Oct 10, 2020 01:39PM moth wrote:

BevJen, she's tnbc acc to 2019 dx :)

Oct 11, 2020 02:32PM - edited Oct 11, 2020 02:33PM by RegiLifeme

Dear all,

I am living in Belgium and wonder if it is possible to get Sacituzumab Govitecan (Trodelvy). There were some clinical trials but they are closed now. If necessary I can go abroad to buy it (for my sister who has TNBC).

best regards

Reginald

Oct 23, 2020 02:40AM thrivingmama wrote:

Hi everyone. I just discovered this Trodelvy thread and wanted to say hi and write a quick note, then I'm off to get some sleep. I started Trodelvy in early June. I was not in good shape when I started... high liver labs, bili, etc. I developed ascites that required once a week draining from June through September. My liver was not in good shape. I'm happy to share that I am feeling so much better now. After 2 cycles of Trodelvy my scans showed that it was working. My second scan on Trodelvy showed a remarkable response, particularly in my liver, compared to before I started.

Because my liver was in such poor shape when I started Trodelvy, I started on a 50% dose. I am still on a 50% dose and seeing the great response. My ascites began dramatically improving in September and my energy, appetite, etc. is so much better. I am so thankful and grateful that Trodelvy is working for me and for so many others.

Nov 6, 2020 08:48PM Wanderingneedle wrote:

Halfway through 4th cycle. Still having difficulty adjusting to the diarrhea. Trying a dose reduction after scan showed everything is shrinking. 🎉 This is the first thing to work since I was diagnosed triple negative about a year ago so my whole family is breathing a collective sigh of relief!

I hope everyone is doing well - this thread is a bit quiet so hopefully that’s a good thing!

Libby

Nov 25, 2020 06:01PM LibrarianPatty wrote:

As you can see, there aren't that many responses. This is likely due to the fact that not that many patients are taking this drug since it is so new--approved by the FDA in April of 2020. I have been on several chemos since my diagnosis four years ago and they all have their different side effects. For this one, it has been terrible diarrhea. Have your oncologist give you a prescription for anti-diarrhea meds. It can start up even more than a week beyond the infusion. OTC stuff does not work! Other than that, as I go along with the treatment, the fatigue has gotten worse. I think that's the case for most chemos I have been on. Side effects aside, I wouldn't change it because the med is working. When i found out I was metastatic to my brain, they found 40 or 50 lesions. My scan last month, after taking Trodelvy since June, shows significant reduction in the size of the lesions and reduction in the number of lesions. They could only count 15 this time. Know that I am also taking a low dose of a niraparib (PARP Inhibitor) so that might be helping the meds to cross the blood brain barrier. I also had 10 whole brain radiation sessions back in March and April before starting chemo again. Best of luck and would love to hear from all of you since there aren't that many patients on this drug to ask questions of--at least not at my oncologists office.