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Mar 4, 2019 06:59PM
I think it's very standard for premenopausal women with hormone receptor positive cancer to get tamoxifen.
For a higher risk case, doctors might recommend Ovarian Suppression PLUS Aromatase Inhibitor. This has been shown to be more promising for PR- cancer and and over all. It effectively puts you into menopause and drastically lowers any estrogen in your body. It's not recommended for all cases because of the side effect profile, is my understanding.
To me, removing of ovaries and uterus is, on the one hand, a step more drastic than ovarian suppression, and on the other hand, seemingly missing the Aromatase Inhibitor part that really makes a big difference.
I can't imagine how confusing it would be to see so many doctors and get so many different recommendations without really informative explanations.
I suppose that if a premenopausal woman were strongly opposed to taking any anti-hormonal therapy, then putting her in menopause would give her significantly more protection than nothing at all.
Are you opposed to hormonal therapy, or is the availability limited in your home country? That might be impacting your recommendations.
Dx at 39. 1.8cm. Oncotype 9.
9/19/2018, IDC, Right, 1cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- (FISH)
10/17/2018 Lumpectomy; Lymph node removal: Sentinel
11/1/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
12/2/2018 Whole-breast: Breast
12/18/2019 Fareston (toremifene)