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Nov 22, 2021 03:44AM
There are a few such tests but none of them have been adopted as part of the standard of care by my cancer center.
One of my sisters wants me to get this one:
Galleri Cancer Test
I believe it's not FDA approved.
I would love to know with more certainty whether or not there is still cancer in me.
If I did have one of these tests and it was positive, as was a retest, then a few questions would arise.
If head and chest MRIs and ultrasounds fail to find anything, and a nuclear bone scan and chest CT find nothing. Do we do a full body PET/CT?
If so, that would be two nuclear bone scans, three PET scans, two partial body CTs and two full body CTs in my lifetime, as well as a number of chest x-rays, and that works out to a statistically significant amount of radiation exposure, and a non negligible cancer risk from it.
What if the PET/CT is negative? Did that mean the cancer test yielded a false positive and I have irradiated myself for nothing, or is the cancer just too small to detect?
Does it detect dormant cancer?
Does having residual microscopic breast cancer somewhere, dormant or otherwise, mean it's an issue?
Some breast cancer survivors, particularly those who had ER+, have recurrences decades later. I read a case study of a woman in India who had a recurrence over 50 years post surgery at the mastectomy site. What if most survivors have residual cancer cells but they just never become an issue either because they never wake from dormancy or the immune system suppresses them or they are very low grade?
If the cancer test is positive and continues to be, but conventional testing and imaging doesn't find anything, does my treatment change? Probably not other than perhaps extending it for as long as the test yields positive.
What are the implications of a negative test result?
Pathologic complete response (pCR) to chemotherapy.
2018, IDC, Left, 3cm, Grade 3, ER+/PR+, HER2+ (FISH)
6/1/2018 Carboplatin (Paraplatin), Taxotere (docetaxel)
11/15/2018 Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement
Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant
Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
Arimidex (anastrozole), Zoladex (goserelin)