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Topic: FDA Approves Tukysa for Advanced HER2+ BC

Forum: Stage IV/Metastatic Breast Cancer, Open to All To Contribute —

Topics here are started by members with a Stage IV/Metastatic Breast Cancer diagnosis, but open to all members to contribute to discussions. Please note that there is a separate forum, Stage IV/Metastatic Breast Cancer ONLY, where topics are open only to those members.

Posted on: Apr 22, 2020 04:10PM - edited Apr 22, 2020 05:16PM by Moderators

Moderators wrote:

Have you been diagnosed with advanced-stage HER2-positive breast cancer that has been treated with at least once anti-HER2 regimen and are considering which treatments to try next? On April 17, 2020, the FDA approved Tukysa (chemical name: tucatinib) in combination with Herceptin and Xeloda to treat metastatic HER2-positive breast cancer or locally-advanced HER2-positive disease that can't be completely removed with surgery.

Read the breaking news story here, and leave your comments below.

Read more about Tukysa (chemical name: tucatinib).

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Apr 22, 2020 05:00PM ShetlandPony wrote:

This is tucatinib, by the way.

2011 Stage I ITCs sn, premenopausal, Oncotype 16. 2014 Stage IV mets breast,liver. TaxolNEAD. Ibrance+letrozole 2yrs. Fas+afinitor nope. XelodaNEAD 2yrs. Eribulin,Doxil nope. SUMMIT FaslodexHerceptinNeratinib for Her2mut NEAD 1 1/2yrs. GI/perit mets Dx 2011, ILC, 1cm, Stage IA, Grade 1, 0/1 nodes, ER+/PR+, HER2- Dx 2014, ILC, 2cm, Stage IV, metastasized to liver/other, Grade 2, ER+/PR+, HER2- Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Radiation Therapy Whole-breast: Breast Surgery Lumpectomy

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