Jan 26, 2022 02:38PM
I know it was coming, but I received my official diagnosis today following a biopsy last week. Invasive ductal carcinoma, grade 3 in left breast and axillary. Still waiting for the receptor information, but they want to get me in for a PET and start chemo right away, because it is an aggressive one.
I've always pictured chemo as infusions, but I've been reading more about patients taking it orally, at home. This seems much more convenient. I don't know if that's even an option for me at this point, but had anybody tried this?
Attaching my results, in case anyone else has had a similar one and it and to provide any thoughts at all.
A. Breast, right, 12 o'clock, 3 cm from nipple, ultrasound guided core biopsy (coil-shaped marker)
- benign breast tissue with prominent stromal fibrosis
- no evidence of malignancy.
B. Breast, LEFT, 7 o'clock, 4 cm from nipple, ultrasound guided core biopsy (barrel-shaped marker)
- invasive ductal carcinoma, grade 3
- tumor is associated with a very prominent lymphoid reaction
- see Diagnostic Summary below.
C. Lymph node, LEFT axilla, ultrasound guided core biopsy (butterfly-shaped marker)
- lymph node containing metastatic poorly differentiated ductal carcinoma of breast
- metastatic tumor measures at least 6 mm in size
- no extranodal extension identified.
DIAGNOSTIC SUMMARY - BREAST BIOPSY - INVASIVE
Procedure: Ultrasound guided core biopsy
Specimen Laterality: LEFT
Tumor Site (invasive carcinoma): 7 o'clock, 4 cm from nipple
Tumor Size (greatest glass slide measurement, may underestimate size, not to be used for clinical staging): at least 7 mm (at least 0.7 cm)
Histologic Type of Invasive Carcinoma: Ductal
Histologic Grade (Nottingham Histologic Score): 3 (out of 3)
Glandular (Acinar)/Tubular Differentiation Score: 3
Nuclear Pleomorphism Score: 3
Mitotic Count Score: 2
Overall Score: 8
Ductal Carcinoma In Situ (DCIS): Not identified
Ancillary Studies: Pending on specimens B and C, with results to follow in addendum
Formalin Fixation Time Between 6 and 72 Hours (current specimen): Yes
Cold ischemic time less than 1 hour (current specimen): Yes
After review of the H&E stained slide(s) immunostains were done on block B1 to further characterize the malignant process. The tumor is positive for AE1/AE3 and GATA3. CD45 stains the very abundant inflammatory cell background and is negative in the tumor. Pan-melanoma is negative. The stains confirm the diagnosis of carcinoma, and the GATA3 positivity is compatible with a breast primary
1/26/2022, IDC, Left, 1cm, Stage IIA, Grade 3, ER+/PR-, HER2-, IHC
1/26/2022 Tecentriq (atezolizumab)
8/5/2022 Lymph node removal (Left): Underarm/Axillary; Mastectomy (Left); Prophylactic mastectomy (Right); Reconstruction (Left); Reconstruction (Right)
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