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Topic: Oncotype Score for ER+/PR-

Forum: Diagnosed and Waiting for Test Results — Share with and support others all waiting for test results from CAT scan, PET scan, Oncotype tests, Mammaprint, FISH, IHC, and other diagnostic tests.

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Posted on: Mar 28, 2022 06:42PM

Posted on: Mar 28, 2022 06:42PM

kathabus wrote:

If you were highly ER+ but PR-, HER-....could you please post your Oncotype Score?

My mom was recently diagnosed with this and I'm curious about the range of scores.

I had a low score of 10, but I was highly positive for both. Thank you!

Dx 2/17/2020, IDC, Right, 2cm, Stage IB, Grade 2, 1/1 nodes, ER+/PR+, HER2- Surgery 3/23/2020 Lumpectomy; Lymph node removal Surgery 3/24/2020 Lumpectomy (Right); Lymph node removal (Right): Sentinel Surgery 5/1/2020 Radiation Therapy 5/14/2020 Whole breast: Breast, Lymph nodes, Chest wall Radiation Therapy 5/15/2020 Whole breast, Radiation boost: Right breast, Chest wall, Lymph nodes Hormonal Therapy 7/1/2020 Femara (letrozole) Surgery 7/20/2020 Hormonal Therapy 8/20/2020 Femara (letrozole)
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Mar 28, 2022 10:07PM murfy wrote:

Hi Kathabus, I was highly ER+ and PR- and had an Oncotype of 52. But as you'll see on some of the threads with this topic, there can be quite the range in scores. I wish you and your mom well...

Dx at 62: Oncotype=52; Path (ER=99%, PR=0%, Ki67=55%) Dx 10/2017, DCIS/IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER+/PR-, HER2- Surgery 11/13/2017 Mastectomy; Mastectomy (Left) Chemotherapy 12/1/2018 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy Aromasin (exemestane)
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Mar 29, 2022 12:42AM bailey5 wrote:

hi:

I’m not sure how high or low my ER+/PR- status was; but my oncotype score was 13 in 8/6/2010. I had BM w/tram flap reconstruction. I opted no chemo. Clean margins and negative sentinel node. Treated with Tamoxifen which was intolerable. Fast forward to 11/1/2017 when I was diagnosed with Mets lymph & lung. Immediately started tIbrance/Femara combo therapy. See Ibrance

Bailey5 Dx 6/1/2010, ILC/IDC, Left, 1cm, Stage IA, metastasized to lungs/other, Grade 1, 0/1 nodes, mets, ER+/PR+, HER2- Surgery 8/4/2010 Lymph node removal; Lymph node removal (Left): Sentinel; Mastectomy; Mastectomy (Left); Prophylactic mastectomy; Prophylactic mastectomy (Right); Reconstruction (Left): Free TRAM flap, Nipple reconstruction; Reconstruction (Right): Free TRAM flap, Nipple reconstruction
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Mar 29, 2022 03:50PM violet wrote:

Hi. I was was highly ER positive and PR negative in 2014. My recurrence score was 18-no chemo. I was on Arimidix for 7 years and was diagnosed with DCIS in 2020. I have since had bilateral mastectomy and reconstruction. Wishing you and your mom well.
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Mar 29, 2022 03:59PM melmatt wrote:

Hi—I was highly ER positive and PR negative. OncoType score was 17, no chemo. Hope that helps, and sending good thoughts for you and your mom

Dx 4/2019, LCIS/ILC, Left, 1cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR-, HER2-
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Mar 29, 2022 06:50PM kathabus wrote:

Thank you for all your responses. Even though it's all a crapshoot, it gives me an idea of where this is going. Bailey, I'm sorry to hear about the mets, but glad to see you are going on five years this year! Love to all...

Dx 2/17/2020, IDC, Right, 2cm, Stage IB, Grade 2, 1/1 nodes, ER+/PR+, HER2- Surgery 3/23/2020 Lumpectomy; Lymph node removal Surgery 3/24/2020 Lumpectomy (Right); Lymph node removal (Right): Sentinel Surgery 5/1/2020 Radiation Therapy 5/14/2020 Whole breast: Breast, Lymph nodes, Chest wall Radiation Therapy 5/15/2020 Whole breast, Radiation boost: Right breast, Chest wall, Lymph nodes Hormonal Therapy 7/1/2020 Femara (letrozole) Surgery 7/20/2020 Hormonal Therapy 8/20/2020 Femara (letrozole)
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Apr 1, 2022 01:40PM olympicmtgirl wrote:

Wishing your Mom a strong journey.

Received mine today ER 95> positive, PR <1% negative, HER2 +1 negative. Oncotype received today 15

Surgery 3/9/2022 Lymph node removal (Left); Mastectomy (Left): Simple; Mastectomy (Right): Simple; Prophylactic mastectomy (Right) Hormonal Therapy 4/1/2022 Femara (letrozole) Dx IDC, Left, 1cm, Stage IA, Grade 1, ER+/PR-, HER2-
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Apr 5, 2022 06:43AM kathabus wrote:

Thanks for all the responses...it's hard to wait sometimes. She got a 14. I found it interesting that the PR on the Oncotype was a "5.5" which is right on the border of being PR+. I wondered if that helped with getting a lower score. Thank you for all the good thoughts! Having gone through this (and let's face it....we are always going through this....) I realize that my survivor sisters are the only people who REALLY get the struggles. Hugs to all.

Dx 2/17/2020, IDC, Right, 2cm, Stage IB, Grade 2, 1/1 nodes, ER+/PR+, HER2- Surgery 3/23/2020 Lumpectomy; Lymph node removal Surgery 3/24/2020 Lumpectomy (Right); Lymph node removal (Right): Sentinel Surgery 5/1/2020 Radiation Therapy 5/14/2020 Whole breast: Breast, Lymph nodes, Chest wall Radiation Therapy 5/15/2020 Whole breast, Radiation boost: Right breast, Chest wall, Lymph nodes Hormonal Therapy 7/1/2020 Femara (letrozole) Surgery 7/20/2020 Hormonal Therapy 8/20/2020 Femara (letrozole)
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Apr 21, 2022 03:14PM noey69 wrote:

This thread caught my interest as I am awaiting oncotype score too. I've read some studies about ER+ PR- having a poorer diagnosis than if both were positive, so I've been a bit of a worry wart about it. It's been almost 3 weeks since they sent sample away to be tested. Still waiting.

Surgery 4/1/2022 Lumpectomy (Left); Lymph node removal (Left): Sentinel Radiation Therapy 4/1/2022 Left breast Hormonal Therapy 6/1/2022 Dx ILC, Left, 1cm, Grade 2, 1/6 nodes, ER+/PR-, HER2-

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