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All TopicsForum: DCIS (Ductal Carcinoma In Situ) → Topic: IDC and DCIS (mixed) Help with understanding report!

Topic: IDC and DCIS (mixed) Help with understanding report!

Forum: DCIS (Ductal Carcinoma In Situ) — Just diagnosed, in treatment, or finished treatment for DCIS.

Posted on: Jan 18, 2010 02:32PM

LINDAGARSIDE wrote:

Hi sisters and fellow lay experts on BC.  I just got my pathology report back from surgery (lumpectomy) last week.  It now shows I have both IDC and DCIS (I thought I only had IDC).  Most of the 1.8 cm tumor is IDC but 0.2cm is DCIS.  The margins were "uninvolved" by tthe IDC.  The report says "extensive intraductal component (EIC) negative".  Also, that the "amount of DCIS as a % of total tumor volume: 3%"

There is no lymph gland involvement and the margins of everything are: "margins uninvolved by invasive carcinoma" and "distance from anterior margine: 13 mm" and "distance from posterior margin: 15mm" and then "margins uninvolved by DCIS (if present)" 

The staging is pT1c and the Ancillarty Studies:  "estrogen receptor"  immunoreactive tumor cells present (>=1%) and quantitation: 100%

(progesterone receptor and Her2/neu:  pending (results not back yet)

Does anyone out there know exactly what this means in English?

Linda Dx 12/17/2009, IDC, 1cm, Stage I, Grade 1, 0/2 nodes, ER+/PR+, HER2-
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Jan 18, 2010 02:41PM Beesie wrote:

Linda, the DCIS is not in your margins so you don't need to worry about it all.  DCIS is non-invasive cancer; IDC is invasive cancer. IDC is the more serious condition and except for the need to remove all the DCIS (which already has been done in your case), your staging and all treatments decisions will be based entirely on the amount, grade and pathology of the IDC.  So you can completely forget about the DCIS.  The fact is that in most cases IDC develops from DCIS so it's very common to find some DCIS in a pathology report on IDC.

The other things your pathology say are that:

  • Your margins are clear of both DCIS and IDC (Yeah! to that) and in fact are very large (ideal margins are 10mm or greater - yours are greater). 
  • Your nodes are clear (another very big Yeah! to that).  
  • Your cancer is highly ER+ (meaning that hormone therapy will be available to you). Someone else should confirm this one because it's not an area I'm overly familiar with.
  • The PR and HER2 status results are not back yet.

Overall, a good pathology report, except of course for the fact that you have breast cancer!

Dx 9/15/05, DCIS-MI, 6cm+ Gr3 DCIS w/IDC microinvasion, Stage IA, 0/3 nodes, ER+/PR- “No power so effectually robs the mind of all its powers of acting and reasoning as fear.” Edmund Burke
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Jan 18, 2010 03:24PM roseg wrote:

Linda - I believe you may be offered chemothearpy in addition to hormonal thearpy.

The NCCN guidelines I've read indicate that a tumor > 1 cm that is er/pr+ may benefit from chemothearpy.  You'll have to check, but you shouldn't be shocked if this comes up.

IDC "trumps" DCIS because it is invasive and potentially life-threatening. I suggest you move to the Stage I forum for more information, because with these results your diagnosis is outside the scope of this forumn. 

Rose
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Jan 18, 2010 03:42PM LINDAGARSIDE wrote:

Hi Beesie and Roseg...thank you for your respones.  I feel much more informed and relaxed...I have been connecting to the ICD site but thought I'd ask at this site about DCIS.  I'm still quite a "newbie" having only been diagosed in late December.  I think I'm still in shock about the diagnosis itself...and now I've had the surgery and have the results in my hand.  Unbelievable really.... phew.  thanks again...and good luck to both of you.  Take care and God Bless.

Linda Dx 12/17/2009, IDC, 1cm, Stage I, Grade 1, 0/2 nodes, ER+/PR+, HER2-
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Jan 18, 2010 06:24PM Lindissima wrote:

Lindagarside,

Your stats are similar to mine. A bit of advice. I was given the Oncotype Dx test which tests your tumor for two things:  how likely it isto recurr (expressed as a percentage) and how likely you are to benefit from chemotherapy. A low score means you can consider forgoing chemotherapy, if you and your onco agree. It's another bit of info to consider when you make your treatment decisions.

Be sure to request this test and do some research on it as well.  You can run a search on this site under oncotype dx and/or look on the company's website.  Most insurance now pays for this test, but not all.

I am glad you have your surgery behind you, and with good clear margins.  Best of luck and take care.  We  are here for you if you need us.

Dx 1/5/2009, IDC, 1cm, Stage IB, Grade 2, 0/2 nodes, ER+/PR+, HER2-
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Oct 9, 2014 07:38AM Mariasnow wrote:

Linda, Many good omens in your diagnosis. I hope you are doing well!

Dx 3/2/2012, IDC, Right, 3cm, Stage IIA, Grade 3, 1/12 nodes, ER-/PR-, HER2+ (FISH) Dx 3/2/2012, IDC, 1cm, Stage IIA, Grade 3, 1/12 nodes, ER-/PR-, HER2+ Surgery 3/22/2012 Mastectomy: Left, Right Chemotherapy 4/5/2012 AC + T (Taxol) Targeted Therapy 6/27/2012 Herceptin (trastuzumab) Radiation Therapy 10/7/2012 3DCRT: Breast, Lymph nodes Surgery 1/27/2013 Reconstruction (left); Reconstruction (right) Surgery 8/6/2013 Reconstruction (left) Surgery 8/6/2013 Reconstruction (right): Latissimus dorsi flap Surgery 2/24/2014 Reconstruction (left): Nipple reconstruction; Reconstruction (right): Nipple reconstruction