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Topic: Ca 27-29 Tumor Markers increasing

Forum: Stage II Breast Cancer — Meet, share and support others with Stage II Breast Cancer

Posted on: Sep 28, 2020 06:54PM

Kath1228 wrote:

I am freaking out! My oncologist does tumors markers as part of my regular bloodwork every 6 months or so. I have always been in a range of 12.5 to 17.5 on my CA 27-29 for the last 6 years. But my numbers have been increasing over the last 4 times (about a year and a half) from 13.6 to 20.6 on September 14. It jumped from 17.6 to the 20.6 number in just 4 months.

I know this is well within “normal” limits, with 38 being considered the upper range of normal. But it is not normal for ME!! I had to draw my oncologist’s attention to this upward trend and now she is having my bloodwork repeated on October 19th because of the trend. I am so terrified something is going on.

She did ask me how I was feeling the day I had my bloodwork done and I wasn’t feeling great and have been extremely stressed. I had a cold and/or very bad allergies - lots of nasal congestion and just not feeling great. It wasn’t COVID...I got tested because I was feeling so crummy.

My doctor said inflamed mucus membranes could throw the results off....but then I later spoke to her NP who then contradicted her and said that’s not true!!! What?! I was holding onto that as some hope....


Has anyone had an upward trend that was due to something other than your cancer returning...I am so nervous and frightened that I can barely function....and still have to wait three weeks for bloodwork. Just when I started making some plans in my life...selling our home and buying a new one...I feel like I tempted fate by making plans....


My CEA markers are fine and all other bloodwork CBC, CMP are totally normal. WBC was a little high for me 9.3 - but maybe I was fighting off an infection at the time....I need some hope that there could be some other reason for this increase in CA27-29....🙏🙏

Dx 11/7/2013, IDC, Left, 2cm, Stage IIA, Grade 2, 0/3 nodes, ER+/PR+, HER2- Surgery 12/4/2013 Lumpectomy: Left Radiation Therapy 1/22/2014 Whole-breast: Breast Hormonal Therapy 11/3/2014 Femara (letrozole)
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Posts 31 - 37 (37 total)

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Mar 23, 2021 02:09PM chapagonzo wrote:

I am five years post stage one breast cancer. Today I was told my tumor marker for CA 27- 29 went from 37 to 41.2.

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Mar 23, 2021 08:29PM MinusTwo wrote:

chap - tumor markers are only an indication and only if there is consistent, continuing change. Many docs won't even do the tests because of that. I wouldn't worry about a one time number change that small.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014
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Mar 23, 2021 08:55PM - edited Mar 23, 2021 08:56PM by sbelizabeth

Chap, have you had a recent infection or illness? Surgery? My oncologist wouldn't even draw tumor markers until I was a few weeks post-op because the inflammation would cause a little rise. When I moved I had to find a new oncologist, and he doesn't order tumor markers because they're unreliable and can lead to unnecessary worry.

pinkribbonandwheels.wordpress.... Dx 10/20/2011, IDC/IBC, Left, 1cm, Stage IIIA, Grade 2, 6/28 nodes, ER+/PR+, HER2- Chemotherapy 12/15/2011 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Surgery 4/18/2012 Mastectomy: Left Radiation Therapy 5/21/2012 Breast, Lymph nodes Hormonal Therapy 7/19/2012 Femara (letrozole) Surgery 4/15/2013 Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap
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Mar 23, 2021 10:28PM chapagonzo wrote:

my doctor has ordered cat scans on my lungs pelvis and abdomen. He is old school and this is his regiment. My anxiety has now hit an all time high.

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Mar 24, 2021 05:13AM - edited Mar 24, 2021 05:20AM by sbelizabeth

Has he been following your tumor markers since you were diagnosed? Have they always bounced around on the high side of normal, or does this 41.2 represent the highest of an upward trend?

I've never heard of an oncologist ordering full body scans with no other reason besides a single tumor marker result being a few points over the normal range.

pinkribbonandwheels.wordpress.... Dx 10/20/2011, IDC/IBC, Left, 1cm, Stage IIIA, Grade 2, 6/28 nodes, ER+/PR+, HER2- Chemotherapy 12/15/2011 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Surgery 4/18/2012 Mastectomy: Left Radiation Therapy 5/21/2012 Breast, Lymph nodes Hormonal Therapy 7/19/2012 Femara (letrozole) Surgery 4/15/2013 Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap
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Mar 24, 2021 08:32PM chapagonzo wrote:

I found out today that I was steady around 28. Last time InMarch 2020. Jumped to 38 in September 2020 then 41.2 in March 2021. So all still in or close to normal range there were two upward trends. The second being smaller than the first. I am five years out from stage one and it certainly has put my anxiety on a whole new planet.

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Mar 24, 2021 09:17PM sbelizabeth wrote:

Chapagonzo, scroll up in this thread and read the posts from women whose tumor markers were elevated because of recurrence or progression. Not only did they go up, they went WAY up, not just a few points. I understand your anxiety, particularly since your oncologist is concerned and ordering scans, but this little blip could easily be a reflection of a cold, a minor infection, or some other inflammation going on. Don't let it wreck your peace.

pinkribbonandwheels.wordpress.... Dx 10/20/2011, IDC/IBC, Left, 1cm, Stage IIIA, Grade 2, 6/28 nodes, ER+/PR+, HER2- Chemotherapy 12/15/2011 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Surgery 4/18/2012 Mastectomy: Left Radiation Therapy 5/21/2012 Breast, Lymph nodes Hormonal Therapy 7/19/2012 Femara (letrozole) Surgery 4/15/2013 Reconstruction (left): DIEP flap; Reconstruction (right): DIEP flap

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