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Topic: Weekly Taxol group

Forum: Chemotherapy - Before, During, and After —

Regimens, side effects, and support from others going through chemo.

Posted on: Jun 7, 2012 02:23PM

Sissydi wrote:

Hey there! I didn't see a separate group for weekly Taxol treatment; thought I'd start one just so we can compare notes with each other......I always learn so much from everyone! Just finished treatment #3 this week, and so far my side effects have been loss of taste and fatigue, especially day 3-5. This has been easier on me then A/C treatment so far.
What are your experiences?

Dx 12/23/2011, IDC, 1cm, Stage IIIA, Grade 3, 5/21 nodes, ER+/PR-, HER2+
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Jan 6, 2022 06:22PM gb2115 wrote:

Gamzu, sorry about your fissure. I have had many of those over the years. Probably get back on the miralax for awhile and let it heal. Hope you feel better soon!

Dx IDC in Oct 2016, stage 2A, 1.2 cm ER/PR+ Her2-, Grade 2, 1/3 nodes, Lumpectomy + rads + tam. Age 38. 5/21 Dx IDC. 1.6 cm ER/PR+, Her2 -. Gr 2. 2/2 nodes positive. AC/T. Age 42 Dx 10/2016, IDC, Right, 1cm, Stage IIA, Grade 2, 1/3 nodes, ER+/PR+, HER2- Surgery 11/4/2016 Lumpectomy Dx 5/3/2021, IDC, Right, 1cm, Grade 2, 2/2 nodes, ER+/PR+, HER2- (IHC) Radiation Therapy Whole-breast: Breast, Lymph nodes Hormonal Therapy Aromasin (exemestane), Zoladex (goserelin) Chemotherapy AC + T (Taxol) Surgery Lymph node removal: Right Surgery Lymph node removal: Sentinel; Mastectomy: Right Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jan 8, 2022 08:35PM gamzu710 wrote:

Thanks, both of you. I restarted doing Miralax twice a day and it has been a huge help.

I thought I didn't have taste changes during Taxol but now I'm not so sure. I feel like I can taste pretty normally and that it never changed, but I'm suddenly wanting to put a lot of salt or sauces on everything and some foods that are naturally kind of bland are putting me off. I ate some roast today and had to pour chipotle mayo all over it. And the mere thought or smell of chicken is making me mildly nauseous.

I have not really had any neuropathy; maybe some barely noticeable numbness in my fingertips for a few days. I iced every time and took vitamin B6 per the NP's advice, but I've read about other people in this thread that did those things and it didn't help, so not sure why I was OK. My thumbnails are quite sore when pressed on, such as when peeling clementines, but I can't see any changes or signs that there is a problem. Maybe it will just go away.

Surgery 7/28/2021 Lumpectomy: Right; Lymph node removal: Sentinel Dx 8/3/2021, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 0/1 nodes, ER+/PR+, HER2+ Chemotherapy 10/20/2021 Taxol (paclitaxel) Targeted Therapy 10/21/2021 Herceptin (trastuzumab)
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Jan 9, 2022 07:07AM gb2115 wrote:

Back when I was on Taxol this fall, my tastes were dulled, everything except salt tasted boring. My husband made something that apparently was super salty to him and our DD, but I thought it was wonderful. Happy to say that it went back to normal. Interestingly, all three of us just weathered covid...both of them had taste changes but I didn't. I thought that was kind of funny, like finally I caught a break for once!!

Dx IDC in Oct 2016, stage 2A, 1.2 cm ER/PR+ Her2-, Grade 2, 1/3 nodes, Lumpectomy + rads + tam. Age 38. 5/21 Dx IDC. 1.6 cm ER/PR+, Her2 -. Gr 2. 2/2 nodes positive. AC/T. Age 42 Dx 10/2016, IDC, Right, 1cm, Stage IIA, Grade 2, 1/3 nodes, ER+/PR+, HER2- Surgery 11/4/2016 Lumpectomy Dx 5/3/2021, IDC, Right, 1cm, Grade 2, 2/2 nodes, ER+/PR+, HER2- (IHC) Radiation Therapy Whole-breast: Breast, Lymph nodes Hormonal Therapy Aromasin (exemestane), Zoladex (goserelin) Chemotherapy AC + T (Taxol) Surgery Lymph node removal: Right Surgery Lymph node removal: Sentinel; Mastectomy: Right Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jan 10, 2022 07:58PM movingsoccermom wrote:

Good day everyone. I had multiple progressions on my last scans so off to the Xeloda group. I very much appreciated everyones advice. Best wishes to you all!

Movingsoccermom


Dx 3/3/2015, IDC, Right, 2cm, Stage IA, Grade 2, 0/3 nodes, ER+/PR+, HER2- Surgery 4/1/2015 Lumpectomy: Right; Lymph node removal: Right, Sentinel Radiation Therapy 5/27/2015 Whole-breast: Breast, Lymph nodes Dx 5/7/2019, IDC, Right, 2cm, Stage IV, metastasized to bone/lungs/other, Grade 2, 0/3 nodes, ER+/PR+, HER2- (IHC) Targeted Therapy Ibrance (palbociclib) Hormonal Therapy Faslodex (fulvestrant)
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Jan 11, 2022 12:43AM SmoothOperator78 wrote:

i wish you the best of luck on the new regimen, movingsoccermom

Dx 7/20/2021, IDC, Left, 1cm, Stage IA, Grade 2, 0/5 nodes, ER+/PR+, HER2+ (IHC) Surgery 8/5/2021 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 8/31/2021 Taxol (paclitaxel) Targeted Therapy 8/31/2021 Herceptin (trastuzumab) Radiation Therapy 12/16/2021 Whole-breast: Breast
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Jan 11, 2022 01:30AM - edited Jan 11, 2022 01:30AM by Bonniebleu

Hi,

I have some questions if you ladies could help with? I'm scheduled to start weekly Taxol in Febafter my AC treatments. What are the major differences between the two as far as side effects go? Do you still have to take steroids with these infusions?

I really appreciate any input. Thank You so much! Stay safe!

Dx 3/31/16. Age 47, IDC right, 2cm, ER+95%, PR+95%, HER2-, oncotype 13, ki67 30%, Dx 3/31/2016, IDC, Right, 2cm, Stage IIA, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 5/11/2016 Mastectomy
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Jan 11, 2022 01:17PM 1982M wrote:

Hi Bonnieblue,

I can’t tell you the difference bc I only did weekly taxol but I did have to take steroids. Paclitaxol has a high rate of transfusion reaction as well as allergic reaction. Most people end up taking Dexamethasone IV before, and Benadryl and Pepcid as premeds.

movingsoccermom- sorry you had progression. Good luck with the new chemo.

Dx 7/13/2021, IDC, Left, <1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ Surgery 8/12/2021 Lumpectomy: Left; Lymph node removal: Sentinel Dx 9/3/2021, DCIS, Left, Stage 0, Grade 2, ER+/PR+, HER2+ Targeted Therapy 9/22/2021 Herceptin (trastuzumab) Chemotherapy 9/22/2021 Taxol (paclitaxel)
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Jan 11, 2022 10:01PM Bonniebleu wrote:

thank you 1982M : )

Dx 3/31/16. Age 47, IDC right, 2cm, ER+95%, PR+95%, HER2-, oncotype 13, ki67 30%, Dx 3/31/2016, IDC, Right, 2cm, Stage IIA, Grade 2, 0/2 nodes, ER+/PR+, HER2- Surgery 5/11/2016 Mastectomy
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Jan 12, 2022 12:51AM gamzu710 wrote:

My skin is peeling off in large flakes down both sides of my torso and winding around onto my stomach. And I've got a rough, dry, rashy thing going on under both breasts. And, weirdly, in the corners of my mouth. Any idea what this is? Do I have a fungus or something? I've been prone to angular cheilitis on the lips before but this isn't the same. I had some of this around the midway point and it faded and is now back. I wouldn't be too bothered except that my radiation consult is tomorrow and I can't imagine what that might be like starting out with my skin already peeling off. Great.

Surgery 7/28/2021 Lumpectomy: Right; Lymph node removal: Sentinel Dx 8/3/2021, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 0/1 nodes, ER+/PR+, HER2+ Chemotherapy 10/20/2021 Taxol (paclitaxel) Targeted Therapy 10/21/2021 Herceptin (trastuzumab)
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Jan 12, 2022 06:31AM gb2115 wrote:

I don't know why your skin is peeling off like that (should probably get it looked at), but when I had radiation the skin over my incision was peeling off because I had a bad glue allergy. They still radiated it and it didn't seem to affect the healing time. It was an itchy mess though....glue never again!!

Dx IDC in Oct 2016, stage 2A, 1.2 cm ER/PR+ Her2-, Grade 2, 1/3 nodes, Lumpectomy + rads + tam. Age 38. 5/21 Dx IDC. 1.6 cm ER/PR+, Her2 -. Gr 2. 2/2 nodes positive. AC/T. Age 42 Dx 10/2016, IDC, Right, 1cm, Stage IIA, Grade 2, 1/3 nodes, ER+/PR+, HER2- Surgery 11/4/2016 Lumpectomy Dx 5/3/2021, IDC, Right, 1cm, Grade 2, 2/2 nodes, ER+/PR+, HER2- (IHC) Radiation Therapy Whole-breast: Breast, Lymph nodes Hormonal Therapy Aromasin (exemestane), Zoladex (goserelin) Chemotherapy AC + T (Taxol) Surgery Lymph node removal: Right Surgery Lymph node removal: Sentinel; Mastectomy: Right Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jan 13, 2022 09:41PM gamzu710 wrote:

For those who are a bit ahead of me, how long did it take before the nose scabbiness/bleeding got better after Taxol? Or is this something that continues with Herceptin? Everything else I've been able to manage well with over-the-counter solutions but nothing touches this. I have Sinex nasal spray but would have to use it basically constantly, and while I've seen some recommendations on this board for Vaseline in the nose, most medical sites on Google suggest that this is potentially unsafe. Of all the side effects, this is the one I want gone the most as I can't get rid of it with Pepcid or lotion or whatever. I'm only one week out from the last chemo so I wasn't expecting any improvement in anything to start until maybe next week.

Surgery 7/28/2021 Lumpectomy: Right; Lymph node removal: Sentinel Dx 8/3/2021, DCIS/IDC, Right, <1cm, Stage IA, Grade 2, 0/1 nodes, ER+/PR+, HER2+ Chemotherapy 10/20/2021 Taxol (paclitaxel) Targeted Therapy 10/21/2021 Herceptin (trastuzumab)
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Jan 14, 2022 07:29AM - edited Jan 14, 2022 07:29AM by gb2115

My nose bleeds stopped shortly after stopping Taxol!

Dx IDC in Oct 2016, stage 2A, 1.2 cm ER/PR+ Her2-, Grade 2, 1/3 nodes, Lumpectomy + rads + tam. Age 38. 5/21 Dx IDC. 1.6 cm ER/PR+, Her2 -. Gr 2. 2/2 nodes positive. AC/T. Age 42 Dx 10/2016, IDC, Right, 1cm, Stage IIA, Grade 2, 1/3 nodes, ER+/PR+, HER2- Surgery 11/4/2016 Lumpectomy Dx 5/3/2021, IDC, Right, 1cm, Grade 2, 2/2 nodes, ER+/PR+, HER2- (IHC) Radiation Therapy Whole-breast: Breast, Lymph nodes Hormonal Therapy Aromasin (exemestane), Zoladex (goserelin) Chemotherapy AC + T (Taxol) Surgery Lymph node removal: Right Surgery Lymph node removal: Sentinel; Mastectomy: Right Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)
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Jan 14, 2022 08:51AM - edited Jan 14, 2022 08:53AM by 1982M

Gamzu,

I'm 5 weeks out now and thought it would stop… but it hasn't. I don't know if it's the dry weather? I'm in Canada and mid winter here. Or maybe it's the Herceptin? I'm not sure but I have crusty sore bloody noses still. I do put Vaseline inside it bc it helps. I have read that it’s not an intended use, but I don’t slather. Just a bit even helps.

On the plus side my hair is definitely growing! I definitely am getting hair. I still look bald, but now I have a hairline and some of the hairs don't look just transparent like the first ones to pop through did! Lol.

My neuropathy is still present but maybe a little less noticeable?

Hope your well and resting. Good luck with radiation! I am further behind you now bc I need surgery before I can have radiation and I don’t know if I’ll get it when it’s scheduled or if I’ll catch Covid in between…. boooo.

Take care!

Dx 7/13/2021, IDC, Left, <1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2+ Surgery 8/12/2021 Lumpectomy: Left; Lymph node removal: Sentinel Dx 9/3/2021, DCIS, Left, Stage 0, Grade 2, ER+/PR+, HER2+ Targeted Therapy 9/22/2021 Herceptin (trastuzumab) Chemotherapy 9/22/2021 Taxol (paclitaxel)
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Jan 14, 2022 07:49PM SmoothOperator78 wrote:

Fanzine, dry noses and bleeding stopped right away. If anything, the Herceptin makes my nose run.

Dx 7/20/2021, IDC, Left, 1cm, Stage IA, Grade 2, 0/5 nodes, ER+/PR+, HER2+ (IHC) Surgery 8/5/2021 Lumpectomy: Left; Lymph node removal: Sentinel Chemotherapy 8/31/2021 Taxol (paclitaxel) Targeted Therapy 8/31/2021 Herceptin (trastuzumab) Radiation Therapy 12/16/2021 Whole-breast: Breast

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