Aug 23, 2018 08:27AM JoE777 wrote:
Be sure to drink plenty of water. At least 3 quarts a day
Posted on: Jul 3, 2018 01:46PM
reading about Zometa (a bisphosphonate) and how studies are showing that taking it with your AI helps prevent bone mets.
Anyone already taking Zometa as a mets prohibitor??
Posts 31 - 57 (57 total)
Aug 23, 2018 08:27AM JoE777 wrote:
Be sure to drink plenty of water. At least 3 quarts a day
Aug 23, 2018 08:50AM JoE777 wrote:
I'm reading posts about zometo is used for prevention of bone mets. It is used as a support med to treat symptoms of cancer-hypercalcimia, bone fracture. Prolia is lightweight if you have significant mets. Took prolia when none metastatic with stage 2 on femara. If your doctor mentions it to you he must see a need
Aug 23, 2018 09:15AM PreludeSing wrote:
Thanks for the advice ladies 😊😊🙏🙏 I really appreciate it....bless you all!
Aug 24, 2018 11:17PM PreludeSing wrote:
ok...did Zometa yesterday. Felt fine, even energetic the whole day. Then, BAM!! at 10pm at night, I start shivering like crazy,, temp spikes to 38.8 and my body starts to ache like I've been rolled over by a train. Blech. Had to take neurofen. Still aching and feverish this morning. hope this goes away quickly...
Aug 24, 2018 11:42PM JoE777 wrote:PreludeSing, hang in there. My first infusion hit me the second day. Much like you. Drink plenty of water. I have an infusion every 4 weeks and each time theSE has lessened. I call it my clean up drug. it has gotten the hypercalcimia under control it and strengthened my bones. Especially in my spine and lower back. After my next infusion the onc says she can spread them out every 12 weeks . Hope you have a peaceful night. It will get better.
Aug 24, 2018 11:49PM PreludeSing wrote:
thank you so much JoE777 - just what I needed to hear...really appreciate your advice 😘. Stay well!
Aug 30, 2018 12:07AM FarAwayToo wrote:
Prelude - how are you feeling now?
My MO wanted me on Zometa as soon as I was healed from BMX, but I took some time to get clearance from my dentist - ended up extracting a tooth, and then took 2 months to heal from that at the advice of the oral surgeon. He examined me today and said that my jaw bone is fully healed and I can start on Zometa.
I just had exchange surgery and prophylactic ovary removal last week, but I feel pretty good. Wondering if I should schedule the infusion ASAP or wait a few more weeks to fully heal from this latest surgery, I will send my MO or her NP a message.
My MO wanted me on Zometa because of several trials that showed it to be beneficial in preventing bone mets, but I also have osteoporosis (in one of the hips, osteopenia in another hip and in the spine). I will be doing an infusion every 6 month.
Aug 30, 2018 06:56AM PreludeSing wrote:
Hiya Faraway...I am much better now nearly 6 days after infusion. I started to feel better about Tuesday after the Friday infusion. Wed was a little more fatigued than usual and today finally feeling a bit like my old self...
Yeah I had both my bottom teeth extracted in March this year and a general dental clean up before starting Zometa.
I would schedule the Zometa for a time when you have been feeling generally well for a weeks and are maybe 3/4 weeks out from surgery and are able to have a few days of rest after the infusion. Then have some Netflix, ibuprofen or panadol handy and drink lots of water if you can manage it to flush your system. I was literally shivering and hobbling to the bathroom and back the first night but it slowly improved.
my Onc says I tend to get the worst of the side effects so your experience may be better than mine. I also suffered horribly with AC chemo. Lost 15 kg, was horribly nauseated all the time and had mouth sores, ulcers, blackened skin, crinkly skin, you name it, I had it 🤪....after that, Taxol was like a lovely walk in a shady park 😊...
All the best Faraway 💐💐
Aug 31, 2018 04:17PM FarAwayToo wrote:
Glad to hear you are feeling better, Prelude!
Sep 2, 2018 08:12PM hopefour wrote:
I have a question...I receive zometa every 6 months and have for 3 years. How long are some of you doing it for and is there a study that states how long to do it as a preventive. You Thank you for any info.
Sep 9, 2018 05:27AM maryannecb wrote:
Hi I started Zometa 10 years ago when I ready about some early evidence for prevention of boney mets. My oncologist agreed as I alos had osteoporosis on my bone density testing. He chose to give it every 3 months...and is reluctant to stop it as he feels it may be why I am stilll disease free. I suffer bad muscle aching for 2-3 days but it is little price to pay. By the way, I am 13 years with NED.
Sep 12, 2018 02:37PM Dogwood1 wrote:
I have my first Zometa Infusion today and start Arimidex when I finish radiation in a few weeks. I am wondering if you do have the side effects are they right away? I have a 2 hour drive home and have to work tomorrow and drive back for my radiation treatment tomorrow. Just wanting a heads up on what to expect.
Sep 12, 2018 06:40PM sbelizabeth wrote:
Dogwood, I had one dose of Zometa before I was switched to Prolia. The evening of the day after the infusion was when I started feeling lousy. You should be ok for work/rads tomorrow. No guarantees, though!
Sep 12, 2018 10:47PM JoE777 wrote:
My SE doesn't show up until the next day but hangs around for about 10-14 days and is sporadic now. They decrease as time goes by. Been on a monthly infusion since March
Sep 15, 2018 02:59AM Humblepeace wrote:
I had an infusion on a Thursday afternoon around 2pm and I felt pretty well until bedtime on Friday night. I woke to get water and go to the bathroom and upon returning to be I began to shiver uncontrollably. It lasted for about an hour, I prayed the whole time. The shivering stopped and went back to sleep and awoke with some aches which I took Tylenol and it helped considerably. I have been okay since and it has been over a week ago.
Hope this helps
Sep 26, 2018 04:42PM sbelizabeth wrote:
I saw my oncologist Monday and had my every-six-months injection of denosumab (Prolia). I had one infusion of Zometa in September 2015 and then switched to Prolia.
Monday's shot makes a total of six doses of this class of drug, and my oncologist says I'm finished. All the benefit for bone health has been provided and now she wants to avoid any unpleasant drug side effects. I'm OK with it.
At the same time, she wants me to stay on Femara for at least 10 years. If/when I come off Femara, I should switch to Evista.
I'm moving from California to Colorado Springs next month, though, and leaving my beloved oncologist behind. Anyone have a recommendation for a great onc in C. Springs?
Sep 28, 2018 10:53AM SSInUK wrote:
In the UK the Marsden marshalled research and got the NHS to agree to give Zometa as an adjuvant therapy to relevant women. Every 6 months for 3 years. It has a massive long life in the body so I was told the same after 3 years you have the benefit. My stage 4 friend had the same experience of bone mets stopped in their tracks and healed by zometa. She’s 5 years from a stage 4 sx and NED on zometa and tamoxifen. Everything crossed for her. I’m the same - first infusion made me feel terrible, no SE at all on subsequent doses.
Sep 28, 2018 01:26PM FarAwayToo wrote:
Had my first Zometa infusion on the 20th. Only mild muscle aches for two days after. I did drink gallons of water and also asked for 30 min infusion.
Yesterday (27th) I had a flu shot after 6 months follow up with my oncologist. She highly recommended the shot, as she says my immune system is still recovering from chemo etc. I felt so achy last night, both muscles and joints! Low grade fever as well. Didn't sleep well at all, waking up every hour and struggling to find a comfortable position. Sort of wondering if muscle/joint aches were related to how recently I had Zometa. Anyway, by morning all aches disappeared. I'm pretty tired and dizzy from not getting enough sleep though.
I read some research that Zometa stimulates certain lymphocyte production, aiding our immune system in fighting cancer. Too scientific for me to understand all the details, but it made me feel even better about doing Zometa and feeling grateful to my MO for prescribing it right away.
Sep 28, 2018 02:00PM FarAwayToo wrote:
sbelizabeth I'm in Boulder, and going to University of Colorado Hospital in Denver for all treatments. I like my oncologist, but no "LOVE". It's not too bad of a drive to Denver, depending on which side of Springs you are, so let me know if you are interested in pursuing Denver location, and I can give you the name of my onc and more info on why I like, not Love her in the PM :).
Sep 28, 2018 02:14PM DodgersGirl wrote:
FarAwayToo- I received my flu shot last week and had the same side effects you wrote about. Never had a flu shot bother me that way. But the night of my flu shot, I couldn’t get comfortable enough to fall asleep and was sooo tired the next day.
Sep 28, 2018 03:45PM FarAwayToo wrote:
DodgesGirl - it might be specific shot. I told my PT this morning how crappy I felt (I honestly was not sure if I would be able to come to my PT session), and she said several of her patients reported this.
Sep 28, 2018 04:53PM - edited Sep 28, 2018 04:53PM by stephilosphy00
Hi everyone! I am not stage 3 and I am debating I should get Zometa or not to prevent bone mets. I have been on OS and Aromasin for more than a year, and my bone density is still normal but close to osteopenia now. Looks like the result regarding Zometa for bone mets prevention is conflicting? I am also not sure if the side effects and risk will outweigh the benefit. Any thoughts?
Sep 28, 2018 06:07PM JoE777 wrote:My oncologist has never said zometo PREVENTS bone mets. I'm on monthly infusions. My doctor gave me a handout when I began treatment. It is a supportive care drug in the category of bisphosphonates. Used as a support medication to treat symptoms of cancer such as hypercalcimia or to decrease bone fractures or pain produced by bone mets. Zometo slows down osteoclast's effect on bone.(bone pain, fractures, high calcium levels) you can go to Chemotherapy Drugs-Chemocare and look at Zometo.
Sep 29, 2018 06:11PM - edited Sep 29, 2018 06:13PM by Linda2119
sbelizabeth - I'm in Colorado Springs and I am happy with my oncologist at UCHealth. He is very compassionate and thorough - I'm very happy with his care. PM me and I can give you more information.
Oct 1, 2018 06:49PM FarAwayToo wrote:
steph, I would talk to your MO. The absolute benefit is relatively small, and wasn't demonstrated for all populations.
This BCO page breaks down stats pretty well: https://www.breastcancer.org/research-news/2011121...
Keep in mind, that percentages are relative improvement, not absolute. So, when mentioning Austrian study, the page quotes 28% improvement, however, if you look up more detailed results of the study you will see that absolute improvement was 3.4% for DFS and 2.2% for OS.
Also, most of these studies demonstrated benefit for starting zometa right away after surgery and/or chemo. My onc thinks there is enough evidence to suggest that Zometa is beneficial, but for me, personally, the choice was easy, due to confirmed osteoporosis.