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Topic: Has anyone had gastritis since taking Tamoxifen?

Forum: Hormonal Therapy - Before, During, and After —

This is a safe place to share your experiences of others considering or on hormonal treatment.

Posted on: Jul 3, 2012 06:52PM

julieeee wrote:

I've been on Tamoxifen for 2 years. I've always had problems with GERD through the years, but it got much worse after I started the tamoxifen. I've tried all sorts of things--increasing the prilosec, zantac, aloe vera juice, tums, not to mention adjusting my diet every way possible. My medical oncologist says gastritis isn't a typical side effect, but I do see it mentioned on quite a few websites. I'm scared that I'll end up with stomach cancer as I'm trying to fight a breast cancer reoccurence. I'm getting an endoscopy again next week and have been trying to research tamoxifen alternatives. Has anyone else had this problem?

Dx 5/28/2010, IDC, <1cm, Stage IB, Grade 1, 0/2 nodes, ER+/PR+, HER2-
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Jul 4, 2012 06:29AM Houndmommy wrote:

INteresting.  In last few months I've had a number of acid reflux/heartburn episodes.  This is not normal for me and I've been wondering if it could be the Tamoxifen (been on it 1 1/ 2 years). 

Unimx 5/17/10 - IDC, ILC, DCIS, LCIS found. Oncotype DX 14. All tumors are ER/PR+ and HER2-. Dx 4/26/2010, IDC, 1cm, Stage I, Grade 2, 0/2 nodes, ER+/PR+, HER2-
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Jul 4, 2012 12:47PM - edited Jul 4, 2012 12:48PM by raffomimi

I hear ya! Have had heart burn for a few days and as usual any symptoms of anything and I blame the Tamoxifen!!

 I have not been eating ANY high fat foods as to cause it and I have been swallowing Gaviscon and proton pump inhibitors.

I'll solider on for a while then off to the doc for them to note this symptom(of course the mind races and thinks gastrointestional cancer as I have ILC and it has a tendency to met there!!),  but realistically it's hghly unlikely 7 months out from chemo, but then so is being dx with breast cancer @ 38!!

Hugs to everyone



3rd Aug DX ILC .2tumours T1:2.5cm T2:2.3cm E+ P+. Stage 2. Grade 2. HER2- BMX 16th Aug'11. Age38yrs at DX ,Married, Children: Girls aged 20yrs, 13yrs,12yrs & 9yrs.Tamox17th FEB '12 -July'12.Zoladex Oct'12 Dx 8/3/2011, ILC, 2cm, Stage IIA, Grade 2, 0/8 nodes, ER+/PR+, HER2- Surgery 8/15/2011 Lymph node removal: Left, Sentinel; Mastectomy: Left; Prophylactic mastectomy: Right Chemotherapy 10/28/2011 Cytoxan (cyclophosphamide), Taxotere (docetaxel) Hormonal Therapy 2/16/2012
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Oct 15, 2021 02:14PM Deamo1 wrote:

YES!! As soon as I started Tamoxifen my acid reflex got worse. Now they say gastritis. Lots of info out there but Oncologists won't admit it.

Dx 6/18/2018, ILC, Right, 4cm, Grade 1, ER+/PR+, HER2- Surgery 7/4/2018 Mastectomy: Left, Right Dx DCIS, Left, <1cm, Stage 0, 0/2 nodes, ER+/PR+, HER2-
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Oct 15, 2021 08:14PM Veeder14 wrote:

Yes, as soon as I started Tamoxifen my stomach issues got worse. I'm already on the maximum dose of Protonics, I've altered my diet and eat mostly very bland food, make sure there is food in my stomach when I take the pill, and stay upright. I've got 2 1/2 years to go and worry about burning a hole in my stomach. My MO believes me but doesn't have any answers. A couple of days I skipped taking it but not very many. I wish there was an alternative like a patch or injection besides swallowing a pill daily that irritates my stomach.

Dx 1/2/2018, ILC, Left, <1cm, Stage IB, Grade 1, 0/7 nodes, ER+/PR+, HER2- Surgery 1/25/2018 Lumpectomy: Left; Lymph node removal: Sentinel Radiation Therapy 3/7/2018 Hormonal Therapy 2/28/2019 Hormonal Therapy
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Oct 16, 2021 03:31AM Rah2464 wrote:

I actually think it is pretty common for Tamoxifen to irritate your digestion system. I really struggled with it (and at times still do if I eat something too spicy) but I cannot take any of the PPIs as I am an intermediate metabolizer of Tamoxifen and all the PPi's use the same metabolic pathway. So my Oncologist says no to them. What I have found that is helping me is a good half to full teaspoon of cinnamon in my morning oatmeal and a calcium tablet (organic version of tums) at night.

Dx 5/23/2018, IDC, Left, 1cm, Stage IA, Grade 2, 0/4 nodes, ER+/PR+, HER2- (IHC) Surgery 6/26/2018 Mastectomy: Left, Right; Reconstruction (left): Silicone implant; Reconstruction (right): Silicone implant Hormonal Therapy 7/26/2018 Tamoxifen pills (Nolvadex, Apo-Tamox, Tamofen, Tamone)

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