Topic: Fertility drug connection???

Forum: High Risk for Breast Cancer — Due to family history, genetics, or other factors.

Posted on: May 8, 2012 07:45AM

Posted on: May 8, 2012 07:45AM

number5 wrote:

Hello all!  Since reading so many different forums regarding pain in BC (such as docs saying you don't get pain in BC), being 'too young' to get BC, and other sorts of dismissive things docs say-and the uninformed in general!

Let me begin by saying I do NOT have breast cancer!  I've had breast issues the past three years with having a surgical biopsy (B9), microcalcifications, and most recently (yesterday), scheduling a diagnostic mammogram because something showed up on my annual mammo last Thursday!  I've had a cyst for many years that prompted a mammogram at the age of 23-it was finally drained after my sisters BC diagnosis 7 years ago!  I'm 46 now!!

Which brings me to my subject:  How many on here that are dealing with BC, used fertility drugs?  I have 3 sisters (and 5 bros), and my sister is the ONLY person in our entire family (cousins,aunts, uncles,etc.,) that has had any form of cancer!  She and I both used fertility drugs-our other two sisters and Mom had no problems conceiving naturally, and alas, none of them have had any issues when it comes to the breasts!

Now I know that hormones are a big factor!  I'm personally on BHRT progesterone after having blood and saliva test that showed my progesterone very, very low, and my estrogen 300 times that of my progesterone!  But does all of this, plus fertility drugs play a role?

Going back, my sister and former BIL went through several rounds of IUI-both with my BIL's sperm (which was a low count), and with donor sperm-no avail!  I used Clomid for several months, did 4 rounds of IUI, and then one round (very successful-three babies later), of IVF!  That's A LOT of hormones all at once-and my body knew it!

So, anybody else out there feel there's a connection?  Don't get me wrong, if I had to I'd do it all over again, but I just wonder if there IS a connection!  Thanks for reading!

J

Log in to post a reply

Page 1 of 5 (49 results)

Log in to post a reply

May 8, 2012 07:52AM - edited May 8, 2012 07:53AM by Momof2inME

I do think there is a connection. I did 4 rounds of clomid and 3 IUI's. Have 2 beautiful children that I wouldn't trade for anything. I'm 37 and stage 3. Found my lump 3 months after my son turned 1 and I stopped nursing. I don't know what the connection is whether its the fertility drugs, the subsequent pregnancies, or both. But I do believe something surrounding fertility contributed or "turned on" my bc. I have connected with several women on here that had fertility treatements as well then discovered they had bc. Some while pregnant.

Dx 11/30/2011, IDC, 1cm, Stage IIIA, Grade 3, 4/27 nodes, ER+/PR+, HER2+ Surgery 12/21/2011 Lymph node removal: Left; Mastectomy: Left, Right; Prophylactic mastectomy: Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 1/9/2012 AC Targeted Therapy 3/7/2012 Herceptin (trastuzumab) Chemotherapy 3/7/2012 Taxol (paclitaxel) Surgery 6/6/2012 Reconstruction (left); Reconstruction (right) Radiation Therapy 6/25/2012 Hormonal Therapy 8/6/2012
Log in to post a reply

May 8, 2012 08:00AM nancyhb wrote:

I would love to see a study of this, because I was a gestational surrogate for friends 14 years ago and went through two rounds of multiple hormones to turn things on/off before ZIFT and GIFT.  Second set of treatments resulted in a pregnancy.  If I remember correctly I had to do a lot of hormones to sync my cycle with the egg donor while also turning off my ovaries.  Even before seeing this thread, I have wondered if that had anything to do with this, especially since my cancer is ER+. 

I am not, in any way, shape or form, suggesting that women who use fertility treatments are going to get BC - there are so many potential contributing factors, and if we *knew* what caused this we wouldn't all be still trying to figure it out.  But for me, I have sincerely wondered if it was a contributing factor.

Nancy

"Be happy for this moment. This moment is your life." - Omar Khayyam Dx 11/22/2011, IDC, Left, 1cm, Grade 2, ER+/PR-, HER2- Surgery 12/5/2011 Lumpectomy; Lumpectomy (Left); Lymph node removal Chemotherapy 1/19/2012 AC + T (Taxol) Radiation Therapy 6/12/2012 Whole breast: Breast, Lymph nodes Dx 1/27/2016, IDC, Left, 1cm, Grade 3, 0/4 nodes, ER-/PR-, HER2- Surgery 2/15/2016 Lumpectomy; Lymph node removal; Lymph node removal (Left) Chemotherapy 3/1/2016 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Surgery 7/21/2016 Mastectomy; Mastectomy (Left); Reconstruction (Left): DIEP flap Dx 1/31/2017, IDC, Stage IV, metastasized to bone, HER2-
Log in to post a reply

May 8, 2012 08:10AM - edited May 8, 2012 08:11AM by SelenaWolf

It's hard to say.  My sister went through several years of fertility treatment with some pretty, heavy-duty drugs nearly twenty-five years ago and - thus far - she's okay.  Me, on-the-other hand, struggled not to get pregnant for twenty-five years and did develop breast cancer.

"... good girls never made history ..."
Log in to post a reply

May 8, 2012 08:17AM lroz0416 wrote:

Yeah - I'm with you on that. Although most research concludes that fertility drugs do not increase one's chances of getting BC, I think the verdict is still out on this. I remember reading something somewhere that said there needs to be more studies done that follow women who have had IVF treatments for a longer period of time. My hubby and I are trying to get pregnant and if we can't conceive naturally, we will definitely do fertility treatments. This is a topic of interest to me and I'll be curious to see what others have to say. Good luck to you w/ the diagnostic mammogram. It's always so scary when you have to go back for a 2nd or 3rd look, but atleast they're on top of it! Blessings :)

Log in to post a reply

May 8, 2012 08:28AM - edited May 8, 2012 08:29AM by SelenaWolf

I have, also, recently seen a news documentary that suggested IVF children are developing more serious, health issues over the long-term than the general population.  I don't know what they used as their references, but it was a sobering thought!  I have to wonder, though; if it's media-hype or solid research?

"... good girls never made history ..."
Log in to post a reply

May 8, 2012 08:52AM Shachar wrote:

I used Clomid for a year before conceiving my first child.  Seems I probably didn't need it because I then went on to have three more without and planning or problems.   Interesting....

Dx 4/23/2012, IDC, 6cm+, Stage IIIC, Grade 1, ER+/PR+, HER2-
Log in to post a reply

May 8, 2012 11:40AM number5 wrote:

Ciao again!  I would never discourage anybody from using fertility drugs-they helped make my dream come true!:-)  I wonder though if there is something there that some of us have in us that is triggered by certain things!  We never know if we're allergic to something until we are exposed, yet that's how we find out-but we still go about our lives before that, even though we know other people are allergic!

I too would like to see some study or the other regarding this-though I'm afraid if they did one, people would back away from the dream of getting pregnant with the use of fertility drugs!

These are the things I think of when I'm pondering the why BC has affected so many people!

Grazie!! J

Log in to post a reply

May 8, 2012 11:45AM number5 wrote:

@Selenawolf:  Knock on wood, my three IVF boys are doing just fine-thank goodness!  My twins (who will be 12 in 2 weeks), were born 8 weeks premature, but you'd never know it by looking at them (even at birth).  My youngest will be 9 next week, and he too is doing very well! 

I was told many years ago that IVF babies had a tendency to have more health/educational issues, but I don't know if that's because there are more multiples during one pregancy with many IVF pregnancies-or what the deal is!  My boys have thankfully thrived, as well as my eldest who was adopted at birth!  Now I have a new teen, and two on the edge!  Mamma mia! :-)

J

Log in to post a reply

May 8, 2012 11:51AM RebzAmy wrote:

I was an egg donor for somebody - I went through the whole process three times for them which meant my body was flooded with hormones, firstly to do something called down regulating so that the person I was donating to was in synch with my body and my cycle, then I had to inject myself daily for 2-3 weeks (can't remember now) and finally the egg collection. It was a few months after the final collection I was diagnosed with breast cancer however mine was HER2+. In relation to the person I was donating to, this was a good thing because had it been hormonal cancer, they would have felt it may have been due to what I'd been through for them that caused this to happen but who knows!

R

Diagnosed June 2007, IDC, Grade 3, 4-5cm lump, several lymph nodes involved, HER2+++, 4 months of high strength chemo, mastectomy and lymph node removal, radiotherapy & a year of herceptin and recently had preventative surgery to other breast.
Log in to post a reply

May 8, 2012 06:52PM SelenaWolf wrote:

@number5...My sister's first (IVF) has thrived, as well.  Nothing wrong with that boy; he's a genius!!  (Biased aunt here.)  It was funny; though, after 15 years of fertility treatments and failures, my sister had her first by IVF.  Then, when her first was 8 months old, WHAMMO!!!  She's, suddenly, pregnant with her second.  Came out of the blue; no-one was expecting it... least of all her!
"... good girls never made history ..."

Page 1 of 5 (49 results)

Scroll to top button