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Topic: Chemo For Early TNBC

Forum: Triple-Negative Breast Cancer —

Share with others who have ER-/PR-/HER2- breast cancer.

Posted on: Sep 26, 2019 10:54AM

so_chickadee wrote:

I have a question to those with early stage TNBC: did you get/recommended any chemotherapy at all? And what was your chemo regimen/protocol? Getting my cancer clinic appointment soon and hoping they won't recommend any chemo on top of bmx. 😓

BRCA1 Positive, Interval TNBC Dx 8/2019, IDC, Right, <1cm, Stage IB, Grade 2, 0/3 nodes, ER-/PR-, HER2- (FISH) Dx 9/2019, DCIS, Right, <1cm, Stage 0, Grade 2, 0/3 nodes, ER-/PR-, HER2- (FISH) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Surgery Prophylactic ovary removal Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Sep 26, 2019 11:26AM Gamb wrote:

Hi Chickadee

I have triple negative bc , mine is stage 2b and I'm doing chemo now, my regime is AC+T

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Sep 26, 2019 11:30AM MountainMia wrote:

Hi chickadee. So sorry you are dealing with this.

My understanding is that for tnbc, it is typical to recommend chemo with tumors of .5cm or greater. That said, my tumor was 1.5cm and my MO was pretty wishy-washy on the issue. I was BRCA negative. Also node negative. After discussion he and I agreed to a regimen of AC x 4, dose dense, along with my lumpectomy and radiation.

Because of your tumor size with tnbc, and the BRCA1+, you might expect a chemo recommendation. Good luck.


The rain comes and the rain goes, but the mountain remains. I am the mountain.
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Sep 26, 2019 07:15PM - edited Sep 26, 2019 07:15PM by Hope2828

Very interesting your question, I did firts surgery 2 months ago and now my chemo is capecitabine, I am currently seeking a second opinion because I understand that with tnbc intravenous chemo is always needed,

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Sep 26, 2019 10:27PM santabarbarian wrote:

My chemo was taxotere + carboplatin x 6, every 21 days.

No picnic but doable. There are a lot of TNBC people on this site and a few active threads in the TNBC forum.

TNBC is one of the few breast cancers that it seems some people CAN get rid of permanently-- so it's good to hit it hard in round one.

pCR after neoadjuvant chemo w/ integrative practices; Proton rads. Dx 7/13/2018, IDC, Left, 3cm, Stage IIB, Grade 3, ER-/PR-, HER2- (FISH) Chemotherapy 8/12/2018 Carboplatin (Paraplatin), Taxotere (docetaxel) Surgery 12/27/2018 Lumpectomy: Left Radiation Therapy 2/10/2019 Whole-breast: Breast, Lymph nodes
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Sep 26, 2019 11:16PM JudiJo wrote:

I had 6 cycles of Taxotere and Cytoxan @ 3 week intervals prior to Lumpectomy. I did not acheive pCR, so 35 rounds of radiation and 8 cycles of Xeloda after surgery.

IV Chemo, Surgery, and Radiation were totally do-able. I worked full time all the way through them. I didn't have as much energy during treatment, but aside from hair loss and some mild food aversions, no really horrible side effects.

Xeloda was more difficult, but overall, glad I did it in my situation.

I hit it hard hoping it will never come back.


Dx 8/4/2017, IDC, 2cm, Stage IIB, Grade 3, 0/1 nodes, ER-/PR-, HER2- Surgery 1/11/2018 Lumpectomy: Right Chemotherapy 6/3/2018 Xeloda (capecitabine) Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel) Radiation Therapy Whole-breast: Breast
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Sep 27, 2019 09:35AM NinjaMeow wrote:

I know it stinks but you have one chance to throw everything at TNBC the first time.Chemo is manageable.

Diagnosed at 40 Dx 10/9/2013, DCIS, Right, 1cm, Stage IA, Grade 3, 0/4 nodes, ER-/PR-, HER2- Surgery 11/20/2013 Mastectomy: Left, Right; Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Chemotherapy 12/16/2013 AC + T (Taxol)
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Sep 27, 2019 09:50AM - edited Sep 27, 2019 09:50AM by Lucyred

I had the standard ACT treatment, radiation and xeloda chemo. I would definitely consider it with TN

Dx 12/15/2017, IDC, Right, 4cm, Stage IIA, Grade 3, 0/3 nodes, ER-/PR-, HER2- (FISH) Chemotherapy 1/14/2018 AC + T (Taxol) Surgery 7/12/2018 Mastectomy: Left, Right; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 9/1/2018 Xeloda (capecitabine) Radiation Therapy 10/30/2018 Whole-breast: Breast Surgery 6/13/2019 Reconstruction (left): Tissue expander placement Surgery 9/26/2019 Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Surgery 12/9/2019 Reconstruction (left): Nipple reconstruction; Reconstruction (right): Nipple reconstruction
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Sep 27, 2019 10:20AM HappyAnyway wrote:

Hi so_chickadee. I had my final Taxol and Carboplatin today. I completed Adriamycin and Cytoxan prior to that. Chemo wasn't as bad as I anticipated. The oncologists have plenty of tricks to help with side effects. Five months of chemo was not fun, for sure. I have no regrets.

Next for me is BMX likely followed by radiation. DIEP reconstruction will be next year. I take it one treatment at a time.

Best to you.

Like... existence could be beautiful, or it could be ugly. But that's on you. Mr. Robot Dx 4/10/2019, IDC, Right, 3cm, Stage IIB, Grade 3, ER-/PR-, HER2- (IHC) Chemotherapy 4/26/2019 AC Chemotherapy 6/21/2019 Taxol (paclitaxel) Chemotherapy 7/19/2019 Carboplatin (Paraplatin) Surgery 10/30/2019 Lymph node removal: Sentinel; Mastectomy: Right; Prophylactic mastectomy: Left; Reconstruction (left): Tissue expander placement; Reconstruction (right): Tissue expander placement Chemotherapy 12/2/2019 Xeloda (capecitabine) Immunotherapy 1/17/2020 Radiation Therapy 6/8/2020 Whole-breast Dx 10/2/2020, Left, Stage IIIC, Grade 3, ER-/PR-, HER2- Surgery 11/4/2020 Mastectomy: Left; Reconstruction (left): Latissimus dorsi flap Chemotherapy 12/3/2020 Halaven (eribulin)
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Sep 30, 2019 07:21AM VL22 wrote:

Seeing that you’re BRCA + and the tumor size, I can’t see them not recommending chemo. My treatment was 4 AC and then 12 weeks of taxol. I was just so devastated when I found out I needed chemo, but then the gears shifted and I couldn’t wait to get started. I just wanted to do everything in my power to fight.

Dx 5/5/2017, IDC, Right, <1cm, Stage IA, Grade 1, 0/2 nodes, ER+/PR+, HER2- Surgery 6/15/2017 Lumpectomy: Right; Lymph node removal: Sentinel Dx 6/23/2017, IDC, Right, 1cm, Stage IB, Grade 3, 1/2 nodes, ER-/PR-, HER2- Chemotherapy 8/10/2017 AC + T (Taxol) Radiation Therapy 1/11/2018 Whole-breast: Breast Hormonal Therapy 3/11/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)

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