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Topic: Thyroid Cancer

Forum: Breast Cancer with Another Diagnosis or Comorbidity — Meet others who have breast cancer but also have another health diagnosis/comorbidity such as diabetes, MS, bipolar disorder, HIV or AIDS, Parkinson's Disorder, schizophrenia, etc.

Posted on: Jan 3, 2016 06:51PM

bellhouse7 wrote:

I had double mastectomy 3 weeks ago with right lumph node involvemt, during pet scan before surgery, thyroid cance was found, havingit removed tomorrow, is this separate type of cancer,a coincidence or what?


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Nov 5, 2019 08:01PM Spoonie77 wrote:

There is also this article as well:

Women with thyroid cancer have a higher risk of breast cancer

https://www.thyroid.org/patient-thyroid-information/ct-for-patients/january-2016/vol-1-issue-9-p-3/

"The study included women over the age of 18 enrolled in the SEER database between 1973 and 2011. A total of 707,678 women with breast cancer and 53,853 women with thyroid cancer were found in this database. Of the women with thyroid cancer, 1750 women had breast cancer after the diagnosis of thyroid cancer. The 10 year risk for breast cancer after thyroid cancer was calculated and compared to the 10 year risk in the general population. Also, information about the tumor histology, lymph node involvement, the use of radioactive iodine and traditional radiation treatment was available since 1990.

The 10 year risk for developing breast cancer was higher in the patients with a history of thyroid cancer. At age 40-49, the risk for breast cancer in patients with thyroid cancer was 5.6% compared with 1.5% in the general population. For 50-59 year old women, the risk was 12.8% vs. 2.4% in the general population. For 60-69 year-old women, the risk was 7.4% vs. 3.6% in the general population. Women in their 70's had a risk for 11.1% vs. 3.8% in the general population. Breast cancer developed on average 5 years after the thyroid cancer diagnosis. Patients who developed breast cancer after thyroid cancer were more likely to have follicular thyroid cancers than patients with thyroid cancer who did not develop breast cancer. More thyroid cancer survivors have estrogen receptor/progesterone receptor positive cancers and more mixed ductal and lobular invasive breast cancer types than the general population who develops breast cancer. Patients with thyroid cancer who develop breast cancer were younger than the average patient who develops breast cancer (age 58 vs. 61).

WHAT ARE THE IMPLICATIONS OF THIS STUDY?

This study confirms that women who have thyroid cancer are at increased risk for breast cancer, and the cancer is histologically different than the general. The cause of this increased risk was not able to be determined by this study and may be related to a genetic predisposition to cancer itself or environmental factors. These data indicate that women who survive thyroid cancer should have more frequent mammographic screening and breast exams to evaluate for breast cancer than the general population of women."


"Spoonie" who entered BC World @ 41. DXd w/MS & Thyroid Cancer @42. Treatment: LX/SLNB/RADs. Plan A: 5mg Tamox = 0 QOL. Plan B: OS/AI = Rare allergy to OS meds. Plan C: Only option left,  Diet & Exercise. PS: Not a dr, just a Googler. Dx 7/20/2018, IDC, Left, 3cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Dx 8/30/2018, DCIS, Left, 1cm, Stage 0, Grade 2 Surgery 8/30/2018 Lumpectomy: Left; Lymph node removal: Left, Sentinel Radiation Therapy 10/1/2018 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy 3/30/2019 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 7/2/2019 Zoladex (goserelin)
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Nov 5, 2019 08:02PM TB90 wrote:

I studied this correlation for six years. I found as many studies to challenge this as to support this. The great news is that thyroid cancer is highly curable. So when afflicted with both, thyroid cancer is the lesser of the threat by a huge margin. The association between radiation and thyroid cancer is also disputed. Until they find a reason for their claims, a correlation does not actually help. Once dx with cancer, we are at greater risk of most cancers. Close surveillance is key. Avoiding paranoia for me is another goal.

Dx 11/28/2013, DCIS, Grade 2 Surgery 12/18/2013 Mastectomy: Left Radiation Therapy 2/20/2014 Breast
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Nov 5, 2019 08:06PM - edited Nov 5, 2019 08:12PM by Spoonie77

Exactly, close surveillence. Which is something that seems lacking in many patients care, as none of my team informed me of my increased risk for other cancers or specifically Thyroid. It's just info and to me when they look at that many studies in a meta review, covering from the late 90's to 2011, seems like it's a good enough correlation for me to admit the facts they state.

ETA - if not for my family history and my actual Thyroid Cancer symtpoms, I have no idea when I would have discovered this cancer and who knows how far it may have spread or not spread by then. I'm just glad it's been found and I can take care of it now. Just another reason that shows family history and being your own advocate is highly important for teams to pay attention to IMO.

"Spoonie" who entered BC World @ 41. DXd w/MS & Thyroid Cancer @42. Treatment: LX/SLNB/RADs. Plan A: 5mg Tamox = 0 QOL. Plan B: OS/AI = Rare allergy to OS meds. Plan C: Only option left,  Diet & Exercise. PS: Not a dr, just a Googler. Dx 7/20/2018, IDC, Left, 3cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Dx 8/30/2018, DCIS, Left, 1cm, Stage 0, Grade 2 Surgery 8/30/2018 Lumpectomy: Left; Lymph node removal: Left, Sentinel Radiation Therapy 10/1/2018 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy 3/30/2019 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 7/2/2019 Zoladex (goserelin)
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Nov 5, 2019 08:10PM Spoonie77 wrote:

Another snippet...

"Furthermore, women with a history of breast cancer are at an increased risk for differentiated thyroid cancer. Despite sometimes conflicting results as to the magnitude and significance of this risk, the above meta-analysis demonstrates a clear association and increase in co-occurrence of these two malignancies. Although further studies are needed, clinicians should consider the increase in risk for second primary cancers when caring for these individuals.

The U.S. Preventative Services Task Force (USPSTF) currently recommends women begin biennial screening mammograms at age 50. For women between 40 to 50 years old, USPSTF recommends discussing the risks versus benefits of screening mammograms (86). Women with a previous history of thyroid cancer appear to be at an increased risk for breast cancer, perhaps via genetic susceptibility, a common receptor pathway, or both. Thus these women should be managed accordingly. For women with a history of thyroid cancer without breast cancer risk factors, a conservative but reasonable surveillance strategy would include initiating screening mammography at 40. Whether or not these women require earlier more aggressive surveillance such as annual breast MRIs in addition to mammograms remains to be seen.

While clinicians should be aware of this association in caring for thyroid and breast cancer survivors, the cause of this increase in risk remains unclear. Although surveillance bias is a possible explanation in two indolent malignancies, there is not direct screening in cancer survivors that would explain this increase in risk. This leads one to suspect a pathophysiologic reason for this increase in risk. A number of cell line and clinical studies suggest a common hormonal receptor pathway involving estrogen and/or TSH (42, 4960)."

"Spoonie" who entered BC World @ 41. DXd w/MS & Thyroid Cancer @42. Treatment: LX/SLNB/RADs. Plan A: 5mg Tamox = 0 QOL. Plan B: OS/AI = Rare allergy to OS meds. Plan C: Only option left,  Diet & Exercise. PS: Not a dr, just a Googler. Dx 7/20/2018, IDC, Left, 3cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Dx 8/30/2018, DCIS, Left, 1cm, Stage 0, Grade 2 Surgery 8/30/2018 Lumpectomy: Left; Lymph node removal: Left, Sentinel Radiation Therapy 10/1/2018 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy 3/30/2019 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 7/2/2019 Zoladex (goserelin)
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Jan 24, 2020 04:08PM Olma61 wrote:

just thought I would post an update. I put my endo appt off until this month. saw her about a week ago. Just from reading the US report, she said the description of the nodules didn’t sound very concerning. She is seeing me again in four months for another ultrasound and more blood work. She did not want to do the biopsy.

I am fine with this. We’ll see what the next ultrasound looks like and take it from there

10/30/2017 Xgeva for bone mets 5/31/2018 Taxol finished! "If one just keeps on walking, everything will be all right” - Kierkegaard Dx 8/3/2017, IDC, Right, 2cm, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2+ (IHC) Targeted Therapy 10/28/2017 Perjeta (pertuzumab) Targeted Therapy 10/28/2017 Herceptin (trastuzumab) Chemotherapy 10/29/2017 Taxol (paclitaxel) Hormonal Therapy 5/14/2018 Arimidex (anastrozole) Radiation Therapy 5/29/2019 External: Bone
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Jan 24, 2020 05:01PM marijen wrote:

Olma, what kind of bloodwork? I am being watched too but no bloodwork.


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Jan 24, 2020 06:19PM Olma61 wrote:

She will do a full thyroid panel. These tests measure the function of your thyroid by measuring the thyroid hormones in your blood. Bloodwork is NOT used to diagnose thyroid cancer but it does indicate whether or not your thyroid is functioning properly.

They test your blood for TSH, T3, T4 and I think a couple of other things.

10/30/2017 Xgeva for bone mets 5/31/2018 Taxol finished! "If one just keeps on walking, everything will be all right” - Kierkegaard Dx 8/3/2017, IDC, Right, 2cm, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2+ (IHC) Targeted Therapy 10/28/2017 Perjeta (pertuzumab) Targeted Therapy 10/28/2017 Herceptin (trastuzumab) Chemotherapy 10/29/2017 Taxol (paclitaxel) Hormonal Therapy 5/14/2018 Arimidex (anastrozole) Radiation Therapy 5/29/2019 External: Bone
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Jan 24, 2020 07:26PM TB90 wrote:

Bloodwork reflects how well your thyroid is working, but is not a diagnostic tool for cancer. Thyroid nodules are often monitored for years with nothing dramatic ever occurring. A high percentage of all persons have undiagnosed nodules. Definitely not a risk factor for cancer. But once they are found, they feel compelled to monitor. Wish mine had never been found. I received a Tirads 5 and thus had a complete thyroidectomy only to find out it was benign. I feel great on synthetic hormones so no real reason to complain. But would prefer to still have my thyroid. Slowly losing all my optional body parts. Lo

Dx 11/28/2013, DCIS, Grade 2 Surgery 12/18/2013 Mastectomy: Left Radiation Therapy 2/20/2014 Breast
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Jan 24, 2020 07:47PM marijen wrote:

Well I don't care what they say, I think with BC it’s more likely to get thyroid cancer.

Sorry you lost your thyroid TB90.


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Jan 25, 2020 01:05AM - edited Jan 25, 2020 02:33AM by Olma61

Yeah, I really don't want any unnecessary surgery and I wasn't too happy about the thought of getting a needle stuck in my neck for a biopsy, either. I am fine with "watch and wait" in my case.

Yes, blood work definitely doesn't diagnose thyroid cancer, in fact, don't most people with thyroid cancer have normal blood work, that's what I read?

But, I haven't had a thyroid panel since 2018 so she will do one at my next visit.

Best of luck to all. : )

10/30/2017 Xgeva for bone mets 5/31/2018 Taxol finished! "If one just keeps on walking, everything will be all right” - Kierkegaard Dx 8/3/2017, IDC, Right, 2cm, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2+ (IHC) Targeted Therapy 10/28/2017 Perjeta (pertuzumab) Targeted Therapy 10/28/2017 Herceptin (trastuzumab) Chemotherapy 10/29/2017 Taxol (paclitaxel) Hormonal Therapy 5/14/2018 Arimidex (anastrozole) Radiation Therapy 5/29/2019 External: Bone
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Jan 26, 2020 03:03AM SondraF wrote:

Question for the thyroid ladies - they are running this panel on me too this month due to some things I've complained about recently. My body temperature runs almost a full degree less than 'normal' which I understand can be normal for me. I tolerate cold well and prefer being cold, and have low-end blood pressure. Do the rest of you have a similar temperature situation?

I had a thyroid panel run in 2006 after 3 years of fatigue, probably brought on by overtraining. They said it was all 'in the normal range' and that was that but I never saw the numbers (was moving).

Dx 9/27/2019, IDC, Right, 5cm, Stage IV, metastasized to bone, Grade 3, ER+/PR+, HER2- Targeted Therapy 11/29/2019 Ibrance (palbociclib) Hormonal Therapy 11/29/2019 Femara (letrozole), Zoladex (goserelin)
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Jan 26, 2020 02:36PM Olma61 wrote:

Sondra - My temp is always normal in the doctors office and my blood pressure is high rather than low.

I cannot tolerate heat very well, I always dress in layers so I can take things off if I get too hot, but I think that's a menopause thing rather than a thyroid thing.



10/30/2017 Xgeva for bone mets 5/31/2018 Taxol finished! "If one just keeps on walking, everything will be all right” - Kierkegaard Dx 8/3/2017, IDC, Right, 2cm, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2+ (IHC) Targeted Therapy 10/28/2017 Perjeta (pertuzumab) Targeted Therapy 10/28/2017 Herceptin (trastuzumab) Chemotherapy 10/29/2017 Taxol (paclitaxel) Hormonal Therapy 5/14/2018 Arimidex (anastrozole) Radiation Therapy 5/29/2019 External: Bone
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Jan 26, 2020 02:42PM marijen wrote:

My temp is always low and I have cold intolerance. Low temp is normal for hypothyroidism. If you take your temp every morning before you get out if bed and it is low let your doc know. Sometimes the tests can be normal and you still have thyroid disease. Some doctors are very clueless about the thyroid. I know from experience.

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Jan 26, 2020 02:44PM marijen wrote:

Hypothyroidism signs and symptoms may include:

  • Fatigue
  • Increased sensitivity to cold
  • Constipation
  • Dry skin
  • Weight gain
  • Puffy face
  • Hoarseness
  • Muscle weakness
  • Elevated blood cholesterol level
  • Muscle aches, tenderness and stiffness
  • Pain, stiffness or swelling in your joints
  • Heavier than normal or irregular menstrual periods
  • Thinning hair
  • Slowed heart rate
  • Depression
  • Impaired memory
  • Enlarged thyroid gland (goiter)
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Jan 26, 2020 11:54PM Spoonie77 wrote:

all of my thyroid labs were in normal range (including Thyroglobulin & Calcitonin) yet i still had thyroid cancer. In both lobes despite imaging only showing it in the right one prior to my Thyroidectomy. Yes most people have undiagnosed nodules but better safe than sorry IMHO. Good luck ladies.


https://www.cancer.org/cancer/thyroid-cancer/detection-diagnosis-staging/how-diagnosed.html

"Spoonie" who entered BC World @ 41. DXd w/MS & Thyroid Cancer @42. Treatment: LX/SLNB/RADs. Plan A: 5mg Tamox = 0 QOL. Plan B: OS/AI = Rare allergy to OS meds. Plan C: Only option left,  Diet & Exercise. PS: Not a dr, just a Googler. Dx 7/20/2018, IDC, Left, 3cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Dx 8/30/2018, DCIS, Left, 1cm, Stage 0, Grade 2 Surgery 8/30/2018 Lumpectomy: Left; Lymph node removal: Left, Sentinel Radiation Therapy 10/1/2018 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy 3/30/2019 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 7/2/2019 Zoladex (goserelin)
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Jan 27, 2020 12:26AM marijen wrote:

Spoonie, did you have any new symptoms before they found thyroid cancer? Like pain or nausea ?


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Jan 27, 2020 10:39AM Spoonie77 wrote:

Marijen, I had new itching in my neck/throat and I was even more tired and more out of breath. I had chalked it up to starting 5mg Tamoxifen but when I went off of it and these didn't improve I knew it was unrelated to the med. These symptoms started about 4 months before the first nodule was found accidentally due to a severe allergic reaction to Zoladex. This caused my neck to swell so a Ultrasound was ordered. That's how the first discovered it. They then monitored it for 3 months but due to my family history of it I insisted on a biopsy and it came back cancerous.

"Spoonie" who entered BC World @ 41. DXd w/MS & Thyroid Cancer @42. Treatment: LX/SLNB/RADs. Plan A: 5mg Tamox = 0 QOL. Plan B: OS/AI = Rare allergy to OS meds. Plan C: Only option left,  Diet & Exercise. PS: Not a dr, just a Googler. Dx 7/20/2018, IDC, Left, 3cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH) Dx 8/30/2018, DCIS, Left, 1cm, Stage 0, Grade 2 Surgery 8/30/2018 Lumpectomy: Left; Lymph node removal: Left, Sentinel Radiation Therapy 10/1/2018 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy 3/30/2019 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Hormonal Therapy 7/2/2019 Zoladex (goserelin)
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Jan 27, 2020 12:36PM marijen wrote:

Thank you Spoonie77, I do remember that pic of your swollen neck. I'm so glad you pushed for a biopsy!

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Feb 7, 2020 03:43PM marijen wrote:

Well my thyroid antibodies came out high, free t4 a little high, free t3 low. I'm waiting on my new naturopath dr to explain what's next. Thyroid cancer is one possibility with high antibodies and otther unpleasant diseases. Maybe next week I'll hear something. It makes me mad that with two endocrinologists I never got these tests.

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Feb 7, 2020 05:51PM Yogatyme wrote:

marijen, you are right about having normal thyroid panel and still having thyroid disease. I have been treated for hypothyroidism for many years and while my PCP always does labs, she treats by my symptoms. I am highly reactive to Synthroid and it only takes a very short time before I know my levels are off.

Yogatyme Surgery 3/3/2019 Prophylactic ovary removal Dx 7/19/2019, IDC: Papillary, Right, <1cm, Stage IA, Grade 2, 0/5 nodes, ER+/PR+, HER2- Surgery 8/13/2019 Mastectomy: Left, Right

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