Topic: Perjeta/Herceptin Side Effects - Itching face, fine bumps

Forum: Immunotherapy - Before, During, and After — Discuss your experiences with the benefits, risks, and side effects of immunotherapy treatment for breast cancer.

Posted on: Jun 28, 2022 02:47PM

Posted on: Jun 28, 2022 02:47PM

chuckee1104 wrote:

HI all,

Completed chemo in April 2022, but still on Perjeta/Herceptin until January. Just completed C8 last week and now face is itching and I have small bumps (didn't have this before, but I think a nurse warned me that this could happen). The nurse said to use hydrocortisone or Benadryl. Overuse of hydrocortisone also causes itching, burning and fine bumps AND Benadryl makes me sleepy so can only take at night. Has anyone else had these SE's? If so what did you use to treat it other than hydrocortisone and Benadryl? Aquaphor helps some, but there has to be another way...

Immunotherapy 1/25/2022 Chemotherapy 1/25/2022 Taxotere (docetaxel), Carboplatin (Paraplatin) Chemotherapy 1/25/2022 Other
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Jun 28, 2022 05:51PM serenitystat wrote:

I have no experience with this. You get better search results if you use your browser to search this site using the text below. herceptin+itch

Hope it helps.

🌻 🇺🇦 BCO leaked our private data. 🤦🏻‍♀️🤷🏻‍♀️ . . . . . "Do not overlook the little joys!" (Hesse, 1905) 🐶Dx.11/2015.IDC.L.IIIC.10/11nodes.++- ☕️12/2015.L.Mast 🛀2/2016.4AC.12Taxol.fasted 🖼9/2016.Rads.Nodes.ChestWall.15+4boosts 🥐10/2016.Tamox(2.5y) 🌲4/2019.Exemestane 🎭12/2019.Ibrance/Xgeva 🕊
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Jun 28, 2022 06:40PM olma61 wrote:

I got the small bumps on my face and terrible itching the first few weeks on H&P. Luckily, both side effects went away on their own, although the itching comes back now and then, luckily it has never been on the face because I have lightly scarred myself from scratching.

Here are things I have tried with varying levels of success to quell the itch:

BioFreeze spray - sometimes very effective but its messy and probably not good on the face,

Lidocaine in a tube 4% I think it is, brand name is Curacaine, worked really well for a while,

Clear calamine lotion

Various roll on 'freeze' preparations with menthol in them

Cold packs, ice, etc - freezing works well for me but the itch starts back pretty soon after removing the ice pad

Diphenhydramine tablets, they can make you sleepy

Claritin, dont know if it helps control the itching but I started taking it daily for the runny nose & watery eyes side effect.

Good luck, if it continues and is severe, your doctor should be able to prescribe something for you. almost five years on the drug now and although the itch has come and gone it is not constant, only sporadic

10/30/2017 Xgeva for bone mets 5/31/2018 Taxol finished! "If one just keeps on walking, everything will be all right” - Kierkegaard Dx 8/3/2017, IDC, Right, 2cm, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2+, IHC Targeted Therapy 10/28/2017 Perjeta (pertuzumab) Targeted Therapy 10/28/2017 Herceptin (trastuzumab) Chemotherapy 10/30/2017 Taxol (paclitaxel) Hormonal Therapy 5/14/2018 Arimidex (anastrozole) Radiation Therapy 5/30/2019 External Local Metastases 5/30/2019 Radiation therapy: Bone

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