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Aug 4, 2019 09:15PM
Beesie, yes, exactly! The new TAILORx data showed similar numbers for "high clinical risk", with a 6.5% chemo benefit.
The challenge is that there was no benefit for people under 40, increasing chemo benefit the older you are between 40 and 50, and then no benefit over 50.
The experts think that this is because between 40 and 50 you are more likely to be pushed into menopause, and they think that menopause is the real benefit, not chemo.
The challenge is that this is a theory, while chemo is proven. So I'm taking the chemo route and hoping for no permanent side effects.
Skv0123- I don't know anything about Endopredict- what study guides it's usage? In my grouping (intermediate risk), TAILORx guides chemo usage.
I have ILC w pleomorphic features, my Ki67 was 40, I'm grade 2, and I have ITC in one lymph node. I think my cancer is more likely to respond to chemo given its aggressive nature, and I feel that my risk is higher than it may appear.
I also got a second opinion. My primary hospital is top 10, and I went to #2 for my second opinion. They all seem to say that OS+AI should be adequate, but also agree chemo could provide some benefit.
I am fervently hoping I made the right choice, but I think I'll sleep easier knowing I tried my best with the data I had.
Diagnosed at 42, Oncotype score 16, ITC in one node- considered node negative. Lost right implant to infection March 2020. Waiting to start reconstruction all over again.
4/8/2019, ILC, Left, 3cm, Stage IB, Grade 2, 0/3 nodes, ER+/PR+, HER2-
4/23/2019, ILC, Right, <1cm, Stage IA, Grade 2, 0/2 nodes, ER+/PR+, HER2-
5/15/2019 Lymph node removal: Sentinel; Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement
6/13/2019 Zoladex (goserelin)
8/5/2019 Cytoxan (cyclophosphamide), Taxotere (docetaxel)
11/6/2019 Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant