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Topic: Herceptin / Chemotherapy and Heart Damage?

Forum: Immunotherapy - Before, During, and After —

Discuss your experiences with the benefits, risks, and side effects of immunotherapy treatment for breast cancer.

Posted on: Nov 6, 2018 09:55AM

RebzAmy wrote:

Did anybody find out that their treatment had affected their heart some years down the line, and if so how? I'm currently being investigated for high blood pressure and a very fast heart rate (which started suddenly and resolved by the next day). I've had various tests and scans and am currently wearing a 24-hour heart trace monitor and a 24-hour blood pressure monitor. I had my treatment from 2007-2008. Thanks

Diagnosed June 2007, IDC, Grade 3, 4-5cm lump, several lymph nodes involved, HER2+++, 4 months of high strength chemo, mastectomy and lymph node removal, radiotherapy & a year of herceptin and recently had preventative surgery to other breast.
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Dec 19, 2018 11:08PM leftfootforward wrote:

Herceptin effected my heart- it lowered my ejection fraction of my left ventricle such that I was almost in co festive heart failure. I had to stop treatmentbwith herceptin. Fortunately, my heart function returned to normal over time.

I am on a beta blocker and ace inhibitor to help.

I tried herceptin again and same thing hapoened.

Good news is I recovered again.

Theee is a thicjeningbif mt heart muscle from all the meds.

I am still watched by a cardiooogist and have echo cardiograms about every 6 months.

Good luc

Dx 12/13/2010, IDC, 3cm, Stage IIIA, Grade 2, 1/16 nodes, ER-/PR-, HER2+ Dx 12/4/2012, IDC, Stage IV, 0/0 nodes, ER-/PR-, HER2+
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Dec 20, 2018 12:51AM illimae wrote:

I think about 12% have heart issues due to Herceptin but it tends to happen during active treatment. I do know of someone (triple negative), who developed heart damage due to the chemo drugs a couple years after completing their treatment.

Diagnosed at 41 Stage IV De Novo Dx 11/16/2016, IDC, Left, 5cm, Stage IV, metastasized to bone, Grade 3, 3/13 nodes, ER+/PR-, HER2+ (IHC) Chemotherapy 1/2/2017 Abraxane (albumin-bound or nab-paclitaxel) Targeted Therapy 1/2/2017 Herceptin (trastuzumab) Targeted Therapy 1/2/2017 Perjeta (pertuzumab) Surgery 6/26/2017 Lumpectomy: Left; Lymph node removal: Underarm/Axillary Radiation Therapy 8/10/2017 Breast, Lymph nodes Dx 10/5/2017, IDC, Left, 5cm, Stage IV, metastasized to brain, Grade 3, 3/13 nodes, ER+, HER2+ (IHC) Radiation Therapy 10/20/2017 External: Brain Radiation Therapy 4/18/2018 External: Brain Radiation Therapy 5/23/2019 External: Brain Surgery 1/22/2020 Radiation Therapy 2/17/2020 External: Brain Radiation Therapy 7/20/2020 External: Bone Radiation Therapy 12/4/2020 External: Brain Targeted Therapy Tukysa (tucatinib) Chemotherapy Xeloda (capecitabine) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)

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