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Feb 13, 2022 06:34AM
Is Anyone taking Tucatinib with Herceptin only, no chemo??
I was on Kadcyla for the last 6 years, after I had progression on the Herceptin and Perjeta.
I have had to stop the Kadcyla as I've been diagnosed with cirrhosis of the liver, with portal hypertension, ascites, and esophageal varices. All of this presumably due to the cumulative effect of all the chemo I've had since my diagnosis 25 years ago.
I have asked my oncologist about going back on just the Herceptin and Perjeta, as it did keep me Ned for almost 3 years, but she was not keen on the idea, stating that you don't go back on something that you had progression on.
Any further chemotherapy could put me into acute liver failure, so I am researching like crazy trying to educate myself on what's out there before my next visit with my oncologist.
I've been off the Kadcyla since October, and my most recent pet scan on Wednesday showed that I am still thankfully NED. I've got labs this coming Monday, so more info to add to the equation.
I even contacted Seagen,the maker of Tukysa, looking for information on possible liver issues when just taking it with Herceptin, but they couldn't help me🤷
Any info at all is appreciated!
3/1997, IDC, Right, 4cm, Stage IIB, 5/36 nodes, ER+/PR-, HER2+
3/4/1997 Mastectomy; Mastectomy (Right)
11/6/2012 Taxotere (docetaxel)
1/6/2016 Kadcyla (T-DM1, ado-trastuzumab)