Topic: Any high Ki67 survivor stories out there?

Forum: Who or What Inspires You? — Share your personal story, diagnosis, and treatment path, and stories of survival, hope, and success to encourage and inspire others!

Posted on: Mar 2, 2012 12:43PM - edited Mar 2, 2012 12:44PM by jenlee

Posted on: Mar 2, 2012 12:43PM - edited Mar 2, 2012 12:44PM by jenlee

jenlee wrote:

I would LOVE to hear from ANY survivors who had high Ki67 !!!!  (Also hormone positive with high Ki67).  My Ki67 is 75%, which feels like a death sentence, even though half way through chemo, the tumor has shrunk by about 80%.  It has been an emotionally challenging week and I could use some positive (really positive) stories.
Jenifer, completed TAC x 8 on 4/24/2012. Lumpectomy on 5/23/2012. BMX & immediate DIEH stage 1 on 6/5/2012 NOLA; stage 2 surgery 10/4/12 NOLA. Tamoxifen since 6/2012. Switched to Arimidex 9/2013. Dx 10/20/2011, IDC, 4cm, Stage IIA, Grade 2, 0/1 nodes, ER+/PR+, HER2-
Log in to post a reply

Page 3 of 5 (42 results)

Log in to post a reply

Apr 23, 2012 11:33AM - edited Aug 27, 2013 07:50AM by lisaellen

This Post was deleted by lisaellen.
Dx 3-18-07,2.2cm tumor,stageII,grade3,8 rounds ACT,no rads,Infiltrating ductal,0nodes, bi-latmast.10-07,expanders2-27-08, implants with tattoo nipples
Log in to post a reply

Apr 23, 2012 05:43PM lintrollerderby wrote:

I'm not quite a year from diagnosis; I had my last chemo the end of August. My KI-67 was 76%. It is scary, but I take hope that many women are several years out with higher scores than mine. I hope to be one of them.

Good luck to you!

Diagnosed at age 34 on 11 May 2011 • IDC • Right • 1.3 cm • Stage I • Grade 3 • 0/3 nodes • ER-/PR-/HER2- • Triple Negative and Basal-Like • Ki-67: 76% • P53: 64% • BRCA1+ (no family history) • BRCA1 mutation: IVS5-11T>G (known deleterious mutation) Surgery 4/27/2011 Lumpectomy: Right Surgery 5/30/2011 Lumpectomy: Right; Lymph node removal: Right, Sentinel Chemotherapy 6/22/2011 Cytoxan (cyclophosphamide), Taxotere (docetaxel)
Log in to post a reply

Apr 24, 2012 07:59PM christina1961 wrote:

Mine was 50% - I am about 14 months post diagnosis.

Dx 2/5/2011, IDC, 2cm, Stage IIB, Grade 3, 2/16 nodes, ER+/PR-, HER2-
Log in to post a reply

May 3, 2012 05:29AM weesa wrote:

My ki67 was 75%. Almost ten years out.

Sometimes I wonder if I am an old soul temporarily trapped in a breast cancer body. Dx 11/22/2002, IDC, 6cm+, Stage IIIA, Grade 2, 5/25 nodes, ER+/PR+, HER2- Chemotherapy 1/19/2003 Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy 6/13/2003 Breast, Lymph nodes Hormonal Therapy 8/22/2003 Femara (letrozole) Surgery Lumpectomy: Right; Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Right; Reconstruction (right): Latissimus dorsi flap
Log in to post a reply

May 5, 2012 06:18PM - edited May 5, 2012 06:18PM by jenlee

Weesa, that gives me happy tears!!!!!!

Thank you so much for your post -- I'm sure everyone on this thread appreciates it!

Jenifer, completed TAC x 8 on 4/24/2012. Lumpectomy on 5/23/2012. BMX & immediate DIEH stage 1 on 6/5/2012 NOLA; stage 2 surgery 10/4/12 NOLA. Tamoxifen since 6/2012. Switched to Arimidex 9/2013. Dx 10/20/2011, IDC, 4cm, Stage IIA, Grade 2, 0/1 nodes, ER+/PR+, HER2-
Log in to post a reply

May 5, 2012 06:22PM suemed8749 wrote:

Thanks to everybody posting here with their stories.

I was dx in Jan. 2008 - ki67 50%. Best wishes to you all.

Dx 1/15/2008, IDC, 2cm, Stage IIA, Grade 3, 0/3 nodes, ER-/PR-, HER2+
Log in to post a reply

May 7, 2012 01:59PM jenlee wrote:

thanks for suemedd for posting and congratulations on doing well!

Jenifer, completed TAC x 8 on 4/24/2012. Lumpectomy on 5/23/2012. BMX & immediate DIEH stage 1 on 6/5/2012 NOLA; stage 2 surgery 10/4/12 NOLA. Tamoxifen since 6/2012. Switched to Arimidex 9/2013. Dx 10/20/2011, IDC, 4cm, Stage IIA, Grade 2, 0/1 nodes, ER+/PR+, HER2-
Log in to post a reply

May 7, 2012 03:01PM MsBliss wrote:

ki67 is but one feature that factors into prognosis; many other features can balance what looks like an aggressive little cell....but if you look at my siggy line, I had a ki67 of 70 -90%. It was 70% in some areas, 90% in others. Triple negative, grade 3 on one scale, grade 9 on Nottingham. The first pathologist who looked at my biopsy was more than a bit alarmed at what she saw, so much so, that she picked up the phone and called the surgeon before filing her report. There was nothing mild about my tumor. I just passed my three year primary lumpectomy anniversary in March.

Dx 3/09 Triple negative, stg1, SNB0/2, BRCA neg, CHEK 2 pos, 1.4cm plus 7mm DCIS, ki67 70-90%, lumpectomy w/re-excision, no chemo/no rads due to delays from secondary health issues; evidence based interventions.
Log in to post a reply

Jul 19, 2012 03:17PM JFV wrote:

Hi !  My KI 67 score was 98% !  Grade 3, stage 3 ER, PR positive.  I also had three types of BC roaming aroun my breasts.  But, I'm still here two years later.  Became very friendly with 11 women from this board who went through chemo the same time I did.  We are all still alive and kicking.

Dx 3/18/2010, ILC, 3cm, Stage IIIA, Grade 3, 5/17 nodes, ER+/PR+, HER2- Surgery 4/19/2010 Mastectomy: Left, Right; Reconstruction (left); Reconstruction (right) Chemotherapy 6/14/2010 AC + T (Taxol) Hormonal Therapy 9/30/2010 Aromasin (exemestane) Radiation Therapy 9/30/2010 Breast, Lymph nodes Dx 4/2017, Stage IV, metastasized to bone, ER+/PR-, HER2- Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant)
Log in to post a reply

Jun 6, 2013 07:19PM kencooperjr wrote:

I realize this forum may not be quite the fit for this question but based on the topic and responses i have seen it may help.

My wife has quite recently been diagnosed with breast cancer (IDC) with an overall grade of 1. After surgery the pathology report indicated the tumor size as 8mmx7mmx6mm. Five sentinal lymph nodes were examined and all five were without tumor cells.

The following data were defined at the initial biopsy: ER: 100%, HR: 100%, Her2/neu: 1.2, Ki-67: 8%

The after surgery pathology report is: ER: 96%, HR: 100%, Her2/neu: 0.8, Ki-67: 42%

Surgery was almost two weeks after the biopsy.

The numbers are close except for the Ki-67 wherein the after surgery value is about five times the initial biopsy value!

I am wondering is the Ki-67 index of REAL use in determining if one needs chemo or not. We had assumed radiation and hormone treatment then the Ki-67 value in what seems to be an outlier has thrown all of this initial thoughts upside down with the possibility of chemo. As I have read the forum replies and a considerable amount of other data/information I see some doctors don't even have this test in the pathology report, some have it but it is not used to determine treatment and some use it - Arrgh.

Thanks for any thoughts and comments - Ken

Ken Cooper - for my wife Dx 5/6/2013, IDC, <1cm, Stage I, Grade 1, 0/5 nodes, ER+/PR+

Page 3 of 5 (42 results)

Scroll to top button