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Topic: Use of certain antihistamines confers survival benefit

Forum: Clinical Trials, Research News, Podcasts, and Study Results —

Share your research articles, interpretations and experiences here. Let us know how these studies affect you and your decisions.

Posted on: Sep 5, 2019 09:08AM

claireinaz wrote:

I've been taking claritin daily since I read something similar about 4 years ago. I thought I'd see if anything was updated, and here is an abstract to an article that seems to support the benefit.

https://cancerres.aacrjournals.org/content/78/13_Supplement/5695

9/29/11 ILC, 2 c. stage II grade 1, ER/PR+ HER2-, 6/11 nodes, lumpectomy, DDAC x 4, Taxol x 12, 33 rads, Tamoxifen/arimidex/aromasin, BMX/immed recon 7/3/13 "In the midst of winter, I found in me an invincible summer.” Albert Camus
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Sep 5, 2019 09:42AM BevJen wrote:

Claireinez,

Am I reading that article correctly, or is it saying that there is an advantage to clarinex, which is slightly different from Claritin? From what I can find, clarinex is only available via prescription (just did a quick check, so might be wrong on this).

Dx 11/2003, ILC, Left, Stage IIIC, ER+/PR+, HER2- Dx 6/2006, ILC, Stage IV, metastasized to other, ER+ Dx 5/2019, ILC, Stage IV, metastasized to liver, ER+/PR+, HER2- Surgery 7/5/2019 Targeted Therapy 8/1/2019 Ibrance (palbociclib) Radiation Therapy Surgery Lymph node removal: Left, Sentinel; Mastectomy: Left, Right; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Chemotherapy TAC Hormonal Therapy Faslodex (fulvestrant) Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal; Mastectomy; Reconstruction (left): Pedicled TRAM flap; Reconstruction (right): Pedicled TRAM flap Hormonal Therapy Femara (letrozole)
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Sep 5, 2019 10:06AM claireinaz wrote:

The way I read it (which could be wrong): "Loratadine use is associated with better survival in the peri-diagnostic analysis (HR=0.78 [95% CI 0.63-0.97], P=0.022)".

Loratadine in common form: it's Claritin.


9/29/11 ILC, 2 c. stage II grade 1, ER/PR+ HER2-, 6/11 nodes, lumpectomy, DDAC x 4, Taxol x 12, 33 rads, Tamoxifen/arimidex/aromasin, BMX/immed recon 7/3/13 "In the midst of winter, I found in me an invincible summer.” Albert Camus
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Sep 5, 2019 10:07AM PinkArmor wrote:

From what I can see in research is that desloratadine and ebastine are both prescription and they are the 2 that had the best benefit. They are not the same as Claritin. The article did say that Claritin (loratidine) did have a positive effect as well, just not as great as the other 2. So if you have allergies and need it daily I guess it's good to know that it can help in this area as well.

Be stronger than the storm. Dx 3/18/2019, LCIS/DCIS, Right, 6cm+, Stage 0, Grade 3, ER+/PR+ Surgery 5/15/2019 Lumpectomy: Right; Reconstruction (left); Reconstruction (right) Hormonal Therapy 8/1/2019 Arimidex (anastrozole), Femara (letrozole) Radiation Therapy 9/3/2019 Whole-breast: Breast
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Sep 5, 2019 10:58AM Beesie wrote:

I use Aerius daily - my sinus congestion (and headaches and sore throats and jaw pain, etc.) is brutal without it.

It's not prescription (at least here in Canada), and it's desloratadine. WooHoo!

“No power so effectually robs the mind of all its powers of acting and reasoning as fear.” Edmund Burke
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Sep 5, 2019 11:28AM ksusan wrote:

This seems like big news, yet I haven't heard this. I wonder if there's been an empirical study to follow up on this descriptive report?

Mutant uprising quashed. Dx 1/2015, IDC, Right, Stage IIA, 1/1 nodes, ER+/PR+, HER2- Dx 1/2015, DCIS, Left, Stage 0, Grade 3, 0/2 nodes Hormonal Therapy Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone) Surgery Lymph node removal: Sentinel; Mastectomy: Left, Right Radiation Therapy Whole-breast Chemotherapy Cytoxan (cyclophosphamide), Taxotere (docetaxel)
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Sep 5, 2019 11:31AM wallycat wrote:

The Swedish study had originally written that Allegra (Fexofenadine) should be studied further as it was a possible. In this write up, it seems they've decided that was a no. DRAT.

Beesie, canada is so much more evolved. Hope this happens for us too!


Dx 4/07 1 month before turning 50; ILC 1.8cm, ER+/PR+, HER2 neg., Stage 1, Grade 2, 0/5 nodes. Onco score 20, Bilateral Mast., tamoxifen 3-1/2 years, arimidex-completed 4/20/2012
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Sep 5, 2019 04:19PM - edited Sep 5, 2019 04:20PM by SerenitySTAT

I've been taking Reactine (cetirizine) for years, but this year it hasn't been working as well. I'm switching to Aerius (desloratadine) now.

Thanks for the info!

"Do not overlook the little joys!" (Hesse, 1905) 🐶☕️🛀🖼🥐🌲🎭 Dx 11/2015 IDC Left IIIC 10/11 nodes ER+PR+HER2-, 12/2015 Left Mast, 2/2016 4 AC+12 Taxol, 9/2016 Rads Nodes Chest wall 15+4 boosts, 10/2016 Tamox, 4/2019 Exemestane, 12/2019 Ibrance/Xgeva

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