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Topic: New to immunotherapy Tecentriq

Forum: Immunotherapy - Before, During, and After —

Discuss your experiences with the benefits, risks, and side effects of immunotherapy treatment for breast cancer.

Posted on: May 26, 2020 08:17PM

dlittkemann wrote:

Hi all

Hope you are all doing well tonight. Quick question. I was diagnosed with bone mets in February... started Abraxane and Tecentriq mar 4th. Had my 3 month scan and my oncologist said scan was ok. Cpl spots have grown a little bit but he said we see this w this drug. When the cells attach to cancer cells, this makes tumour look bit bigger. But he said Then second 3 mos scan should see no change or some shrinking even. Anyone else heard this? Just want to be sure. There is some info on google. They called it pseudo progressio

Dx 4/2018, DCIS/IDC, Right, 6cm+, Stage IIIB, ER-/PR-, HER2- Dx 4/2018, DCIS/IDC, Right, 6cm+, Stage IIIB, ER-/PR-, HER2- Chemotherapy 6/25/2018 Radiation Therapy 1/20/2019 Whole-breast: Breast, Lymph nodes, Chest wall Surgery Lumpectomy: Right; Lymph node removal: Underarm/Axillary; Mastectomy: Left, Right
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May 27, 2020 06:59AM - edited May 27, 2020 06:59AM by Moderators

dlittkemann, until other members jump in here with some responses, you may want to take a look at the article Tecentriq (atezolizumab): Side Effects, How it Works, and More from our main site.

Wishing you well,The Mods
To send a Private Message to the Mods: community.breastcancer.org/mem...
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Jun 2, 2020 03:35PM Sf2008 wrote:

Hello,

I hope you are feeling a bit better with your bone pain. I too, have mets in my back and sternum. After two months of receiving this treatment I wasnt feeling any better, I had pain and I was tired. I had progression in bones and treatment has been stopped. Radiation and medicial oncologist agreed. I dont know if that is helpful.

Dx 2/8/2018, IDC, Right, 2cm, Stage IIB, Grade 3, 2/8 nodes, ER-/PR-, HER2- Dx 2/28/2020, IDC, Right, 2cm, Stage IV, metastasized to brain/bone/lungs, Grade 3, 2/8 nodes, ER-/PR-, HER2- (IHC)
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Aug 24, 2020 10:07AM moth wrote:

Sf2008, sorry about your progression. what is your treatment now?

I take weekends off

Initial dx at 50. Seriously?? “Sometimes the future changes quickly and completely and we’re left with only the choice of what to do next." blog: Never Tell Me the Odds

Dx 12/2017, IDC, Left, 1cm, Stage IA, Grade 3, 0/5 nodes, ER-/PR-, HER2- (IHC) Surgery 12/12/2017 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 2/14/2018 AC + T (Taxol) Radiation Therapy 8/13/2018 Whole-breast: Breast Dx 2/2020, IDC, Stage IV, metastasized to liver/lungs, Grade 3, ER-/PR-, HER2- Chemotherapy 3/18/2020 Taxol (paclitaxel) Immunotherapy 3/19/2020 Tecentriq (atezolizumab) Chemotherapy 11/26/2020 Abraxane (albumin-bound or nab-paclitaxel) Dx 12/9/2020, IDC, Right, Stage IV, metastasized to lungs, Grade 3, ER+/PR-, HER2- (IHC) Radiation Therapy 12/9/2020 External Hormonal Therapy 12/16/2020 Femara (letrozole) Dx 1/28/2021, IDC, Left, Stage IV, metastasized to bone Radiation Therapy 3/3/2021 External: Bone
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Sep 10, 2020 05:50AM Stillhavehope wrote:

I was wondering what percentage was everyone’s PD-L1. Mine was 30%. My onc said that was high and I am wondering if that is a good thing? She seemed very positive about it

Dx 5/14/2014, IDC, Right, 5cm, Stage IIIA, metastasized to other, Grade 1, 5/13 nodes, ER+/PR+, HER2- Dx 6/2020, Stage IV, metastasized to other, ER-/PR-, HER2-
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Sep 12, 2020 03:31AM - edited Sep 12, 2020 03:32AM by Lulabelle2020

Mine is 2% the tests used in the uk rarely come up high as they only test the surface of the tumour whereas the more advanced tests include the inside of the tumour. I believe one cut off is 1% or over (the outer tumour) and one is the inner which is 10% so either way definitely good.

I'm yet to have my three month scan It should be after next weeks round. I have noticed differences softening of original tumour, skin mets are less but without having a scan I wouldn't know 100%.

i have some bone aches but I got them after my last chemo in the first line setting so monitoring it. My onc isn't keen to scan but then from the other people I've spoken to on immuno they have said aches and pain happen.

This is the most advanced treatment so far for TNBC mets so it is brilliant you can get it 😊

Love, light and healing 💕💖 Dx 3/29/2016, ILC, Right, 3cm, Stage IIIA, Grade 3, 3/9 nodes, ER-/PR-, HER2- Chemotherapy 7/22/2016 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Dx 7/1/2020, IBC, Right, 6cm+, Stage IV, metastasized to other, Grade 3, ER-/PR-, HER2- Chemotherapy 7/8/2020 Abraxane (albumin-bound or nab-paclitaxel) Immunotherapy 7/8/2020 Tecentriq (atezolizumab) Surgery 4/18/2021 Mastectomy: Right Radiation Therapy Whole-breast: Breast Surgery Lumpectomy: Right; Lymph node removal: Sentinel, Underarm/Axillary
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Sep 13, 2020 12:29PM Stillhavehope wrote:

I had a ct scan about a month after restarting Abraxane and had one dose of Tecentriq It showed measurable decrease of noodles in my lymph nodes in the omentum. I have no solid tumors but did have cancer cells in the fluid ofmy plural cavity. I’m hoping next ct scan is even better😊

Dx 5/14/2014, IDC, Right, 5cm, Stage IIIA, metastasized to other, Grade 1, 5/13 nodes, ER+/PR+, HER2- Dx 6/2020, Stage IV, metastasized to other, ER-/PR-, HER2-
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Sep 14, 2020 02:58AM Lulabelle2020 wrote:

yes that is good it seems to have quite an instant effect I guess it’s just hoping that it has a durable effect with longevity 😊

Love, light and healing 💕💖 Dx 3/29/2016, ILC, Right, 3cm, Stage IIIA, Grade 3, 3/9 nodes, ER-/PR-, HER2- Chemotherapy 7/22/2016 Cytoxan (cyclophosphamide), Ellence (epirubicin), Fluorouracil (5-fluorouracil, 5-FU, Adrucil) Dx 7/1/2020, IBC, Right, 6cm+, Stage IV, metastasized to other, Grade 3, ER-/PR-, HER2- Chemotherapy 7/8/2020 Abraxane (albumin-bound or nab-paclitaxel) Immunotherapy 7/8/2020 Tecentriq (atezolizumab) Surgery 4/18/2021 Mastectomy: Right Radiation Therapy Whole-breast: Breast Surgery Lumpectomy: Right; Lymph node removal: Sentinel, Underarm/Axillary

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