15, 2019 06:46PM voraciousreader wrote:

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162088


One more study... looks like PRIMARY signet ring breast caner is more aggressive than when it is found with Mucinous breast cancer...


I must say, until today, I did not know about that variant. Thanks for helping enlighten me

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Aug 28, 2019 11:14AM Auburngal wrote:

Hello All!

It's so refreshing to find this thread as well as the website! I was diagnosed with MC in July of 2017. I completed 8 rounds of chemotherapy (AC and Taxol) and had a bilateral mastectomy in January of 2018 and a preventative hysterectomy in May of 2018. The aggressive treatments were due to my tumor size which was 8cm. Surgeon felt he wouldn't get clear margins unless I completed chemotherapy to shrink the tumors.

Today I am 8 weeks out from a Diep flap procedure which, overall, has gone well. My PS told me to come off of the Femara while my wounds are healing. I have noticed I feel more like "me" again after coming off of the Femara....I have been on it a little over a year and suffered from brain fog, joint pain and stiffness and overall malaise. I assumed my side effects were from chemo, however, I realize it was due to the Femara. I am now questioning if I need the Femara since I had such aggressive treatments for this type of cancer. My oncologist is firm in regards to me staying on the Femara or trying Arimidex instead to see if the side effects are less noticeable. I'm having a difficult time remaining convinced on the hormone therapy as I feel so much better off of it.

Has your treatment plans included AI's? If I don't go back to taking the AI's what are my percentages of cancer returning? I appreciate your insight! Hugs to all!

Dx 7/28/2017, IDC: Mucinous, Left, 6cm+, Stage IIIB, Grade 3, ER+/PR+, HER2- Chemotherapy 8/23/2017 AC + T (Taxol) Surgery 1/5/2018 Lymph node removal: Left; Mastectomy: Left, Right Surgery 5/23/2018 Prophylactic ovary removal Hormonal Therapy 7/5/2018 Femara (letrozole) Surgery 6/24/2019 Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap
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Aug 28, 2019 06:57PM voraciousreader wrote:

auburn...hope you recover soon from your surgery. With respect to being on an AI....first off, due to your staging you didn’t qualify for the OncotypeDX test to determine exactly how much you would benefit from chemo and how much you would benefit from endocrine therapy. That said, endocrine therapy not only reduces your risk of recurrence, it reduces your risk of a second breast cancer. My MO told me that he thought my chances of getting a new breast cancer were greater than my chances of a recurrence, so doing endocrine therapy reduced my chances of both.


There are many AIs to choose from and there is also tamoxifen. There are also other things to do to mitigate the side effects. I would talk to your doctor and ask him what else you can do to help with the side effects and also see if you can try one of the other meds


Keep us posted!

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Aug 29, 2019 05:04PM obsolete wrote:

Hi Auburn, I can empathize with your aggressive surgeries and treatments, and I can appreciate how you are now feeling after an eventful year. Have you ever had any genetic testing performed?

From everything I've heard and read, letrozole is said to be the least gentle of the AI's, although I haven't been on it myself. You may wish to get a 2nd MO opinion and review your ER % and molecular subtype (Luminal A vs. Luminal B?) and any lympho-vascular invasion and proliferation rate. Has your MO been monitoring your estradiol (E2) testing, which might possibly warrant an aggressive AI?

https://community.breastcancer.org/forum/8/topics/...

There are supposedly alternative natural substances, one of which I take, but my scenario was different. I had Luminal A subtype, Grades I-II, multicentric & multiple MC turmors, in addition to a 3cm tumor of another subtype with a lower Oncotype DX score. I also had Grade-III, but it was non-invasive DCIS. Also had BMX following my original DX with lumpectomy.

https://www.ncbi.nlm.nih.gov/pubmed/24929094

https://suppversity.blogspot.com/2014/06/melatonin...

Personally, I had much preferred Tamoxifen over the AI (anastrozole) because I felt it was much gentler on my system, but I had been taken off Tamoxifen because it had supposedly contributed to PE blood clots in my lungs after a car accident. It had always helped me to seek 2nd opinions. Best wishes.















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Dec 11, 2019 10:59PM voraciousreader wrote:

https://www.ncbi.nlm.nih.gov/pubmed/31718120


HER 2 positive mucinous bc...

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Dec 11, 2019 11:01PM voraciousreader wrote:

https://www.ncbi.nlm.nih.gov/pubmed/31685005


radiation for PMC patients age 65 and over

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Dec 11, 2019 11:04PM voraciousreader wrote:

https://www.ncbi.nlm.nih.gov/pubmed/31620680

Pure mucinous bc compared to other rare types as well as mixed mucinous bc

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Dec 12, 2019 08:05AM Lime wrote:

Thank you Voracious! It was great to read this information as a refresher. One thing stood out in the Her2 article for my particular case. The presence of signet ring cells in Her2 mucinous has always been of interest to me all these years. Thanks again and best wishes to you and yours this holiday season

Dx 7/1/2011, IDC: Mucinous, Right, 2cm, Stage IIB, Grade 3, 2/14 nodes, ER+/PR+, HER2+ Chemotherapy 9/6/2011 Carboplatin (Paraplatin), Taxotere (docetaxel) Hormonal Therapy Arimidex (anastrozole) Targeted Therapy Herceptin (trastuzumab) Surgery Mastectomy: Right; Reconstruction (right): Nipple reconstruction, Silicone implant, Tissue expander placement
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Dec 12, 2019 06:09PM wobbly wrote:

I am in the uk...

I am 5 years out and have been told i can stop letrozole... We dont have the BCi on the nhs... I read smaller tumours come back later. Not sure what to do

Surgery 11/23/2014 Lumpectomy: Left Hormonal Therapy 2/1/2015 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy 2/8/2015 Breast Dx <1cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- Hormonal Therapy Femara (letrozole) Surgery Prophylactic ovary removal
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Dec 12, 2019 09:42PM voraciousreader wrote:

lime...Heart

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Dec 12, 2019 09:44PM voraciousreader wrote:

wobbly..this week is the annual San Antionio Breast Cancer Symposium....here is the latest which may help...please discuss this study with your team....


https://www.targetedonc.com/conference/sabcs-2019/preventative-breast-cancer-effect-maintained-with-anastrozole-in-longterm-followup-data

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Dec 13, 2019 01:46AM voraciousreader wrote:

i don’t recall if I have mentioned this link before....If I did, it certainly appears worth repeating


https://www.clinical-breast-cancer.com/article/S1526-8209(18)30393-8/fulltext



Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Dec 22, 2019 11:39AM dilloa wrote:

Hello

Kind of new to breastcancer.org. Participating and learning on behalf of my wife who was recently (2 weeks ago) diagnosed with BCa. She is 57 yrs old. For context...and forgive me for the long intro.......she is part of a regular screening program, (in Canada) mammogram every 2 years which started at age 50. In March 2018 an abnormal screening mammogram was repeated with a diagnostic mammogram and the conclusion was to resume normal screening; it was normal. Fast fwd. to Oct 2019, 17 months in between screening tests, and she discovers a lump in the upper outer quadrant of her right breast. In early December 2019, mammogram and ultrasound reveal a spiculated lesion of 2.1 cm. Biopsy results came back with a Grade i tumor, of the colloid type. ER+ at 100%, PR+ at 12% and HER2 NEG (Score 0).

We had the surgery consult last Wednesday with a very experienced oncology surgeon who does only breast surgery, over 500 per year. He was quite confident that this was an excellent prognosis cancer. In fact he said there was really only one better case which would have been a DCIS, but there could have been many worst cases that could have emerged from the biopsy. His prediction is that the oncotype score will be low and therefore chemo will likely be unnecessary. He also said that these cancers usually have a 90% probability that they will not invade lymph nodes. His prediction is surgery (lumpectomy) followed by radiation therapy and then 5 years of hormone therapy.

I am here now to learn from real patients with this condition. I will slowly read through the many posts and read the many articles. From what I have read, Mucinous tumors are sub-typed into types A & B and one is considered a more pure type whereas the other is a mixed type. I also understand that there is no medical guideline of what constitutes pure but that greater than 90% of cells being of mucinous type is the reference. Anything else would be considered mixed type which comes with a poorer prognosis than pure type.

The pathology report does not specify pure or mixed. It just states "of the colloid type"....the way the surgeon spoke, it sounded pure, but i am not sure about that unless the path reports normally would state "mixed type" if it was not pure.

I guess the purpose of this post is to hear back from people who have had a similar diagnosis, and learn what their experiences have been and to see if the real world matches the surgeon's optimistic prognosis. I want to believe it. But I am cautious to do so. I know everyone is different, everyone's tumor is different, and many factors can drive the outcome such as existing co-morbidities, genetics, lifestyle etc. While I read through the many posts already here, any feedback, especially if positive :) would be appreciated.

thank you

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Dec 22, 2019 12:42PM voraciousreader wrote:

so far, the info you have received from your team is on spot.while the PR is on the low side, it is still positive. The OncotypeDX score SHOULD validate the pathological features and also give your wife some good treatment choices.


And speaking of path report...all pathologists write differently...that said, when you meet with the oncologist ...ask them to tell you whether it is pure or mixed. They should know. Ad if even they are unsure, let them call the pathologist.


Keep us posted! We are here!

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Dec 23, 2019 12:04PM dilloa wrote:

thanks varaciousre

we will most definitely pursue to find out if pure vs mixed. Regarding the oncotype testing, i remember the surgeon very clearly stating that he was going to run the test only to provide another level of "insurance" or validation to his clinical diagnosis that chemo would not be required. He told us that because the mass had exceeded 2cm (was 2.1 cm) on ultrasound and because PR was 12%, the government would pay for the test (public healthcare in Canada). The doc was actually on the committee that formed the guidelines for when this test should be covered. He said that if PR is greater than 20% the test would not be covered given that she 100% ER+ and that its a grade 1 colloid type tumor.

I have started reading the posts in this thread and i must say it is very informative. The waiting is the hardest part !!

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Dec 23, 2019 12:32PM voraciousreader wrote:

glad you are finding this thread helpful. Try not burning the midnight oil reading it. The info you are getting and the advise is excellent.

Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Jan 9, 2020 12:24PM rain88 wrote:

Hello, ladies. Here I am, able to openly talk/write about my BC. It is hard! As I am writing, all logic and rational thoughts are gone; My hands are shaking and I am crying... but I am ok. If I can do this, then I will most likely be able to go back to normal, or... to the new normal. I know now I was fortunate that my BC turned out to be the mucinous kind. 5 months ago, at the age of 48, I knew nothing about BC! I cannot even believe I was so ignorant!

Since then, I have looked up all the words on my path. (Dx: Invasive Mucinous Carcinoma, DCIS, ALH. Initially, the results of the core needle biopsy were Invasive Breast Cancer with Mucinous Features.)

When I went in to see my family physician and he said I had BC, it took me a while to register that the lump I found myself was in fact malignant! Five years previously I had a biopsy of a lump in the opposite breast and it turned out to be benign. So, I was convinced that the newly found one would be of the same nature. I also had regular mammograms - since I have very dense breasts - and there had been no indication of the DCIS or the AHL, even though they most likely had been there for a while. Knowing the particular characteristics of a mucinous carcinoma now, I understand why everybody thought it was something benign. I wish they didn't express their certainty about it though. Imagine having all those scans and tests and people saying each time "Don't worry, it doesn't look like something bad". (In their defence, this BC being rather rare, they might have never even had a case of it until then...) Anyway, when my physician office called and said I needed to go in to talk about the results, I assumed it was standard practice for sharing a report and that my doctor prefered to see me instead of just telling me on the phone. Long story short, since then, I had lumpectomy, done 15/4 days of radiotherapy and just started on tamoxifen. I will have my first follow up in a few weeks and then I will move on from there.

I really consider myself fortunate, first of all because of the type of BC I had and then because of the amazing medical team involved in my treatment, beginning with my BS and continuing on with the lovely rads ladies! Luckily for me, I am not alone in fighting this dreadful disease. I have also drawn tremendous strength from all these wonderful people: my husband, my children, my sister, my friends, my coworkers. So, yes, most of the time I feel grateful for everything good bestowed upon me, for I know it could have been much worse. Having said that, it is not always that easy; there are times when I feel utterly alone and in bleak despair; that's when the gloomy shadow of BC is trying to creep out! I am doing everything in my power to stay positive and to focus on the good parts. However, I wouldn't be true to myself if I didn't admit that having been diagnosed with BC, no matter how favourable, I will always have this irrational fear of it coming back. I only hope and pray that when I feel like that, I will always have the strength to move beyond it.

May we all be in continuous health and pull through all the treacherous times we might encounter from now on.

Dx 7/2019, IDC: Mucinous, Right, 1cm, Stage IA, Grade 1, 0/10 nodes, ER+/PR+, HER2- Radiation Therapy 11/27/2019 Whole-breast: Breast Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lumpectomy: Right
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Jan 9, 2020 06:14PM tricianneAust wrote:

Blessings rain88, Its great when you can start talking about your MC openly. Now I am in my 10th year since having MC I don't even get distressed thinking or talking about it. I openly encourage my friends and contacts to talk about their fears & get themselves checked or double checked. I had my last mammogram in December & all is well so must update my info. I feel really well & encouraged by my improved health. My biggest concern now is climate change, the drought in Australia and all of our bushfires. Kangaroo Island just opposite Adelaide was in extreme fire conditions last night. We are all dealing with ash & bushfire haze which is nothing in comparison to what they are dealing with. Please pray that the rain comes today and is heavy & useful. Blessings on all my MC friends. Sorry I have been out of touch. Just too much else going on in life.


TricianneAust Dx: 10/20/2010, DCIS Pure Mucinous Cancer , 2cm, Stage I, Grade 1, 0/3 nodes, ER+75% /PR+ 75%, HER2-. Lumpectomy,Tamoxifen,25 x radiation, Vit D deficiency being treated. Dec 19 Mgram all ok.
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Jan 9, 2020 09:33PM rain88 wrote:

Hugs and prayers, Tricianne.

Dx 7/2019, IDC: Mucinous, Right, 1cm, Stage IA, Grade 1, 0/10 nodes, ER+/PR+, HER2- Radiation Therapy 11/27/2019 Whole-breast: Breast Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lumpectomy: Right
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Jan 26, 2020 11:51PM voraciousreader wrote:

https://www.ncbi.nlm.nih.gov/pubmed/31897333




Omission of Chemotherapy for the Treatment of Mucinous Breast Cancer: A Nationwide Study from the Korean Breast Cancer Society.
Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Jan 27, 2020 12:13AM voraciousreader wrote:

https://www.ncbi.nlm.nih.gov/pubmed/31685005



Omission of adjuvant radiotherapy following breast-conserving surgery for elderly women with early-stage pure mucinous breast carcinoma.
Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Jan 27, 2020 12:14AM voraciousreader wrote:

https://www.ncbi.nlm.nih.gov/pubmed/31718120



Clinicopathologic characteristics of HER2-positive pure mucinous carcinoma of the breast.




Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Jan 27, 2020 12:18AM voraciousreader wrote:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776130/





Comparison of Clinical Features and Treatment Results of Mix Mucinous Carcinomas and Other Atypical Carcinomas of the Breast
Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)
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Jan 27, 2020 02:55AM FeelingtheMagic wrote:

Hello all
I haven't posted for quite some time but want to thank all of you who contribute here. Voracious, thank you, especially for always staying on top of posts and providing such valuable information for everyone.
To all who are new here, I'm sorry that you have a reason to be here, but you have found a very supportive place with resources and information that is accurate. I know I was relieved I found this site when I was searching for answers.
Dilloa, I agree with Voracious that your team is spot on.
My update: 8 years since first being diagnosed. Happy when the A.I.'s were completed after 5 years, because they did play havoc with joint pain and brain fog. However, I did switch a few times on the type of A.I. prescribed until finding one that caused the least side effects. Don't be afraid to keep talking to your oncologist about your side effects. They are there to help you.
My ridiculous news is that I will be having my implant removed in March, because it is an Allergen product that has been recalled because it may cause a rare cancer. The mention of rare, with both my daughter and I having had rare cancers was less than reassuring for me, so I look forward to the explant and oh well to being half flat after! Hope that none of you are dealing with this, too.
Tricianne, I'm so sad for Australia - the people, the animals, and the land. Sending you extra love.
Good wishes to all for healing and happiness

DCIS and Pure mucinous and Her2+ WTF? (oops did I say that?) Dx 3/2/2012, Left, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ (FISH) Surgery 4/3/2012 Lumpectomy: Left Surgery 5/1/2012 Mastectomy: Left Targeted Therapy 6/24/2012 Herceptin (trastuzumab) Chemotherapy 6/24/2012 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 3/4/2013 Reconstruction (left)
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Jan 27, 2020 07:05AM tricianneAust wrote:

Hi all my MC sisters. It has taken me half the night to update my Signature in Settings I guess I am getting old & do not navigate this website as frequently as I did. Thanks for all the updates which I pray for you all as I quickly read them on the email notifications.

Feelingthemagic thankyou for your kind thoughts for those suffering in the bushfires but its a hard choice you are going through the implant risk causing you a one sided flattened bosom. So lots of prayers & blessings. Its been horrendous here but on the whole people are pulling together really well considering they have dealt with the worst bushfires ever. If you saw The Tour down under on TV you will see parts of the Adelaide Hills that suffered badly but other nearby areas are mainly unaffected except they are living in fear until summer is over about April when the bush fire risk decreases. My three families that live in the hills were evacuated but escaped damage. We have had some cooler safer weather for a couple of weeks that gives us all a chance to recover before the next heatwave. Blessings on you all Tricia

TricianneAust Dx: 10/20/2010, DCIS Pure Mucinous Cancer , 2cm, Stage I, Grade 1, 0/3 nodes, ER+75% /PR+ 75%, HER2-. Lumpectomy,Tamoxifen,25 x radiation, Vit D deficiency being treated. Dec 19 Mgram all ok.
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Jan 27, 2020 10:20AM voraciousreader wrote:

feeling...How awful! Really! You are living one of my nightmares! I had a hip replacement in 2018 and I SOMETIMES worry that my implant will be recalled. A lot easier when it is a car part being recalled! Good luck and thanks for chiming in!


trish...to you and the people down under, thoughts and prayers to all. My family lived through Superstorm Sandy and, six years later, the community is still recovering. Thankfully, my home was untouched...but so many friends and family are still picking up the pieces. I wish all of you a safe and swift recovery...


and, as always, Trish, thanks for your thoughts and prayers for all of our sisters...and brothers too. I know you are always praying for us and that means a whole lot!



Doctor told me regarding my prognosis that I WASN'T on the Titanic! Hmmm...Really?....Okay! 02/2010 Pure Mucinous Breast Cancer, Oncotype DX 15, Stage 1, Grade 1, 1.8 cm, 0/2 nodes, ER+ 90% /PR+ 70% HER2- (+1)

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