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Topic: Biopsy tested +ve for HER2.

Forum: Stage IV/Metastatic Breast Cancer, Open to All To Contribute —

Topics here are started by members with a Stage IV/Metastatic Breast Cancer diagnosis, but open to all members to contribute to discussions. Please note that there is a separate forum, Stage IV/Metastatic Breast Cancer ONLY, where topics are open only to those members.

Posted on: May 20, 2021 05:10PM

Koushik wrote:

Hi All,

If a biopsy sample from Breast is tested positive for HER2 protein. The disease that is spread to other Body parts is assumed to be tested positive for the same type?, or is it mandatory that other body parts samples should also be tested at one point of time?

Thanks All.

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May 23, 2021 04:43AM - edited May 23, 2021 04:44AM by Olma61

I do not know if it is mandatory or always necessary but I believe the MO often does order a biopsy to confirm that what is seen on scans is actually cancer. And at the time, the pathologist also tests for the ER/PR/HER2 status, of the metastatic tumor.

It will also depend on how accessible the mets are, in other words is it even possible to safelyget a sample

10/30/2017 Xgeva for bone mets 5/31/2018 Taxol finished! "If one just keeps on walking, everything will be all right” - Kierkegaard Dx 8/3/2017, IDC, Right, 2cm, Stage IV, metastasized to bone, Grade 2, ER+/PR+, HER2+ (IHC) Targeted Therapy 10/28/2017 Perjeta (pertuzumab) Targeted Therapy 10/28/2017 Herceptin (trastuzumab) Chemotherapy 10/29/2017 Taxol (paclitaxel) Hormonal Therapy 5/14/2018 Arimidex (anastrozole) Radiation Therapy 5/29/2019 External: Bone

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