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Topic: Role of Tamoxifen in Stage iii breast cancer.

Forum: Stage III Breast Cancer — You are not alone. Meet others who have Stage III breast cancer.

Posted on: Nov 7, 2018 03:28AM

munyuoke wrote:

Dear Members,

I would like to know the role of Tamoxifen in the treatment of breast cance at stage iii..

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Nov 7, 2018 11:51AM CaliKelly wrote:

Hi munyuoke, Its my understanding, basically if your tumor is what they call hormone positive, or E.R. and P.R. positive. That means they grow in response to estrogen or progesterone. Tamoxifen, for pre menopausal women blocks them from getting the effects of those hormones. For post menopausal women, Aromatase Inhibitor medications, are usually used for the same reason.

Dx 6/17/2015, IDC, Left, 6cm+, Stage IIIC, Grade 2, 8/20 nodes, ER+/PR+, HER2- (IHC) Chemotherapy 8/10/2015 TAC Surgery 1/19/2016 Lymph node removal: Left, Underarm/Axillary; Mastectomy: Left Hormonal Therapy 1/29/2016 Arimidex (anastrozole) Surgery 6/28/2016 Reconstruction (left): Silicone implant Chemotherapy 11/2/2016 Xeloda (capecitabine) Surgery 10/6/2017 Reconstruction (left): Latissimus dorsi flap Surgery Radiation Therapy Whole-breast: Breast, Lymph nodes, Chest wall
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Nov 8, 2018 07:02AM star2017 wrote:

hi there — I think calikelly explained it! I’m stage iii and I am supposed to take tamoxifen for ten years (tho I may switch to an aromatase inhibitor eventually).


Dx@37, pregnant, BRCA2+ Dx 9/2017, DCIS/IDC, Right, 6cm+, Stage IIIA, Grade 3, 4/8 nodes, ER+/PR+, HER2- Surgery 10/17/2017 Mastectomy: Right; Reconstruction (right): Tissue expander placement Chemotherapy 11/29/2017 AC + T (Taxol) Surgery 4/18/2018 Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Silicone implant Radiation Therapy 5/21/2018 Whole-breast: Breast, Lymph nodes Surgery 10/24/2018 Prophylactic ovary removal; Reconstruction (left): Silicone implant Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)

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