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All TopicsForum: Just Diagnosed → Topic: ER/PR + and HER2- (what does it all mean?)

Topic: ER/PR + and HER2- (what does it all mean?)

Forum: Just Diagnosed — Discuss next steps, options, and resources.

Posted on: May 24, 2011 12:38PM

Chrys23 wrote:

Afternoon! Newly diagnosed -- waiting to see surgeon next week. Just got back the addendum to my pathology a few minutes ago and am ER/PR+, along with HER2-

I've just started to read up but want to know from others with the same results.

Many thanks!

Chrys Kiss

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May 24, 2011 04:06PM mdg wrote:

I have the same diagnosis with those.  If you are ER/PR positive it means that your BC is dependent on estrogen to grow.  That usually means treatment with something like Tamoxifen for 5 years which is an estrogen blocker.  I will be starting Tamoxifen this week (I already did surgery and chemo).  If you are HER2 - it means you do not respond to a medicine called herceptin so that won't be a treatment for you.   HER2 + means the cancer is a bit more aggressive (from what I read - which is limited as I was HER2-).  Once you have surgery (lumpectomy or MX) the final pathology report  will help them with staging of your treatment.  Did they mention what grade you are?  (grade 1, 2 or 3). 

Maria Visit my BC Blog at breastcancerwontdefineme.blogs... Dx 12/13/2010, IDC, 1cm, Stage I, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 12/23/2010 Lumpectomy (Right) Surgery 01/27/2011 Mastectomy (Right); Prophylactic Mastectomy (Left); Reconstruction: Tissue expander placement (Both) Chemotherapy 03/03/2011 Cytoxan, Taxotere Hormonal Therapy 05/19/2011 Tamoxifen Surgery 06/22/2011 Reconstruction: Breast implants (permanent) (Both) Surgery 12/10/2011 Reconstruction: Nipple reconstruction (Both)
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May 25, 2011 02:56PM Chrys23 wrote:


Lumpectomy & SNB 6/9/11; Re-excision 7/21/11; Chemo started 8/10/11 (TC 4x - every 3 weeks); Radiation sometime in November Dx 5/17/2011, IDC, 2cm, Stage IIa, Grade 2, 1/6 nodes, ER+/PR+, HER2-