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Topic: lympvascular invasion after neo adjuvant chemotherap.

Forum: Stage III Breast Cancer — You are not alone. Meet others who have Stage III breast cancer.

Posted on: Apr 15, 2019 06:04PM

milmil wrote:

my mum has breast cance, first it was ilc and inoperable, so Surgaon suggest to have chemo first,my mom was then stage 3a,onco gave her  four chemo,then her surgery happene, now mum path report has come and it shows many lympvascular emboli is seen,but in the beginning core biopsy show no vascular invasio,, now really really worried cause i read many many negative things about lympvascular invasion after neo adjuvant chemotherapy,, it is said that it has very poor prognosis, Allah forbid,. 

even her cancer is now grade 3,before it was grade 2.

         

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Apr 15, 2019 06:39PM Lexica wrote:

this happened to me too. I know i'm not far out from diagnosis, but I'm here and NED so far.

Diagnosed at 34. 2 years of Ibrance via PALLAS trial (ends 4/2020) Dx 7/2017, IDC, Left, Stage IIIC, Grade 2, ER+/PR+, HER2- (IHC) Surgery 12/15/2017 Lymph node removal: Sentinel; Mastectomy: Left; Prophylactic mastectomy: Right Dx 12/27/2017, DCIS/IDC, Left, 6cm+, Stage IIIA, Grade 3, 5/11 nodes, ER+/PR+, HER2- (IHC) Radiation Therapy 1/16/2018 Whole-breast: Breast, Lymph nodes, Chest wall Hormonal Therapy Aromasin (exemestane) Chemotherapy AC + T (Taxol)
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Apr 15, 2019 06:41PM Leidy wrote:

Hi, Milmil.

I had lots of positive nodes after chemo, and lots of lymphovascular invasion on my pathology report too, and I am in the worst category for residual disease after neoadjuvant chemo. That was August 2015 and now it's April 2019, and I am absolutely fine. It is quite possible that your mother's disease and mine will recur--we just never know. However, my case shows that it's very possible to be fine several years after that grim news. I wish you and your mother the best. She's lucky to have a wonderful daughter like you!

Dx 2/6/2015, IDC, Right, 6cm+, Grade 2, 12/29 nodes, ER+/PR-, HER2- Chemotherapy 3/3/2015 AC + T (Taxol) Surgery 8/19/2015 Lymph node removal: Right, Sentinel, Underarm/Axillary; Mastectomy: Left, Right; Prophylactic mastectomy: Left Radiation Therapy 9/26/2015 Whole-breast: Breast, Lymph nodes, Chest wall
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Apr 15, 2019 08:15PM Moderators wrote:

Dear milmil,

Welcome to the BCO community. We are sorry about your mom's cancer. We are glad that you reached out here and have already received some support from our members. Please let us know if there is anything we can do to help you to navigate your way around the boards. There is a forum for Caregivers that might provide you with the support that you need. Keep us posted on how things go for your mom and you.

The Mods

To send a Private Message to the Mods: community.breastcancer.org/mem...
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Apr 16, 2019 04:20AM milmil wrote:

anyone else out there???with my mom situation?????? 

  

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Apr 16, 2019 04:21AM milmil wrote:

what your doctors said about your report??   

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Apr 17, 2019 01:05AM beauz wrote:

Hi milmil, my tumor was attached to skin(like your mum) and chest wall at the diagnosis. My MO told me the tumor was locally advanced. After chemo, the tumor felt smaller but still firmly attached to the chest wall. Anyway my post surgery pathology report was a total mess to me: no clear margins, extensive lymphovascular invasions, more than 5cm in size and was staged as IIIB,…. I went on to have more chemo after surgery. My doctors never talked about prognosis to me and I never asked either. But my MO said cancer is tricky and my surgeon said BC is in particular very sneaky. I found in this forum that many members have lived many years after diagnosis of BC with stage III and lymphovascular invasions, quite a few didn't achieve clear margins after surgery. All the best to your mum and your family.

Dx 01/Dec/2017, invasive carcinoma of mixed type. Mixed no special type(60%) and micropapillary type(40%). High grade DCIS present within and beyond invasive carcinoma. Right, 5cm, Stage IIIB, Grade 2, 3/15 nodes, ER+/PR-,Her2- Dx 5/2017, IDC, Right, 5cm, Stage IIIB, Grade 2, ER+/PR-, HER2- Chemotherapy 6/26/2017 AC + T (Taxol) Surgery 11/27/2017 Lumpectomy: Right; Lymph node removal: Right, Underarm/Axillary Chemotherapy 1/10/2018 Xeloda (capecitabine) Radiation Therapy 4/16/2018 Whole-breast: Breast Hormonal Therapy 9/17/2018 Femara (letrozole)
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Apr 17, 2019 02:41PM IAmElaine wrote:

Hi milmil. I had inoperable, locally advanced, ILC. Even after neoadjuvant chemo I still had extensive lymph invasion. I did chemo before surgery, more chemo after surgery, had radiation and have been taking Femara for over 14 years now. I hit my 15 year cancer free mark last month.

Your mom is not a statistic! Every person responds differently to treatment.

Diagnosed March 1, 2004 with stage 3C ILC, 7cm tumor with 11+ nodes
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Apr 18, 2019 03:43AM MexicoHeather wrote:

Surgery is part of the process and so is chemotherapy. My oncologist was of the opinion that shrinking a lymph node cancer first was just one approach. The final grade really can't be known until surgery, so going from grade 2 to 3 happens frequently. I'm glad you're thinking of her.

Dios es Amor. Dx 10/1/2016, IDC, Right, 3cm, Stage IIB, Grade 3, 3/17 nodes, ER+/PR+, HER2- Surgery 12/4/2016 Lymph node removal: Underarm/Axillary; Mastectomy: Right Radiation Therapy 5/9/2017 Whole-breast: Lymph nodes, Chest wall Surgery 10/9/2017 Prophylactic ovary removal Surgery 12/5/2018 Hormonal Therapy Arimidex (anastrozole) Hormonal Therapy Femara (letrozole) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Oct 13, 2019 04:59PM StellaStarr wrote:

Just saw your message....How is your Mom doing?

I know this is very scary, but perhaps my status will ease your worry. In 2008, I was diagnosed with Stage 3C breast cancer: IDC + IMPC ("metastatic lymph node cancer") + a bit of DCIS. The cancer was in my blood stream. I had 24 out of 24 nodes cancerous. Yep, 3 kinds of BC. First surgery, no clear margins so I had a second surgery. By all accounts, at the time of my initial treatment I was told I would probably only make it for another 2 years. Yet, here I am.

I am hoping your Mom is doing OK. I care.

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Dec 1, 2019 09:39PM ilovemymom4ever wrote:

Hi beauz. What chemotherspy combination was administered to you and how many sessions?

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Dec 2, 2019 12:37AM MinusTwo wrote:

LOVE - as everyone has posted, your Mom can be fine for many years. I had a 2nd round of chemo after surgery - and then radiation.

If you are not pleased with what the oncologist is telling you, you should get a second opinion.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014
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Dec 2, 2019 04:32AM ilovemymom4ever wrote:

my mom is also suffering from stage IIIB ER+/PR- Her2+ breast cancer, and is currently undergoing neoadjuvant chemotherapy, AC + T (Taxotere). She just had her 4th cycle. Doctor told her to finish all 6 cycles before the surgery. Please help me pray for clear margins and cancer no more after 6 cycles

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Dec 2, 2019 08:57AM MinusTwo wrote:

With HER2+ cancer, it's pretty standard to do chemo before surgery. And then she will likely be on Herceptin for a year. Be prepared for the docs to recommend radiation after surgery to mop up any rogue cells. Hope all goes well.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014
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Dec 2, 2019 11:11AM ilovemymom4ever wrote:

how many cycles did you undergo

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Dec 2, 2019 04:18PM MinusTwo wrote:

6 cycles of TCHP - infusions every three weeks. Surgery. Then because the tumor didn't have a complete response, 4 cycles of AC - infusions every 3 weeks. Radiation - 25 sessions. Herceptin for the rest of the year.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014
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Dec 2, 2019 05:30PM ilovemymom4ever wrote:

you're NED ever since? Congrats to you! May God bless you a very long life! What change in diet and lifestyle did you do

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Dec 2, 2019 11:59PM MinusTwo wrote:

I believe in moderation. I have always believed in moderation. That means meat, alcohol, exercise, sweets, etc. I try not to overdo anything but I don't cut out anything.

2/15/11 BMX-DCIS 2SNB clear-TEs; 9/15/11-410gummies; 3/20/13 recurrance-5.5cm,mets to lymphs, Stage IIIB IDC ER/PRneg,HER2+; TCH/Perjeta/Neulasta x6; ALND 9/24/13 1/18 nodes 4.5cm; AC chemo 10/30/13 x3; herceptin again; Rads Feb2014

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